Synthesis and anticonvulsant activities of some triazolothiadiazole derivatives

Archiv der Pharmazie

Volumn 345, Issue 7, 2012, Pages 565-573

  Deng, Xian Qing ^a   Dong, Zheng Qi ^b   Song, Ming Xia ^a   Shu, Bing ^a   Wang, Shi Ben ^a   Quan, Zhe Shan ^a  

^a YANBIAN UNIVERSITY   (China)

^b INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

Author keywords

Anticonvulsant; Maximal electroshock; Pentylenetetrazole; Synthesis; Triazolothiadiazole

Indexed keywords

1,3,4 THIADIAZOLE DERIVATIVE; 3 MERCAPTOPROPIONIC ACID; 5,6 DIHYDRO 6 SUBSTITUTED [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE DERIVATIVE; 6 BUTYL [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6 ETHYL [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6 PHENYL [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6 PROPYL [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(2 BROMOPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(2 CHLOROPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(2 FLUOROPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(2 METHOXYPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(2 NITROPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(2,4 DICHLOROPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(2,6 DIFLUOROPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(3 CHLOROPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(3 FLUOROPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(3 METHOXYPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(3 NITROPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(4 BROMOPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(4 CHLOROPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(4 FLUOROPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(4 METHOXYPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; 6(4 NITROPHENYL) [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE; [1,2,4] TRIAZOLO [3,4 B][1,3,4] THIADIAZOLE DERIVATIVE; ANTICONVULSIVE AGENT; BICUCULLINE; CARBAMAZEPINE; PENTETRAZOLE; UNCLASSIFIED DRUG; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DEHYDROGENATION; DOSE RESPONSE; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GABAERGIC SYSTEM; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SEIZURE;

ANIMALS; ANTICONVULSANTS; CONVULSANTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROSHOCK; INJECTIONS, INTRAPERITONEAL; MICE; MICE, INBRED STRAINS; MOLECULAR STRUCTURE; SEIZURES; THIADIAZOLES; TRIAZOLES;

EID: 84863696761     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.201100326     Document Type: Article

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