Dermatitis herpetiformis: From the genetics to the development of skin lesions

Clinical and Developmental Immunology

Volumn 2012, Issue , 2012, Pages

  Bonciani, Diletta ^a   Verdelli, Alice ^a   Bonciolini, Veronica ^a   D'Errico, Antonietta ^a   Antiga, Emiliano ^a   Fabbri, Paolo ^a   Caproni, Marzia ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FC RECEPTOR; GLIADIN; GLUTEN; HLA ANTIGEN; HLA DQ2 ANTIGEN; HLA DQ8 ANTIGEN; HLA DR3 ANTIGEN; IMMUNOGLOBULIN A ANTIBODY; MYOSIN; MYOSIN IXB; PROTEIN BAX; PROTEIN BCL 2; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE ANTIBODY; UNCLASSIFIED DRUG; IMMUNOGLOBULIN A; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

APOPTOSIS; CELIAC DISEASE; CYTOKINE PRODUCTION; DERMATITIS HERPETIFORMIS; DIGESTION; ENVIRONMENTAL FACTOR; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; HAPLOTYPE; HEREDITY; HISTOPATHOLOGY; HUMAN; IMMUNE DYSREGULATION; IMMUNE RESPONSE; INFLAMMATION; KERATINOCYTE; NEUTROPENIA; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NICK END LABELING; NONHUMAN; PATHOPHYSIOLOGY; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; RACE DIFFERENCE; REVIEW; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN BIOPSY; SKIN DEFECT; ANIMAL; ENVIRONMENT; GENETICS; GENOTYPE ENVIRONMENT INTERACTION; IMMUNOLOGY; PATHOLOGY;

ANIMALS; DERMATITIS HERPETIFORMIS; ENVIRONMENT; GENE-ENVIRONMENT INTERACTION; HUMANS; IMMUNOGLOBULIN A; TRANSGLUTAMINASES;

EID: 84863694081     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2012/239691     Document Type: Review

References (82)

1. Krpti S., Dermatitis herpetiformis Clinics in Dermatology 2012 30 1 56 59
2. Bolotin D., Petronic-Rosic V., Dermatitis herpetiformis: part I. Epidemiology, pathogenesis, and clinical presentation Journal of the American Academy of Dermatology 2011 64 6 1017 1024
3. Kaukinen K., Collin P., Mki M., Latent coeliac disease or coeliac disease beyond villous atrophy? Gut 2007 56 10 1339 1340 (Pubitemid 47517820)
4. Troncone R., Jabri B., Coeliac disease and gluten sensitivity Journal of Internal Medicine 2011 269 6 582 590
5. Bolotin D., Petronic-Rosic V., Dermatitis herpetiformis: part II. Diagnosis, management, and prognosis Journal of the American Academy of Dermatology 2011 64 6 1027 1033
6. Fry L., Dermatitis herpetiformis: problems, progress and prospects European Journal of Dermatology 2002 12 6 523 531 (Pubitemid 35440786)
7. Yeh S. W., Ahmed B., Sami N., Ahmed A. R., Blistering disorders: diagnosis and treatment Dermatologic Therapy 2003 16 3 214 223 (Pubitemid 37288679)
8. Nicolas M. E. O., Krause P. K., Gibson L. E., Murray J. A., Dermatitis herpetiformis International Journal of Dermatology 2003 42 8 588 600 (Pubitemid 37025207)
9. Fabbri P., Caproni M., Dermatitis herpetiformis. Orphanet Encyclopedia, http://www.orpha.net/data/patho/GB/ uk-DermatitisHerpetiformis.pdf, 2005
10. Caproni M., Antiga E., Melani L., Fabbri P., Guidelines for the diagnosis and treatment of dermatitis herpetiformis Journal of the European Academy of Dermatology and Venereology 2009 23 6 633 638
11. Ko C. J., Colegio O. R., Moss J. E., McNiff J. M., Fibrillar IgA deposition in dermatitis herpetiformisan underreported pattern with potential clinical significance Journal of Cutaneous Pathology 2010 37 4 475 477
12. Shibahara M., Nanko H., Shimizu M., Kanda N., Kubo M., Ikeda M., Matsumoto M., Nonaka S., Shimizu H., Dermatitis herpetiformis in Japan: an update Dermatology 2002 204 1 37 42 (Pubitemid 34136812)
13. Ingen-Housz-Oro S., Dermatitis herpetiformis: a review Annales de Dermatologie et de Venereologie 2011 138 3 221 227
14. Srdy M., Tietze J., Dermatitis herpetiformis:An update of the pathogenesis Hautarzt 2009 60 8 627 632
15. Spurkland A., Ingvarsson G., Falk E. S., Knutsen I., Sollid L. M., Thorsby E., Dermatitis herpetiformis and celiac disease are both primarily associated with the HLA-DQ ( 10501, 102) or the HLA-DQ ( 103, 10302) heterodimers Tissue Antigens 1997 49 1 29 34
16. Marietta E., Black K., Camilleri M., Krause P., Rogers R. S., David C., Pittelkow M. R., Murray J. A., A new model for dermatitis herpetiformis that uses HLA-DQ8 transgenic NOD mice Journal of Clinical Investigation 2004 114 8 1090 1097 (Pubitemid 39578698)
17. Sachs J. A., Awad J., McCloskey D., Different HLA associated gene combinations contribute to susceptibility for coeliac disease and dermatitis herpetiformis Gut 1986 27 5 515 520 (Pubitemid 16079751)
18. Katz S. I., Hertz K. C., Rogentine G. N., Strober W., HLA-B8 and dermatitis herpetiformis in patients with IgA deposits in skin Archives of Dermatology 1977 113 2 155 156 (Pubitemid 8033150)
19. Katz S. I., Falchuk Z. M., Dahl M. V., Rogentine G. N., Strober W., HL-A8: a genetic link between dermatitis herpetiformis and gluten-sensitive enteropathy Journal of Clinical Investigation 1972 51 11 2977 2980
20. Karpati S., Kosnai I., Verkasalo M., HLA antigens, jejunal morphology and associated diseases in children with dermatitis herpetiformis Acta Paediatrica Scandinavica 1986 75 2 297 301 (Pubitemid 16137659)
21. Hall R. P. III, Sanders M. E., Duquesnoy R. J., Katz S. I., Shaw S., Alterations in HLA-DP and HLA-DQ antigen frequency in patients with dermatitis herpetiformis Journal of Investigative Dermatology 1989 93 4 501 505 (Pubitemid 19225496)
22. Tokunaga K., Juji T., Distribution of MHC alleles in Japanese Nippon Rinsho 1990 48 489 493
23. Hervonen K., Karell K., Holopainen P., Collin P., Partanen J., Reunala T., Concordance of dermatitis herpetiformis and celiac disease in monozygous twins Journal of Investigative Dermatology 2000 115 6 990 993 (Pubitemid 32037441)
24. Hervonen K., Hakanen M., Kaukinen K., Collin P., Reunala T., First-degree relatives are frequently affected in coeliac disease and dermatitis herpetiformis Scandinavian Journal of Gastroenterology 2002 37 1 51 55 (Pubitemid 34074733)
25. Van Belzen M. J., Meijer J. W. R., Sandkuijl L. A., Bardoel A. F. J., Mulder C. J. J., Pearson P. L., Houwen R. H. J., Wijmenga C., A major non-HLA locus in celiac disease maps to chromosome 19 Gastroenterology 2003 125 4 1032 1041 (Pubitemid 37193450)
26. Snchez E., Alizadeh B. Z., Valdigem G., Ortego-Centeno N., Jiménez-Alonso J., de Ramn E., Garca A., Lpez-Nevot M. A., Wijmenga C., Martn J., Koeleman B. P. C., MYO9B gene polymorphisms are associated with autoimmune diseases in Spanish population Human Immunology 2007 68 7 610 615 (Pubitemid 46920554)
27. Monsuur A. J., Bakker P. I. W. D., Alizadeh B. Z., Zhernakova A., Bevova M. R., Strengman E., Franke L., Slot R. V., Belzen M. J. V., Lavrijsen I. C. M., Diosdado B., Daly M. J., Mulder C. J. J., Mearin M. L., Meijer J. W. R., Meijer G. A., Oort E. V., Wapenaar M. C., Koeleman B. P. C., Wijmenga C., Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect Nature Genetics 2005 37 12 1341 1344 (Pubitemid 41722189)
28. Koskinen L. L. E., Korponay-Szabo I. R., Viiri K., Juuti-Uusitalo K., Kaukinen K., Lindfors K., Mustalahti K., Kurppa K., dny R., Pocsai Z., Széles G., Einarsdottir E., Wijmenga C., Mki M., Partanen J., Kere J., Saavalainen P., Myosin IXB gene region and gluten intolerance: linkage to coeliac disease and a putative dermatitis herpetiformis association Journal of Medical Genetics 2008 45 4 222 227 (Pubitemid 351518727)
29. Leonard J., Haffenden G., Tucker W., Gluten challenge in dermatitis herpetiformis New England Journal of Medicine 1983 308 14 816 819 (Pubitemid 13114678)
30. Lioger B., Machet M. C., Machet L., Dermatitis herpetiformis Presse Medicale 2010 39 10 1042 1048
31. Fasano A., Surprise from celiac disease Scientific American 2009 301 2 54 61
32. Matthias T., Pfeiffer S., Selmi C., Gershwin M. E., Diagnostic challenges in celiac disease and the role of the tissue transglutaminase-neo-epitope Clinical Reviews in Allergy and Immunology 2010 38 2-3 298 301
33. Schuppan D., Current concepts of celiac disease pathogenesis Gastroenterology 2000 119 1 234 242 (Pubitemid 30452598)
34. Shan L., Molberg O., Parrot I., Hausch F., Filiz F., Gray G. M., Sollid L. M., Khosla C., Structural basis for gluten intolerance in Celiac Sprue Science 2002 297 5590 2275 2279
35. Skovbjerg H., Noren O., Anthonsen D., Moller J., Sjstrm H., Gliadin is a good substrate of several transglutaminases: possible implication in the pathogenesis of coeliac disease Scandinavian Journal of Gastroenterology 2002 37 7 812 817 (Pubitemid 34836818)
36. Skovbjerg H., Koch C., Anthonsen D., Sjstrm H., Deamidation and cross-linking of gliadin peptides by transglutaminases and the relation to celiac disease Biochimica et Biophysica Acta 2004 1690 3 220 230 (Pubitemid 39423617)
37. Fleckenstein B., Molberg., Qiao S. W., Schmid D. G., Von Mlbe F. D., Elgsten K., Jung G., Sollid L. M., Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the transamidation versus deamidation reactions Journal of Biological Chemistry 2002 277 37 34109 34116
38. Fleckenstein B., Qiao S. W., Larsen M. R., Jung G., Roepstorff P., Sollid L. M., Molecular characterization of covalent complexes between tissue transglutaminase and gliadin peptides Journal of Biological Chemistry 2004 279 17 17607 17616 (Pubitemid 38560525)
39. Ciccocioppo R., Di Sabatino A., Ara C., Biagi F., Perilli M., Amicosante G., Cifone M. G., Corazza G. R., Gliadin and tissue transglutaminase complexes in normal and coeliac duodenal mucosa Clinical and Experimental Immunology 2003 134 3 516 524 (Pubitemid 37542094)
40. Nehra V., New clinical issues in celiac disease Gastroenterology Clinics of North America 1998 27 2 453 465 (Pubitemid 28325392)
41. Mantzaris G., Jewell D. P., In vivo toxicity of a synthetic dodecapeptide from A gliadin in patients with coeliac disease Scandinavian Journal of Gastroenterology 1991 26 4 392 398
42. De Ritis G., Auricchio S., Jones H. W., Lew E. J. L., Bernardin J. E., Kasarda D. D., In vitro (organ culture) studies of the toxicity of specific A-gliadin peptides in celiac disease Gastroenterology 1988 94 1 41 49 (Pubitemid 18029757)
43. Dieterich W., Esslinger B., Trapp D., Hahn E., Huff T., Seilmeier W., Wieser H., Schuppan D., Cross linking to tissue transglutaminase and collagen favours gliadin toxicity in coeliac disease Gut 2006 55 4 478 484
44. Turchin I., Barankin B., Dermatitis herpetiformis and gluten-free diet Dermatology Online Journal 2005 11 1 6
45. Garioch J. L., Lewis H. M., Sargent I., Leonard J. N., Fry L., 25 years' experience of a gluten-free diet in the treatment of dermatitis herpetiformis British Journal of Dermatology 1994 131 4 541 545 (Pubitemid 24315424)
46. Fabbri P., Immunit e Cute. Le Dermatosi a Patogenesi Immunologica Lingomed Milano, Italy. 2012, http://www.lingomed.it
47. Calabuig M., Torregosa R., Polo P., Tuset L., Tomas C., Alvarez V., Garcia-Vila A., Brines J., Vilar P., Farre C., Varea V., Serological markers and celiac disease: a new diagnostic approach? Journal of Pediatric Gastroenterology and Nutrition 1990 10 4 435 442 (Pubitemid 20146459)
48. Dieterich W., Ehnis T., Bauer M., Donner P., Volta U., Riecken E. O., Schuppan D., Identification of tissue transglutaminase as the autoantigen of celiac disease Nature Medicine 1997 3 7 797 801 (Pubitemid 27298728)
49. Caputo I., Barone M. V., Martucciello S., Lepretti M., Esposito C., Tissue transglutaminase in celiac disease: role of autoantibodies Amino Acids 2009 36 4 693 699
50. Krpti S., Dermatitis herpetiformis: close to unravelling a disease Journal of Dermatological Science 2004 34 2 83 90
51. James S. P., Prototypic disorders of gastrointestinal mucosal immune function: celiac disease and Crohn's disease Journal of Allergy and Clinical Immunology 2005 115 1 25 30 (Pubitemid 40075417)
52. Kumar V., Jarzabek-Chorzelska M., Sulej J., Rajadhyaksha M., Jablonska S., Tissue transglutaminase and endomysial antibodies-diagnostic markers of gluten-sensitive enteropathy in dermatitis herpetiformis Clinical Immunology 2001 98 3 378 382
53. Rose C., Armbruster F. P., Ruppert J., Igl B. W., Zillikens D., Shimanovich I., Autoantibodies against epidermal transglutaminase are a sensitive diagnostic marker in patients with dermatitis herpetiformis on a normal or gluten-free diet Journal of the American Academy of Dermatology 2009 61 1 39 43
54. Caproni M., Cardinali C., Renzi D., Calabr A., Fabbri P., Tissue transglutaminase antibody assessment in dermatitis herpetiformis [9] British Journal of Dermatology 2001 144 1 196 197 (Pubitemid 32154622)
55. Tursi A., Brandimarte G., Giorgetti G. M., Prevalence of antitissue transglutaminase antibodies in different degrees of intestinal damage in celiac disease Journal of Clinical Gastroenterology 2003 36 3 219 221 (Pubitemid 36232632)
56. Sardy M., Karpati S., Merkl B., Epidermal transglutaminase (Tgase 3) is the autoanitgen of dermatitis herpetiformis Journal of Experimental Medicine 2002 195 6 747 757 (Pubitemid 34259719)
57. Lorand L., Graham R. M., Transglutaminases: crosslinking enzymes with pleiotropic functions Nature Reviews Molecular Cell Biology 2003 4 2 140 156 (Pubitemid 36172696)
58. Hitomi K., Transglutaminases in skin epidermis European Journal of Dermatology 2005 15 5 313 319 (Pubitemid 41337406)
59. Donaldson M. R., Zone J. J., Schmidt L. A., Epidermal transgluaminase deposits in perilesional and uninvolved skin in patients with dermatitis herpetiformis Journal of Investigative Dermatology 2007 127 5 1268 1271 (Pubitemid 46625149)
60. Marietta E. V., Camilleri M. J., Castro L. A., Krause P. K., Pittelkow M. R., Murray J. A., Transglutaminase autoantibodies in dermatitis herpetiformis and celiac sprue Journal of Investigative Dermatology 2008 128 2 332 335
61. Heil P. M., Volc-Platzer B., Karlhofer F., Gebhart W., Huber W. D., Benesch T., Vogelsang H., Stingl G., Transglutaminases as diagnostically relevant autoantigens in patients with gluten sensitivity Journal of the German Society of Dermatology 2005 3 12 974 978 (Pubitemid 43965330)
62. Hull C. M., Liddle M., Hansen N., Meyer L. J., Schmidt L., Taylor T., Jaskowski T. D., Hill H. R., Zone J. J., Elevation of IgA anti-epidermal transglutaminase antibodies in dermatitis herpetiformis British Journal of Dermatology 2008 159 1 120 124 (Pubitemid 351874506)
63. Zone J. J., Schmidt L. A., Taylor T. B., Hull C. M., Sotiriou M. C., Jaskowski T. D., Hill H. R., Meyer L. J., Dermatitis herpetiformis sera or goat anti-transglutaminase-3 transferred to human skin-grafted mice mimics dermatitis herpetiformis immunopathology Journal of Immunology 2011 186 7 4474 4480
64. Antiga E., Caproni M., Fabbri P., Comment on dermatitis herpetiformis sera or goat anti- transglutaminase-3 transferred to human skin-grafted mice mimics dermatitis herpetiformis immunopathology Journal of Immunology 2011 187 2 595 596
65. Cardones A. R. G., Hall R. P. III, Pathophysiology of dermatitis herpetiformis: a model for cutaneous manifestations of gastrointestinal inflammation Dermatologic Clinics 2011 29 3 469 477
66. Srdy M., Krpti S., Merkl B., Paulsson M., Smyth N., Epidermal transglutaminase (TGase 3) is the autoantigen of dermatitis herpetiformis Journal of Experimental Medicine 2002 195 6 747 757 (Pubitemid 34259719)
67. Preisz K., Srdy M., Horvth A., Krpti S., Immunoglobulin, complement and epidermal transglutaminase deposition in the cutaneous vessels in dermatitis herpetiformis Journal of the European Academy of Dermatology and Venereology 2005 19 1 74 79 (Pubitemid 40268144)
68. Hall R. P. III, Dermatitis herpetiformis Journal of Investigative Dermatology 1992 99 6 873 881
69. Warren S. J. P., Cockerell C. J., Characterization of a subgroup of patients with dermatitis herpetiformis with nonclassical histologic features American Journal of Dermatopathology 2002 24 4 305 308 (Pubitemid 34810305)
70. Smith J. B., Taylor T. B., Zone J. J., The site of blister formation in dermatitis herpetiformis is within the lamina lucida Journal of the American Academy of Dermatology 1992 27 2 I 209 213
71. Cardones A. R. G., Hall R. P. III, Pathophysiology of dermatitis herpetiformis: a model for cutaneous manifestations of gastrointestinal inflammation Dermatologic Clinics 2011 29 3 469 477
72. Smith A. D., Streilein R. D., Hall R. P. III, Neutrophil CD11b, L-selectin and Fc IgA receptors in patients with dermatitis herpetiformis British Journal of Dermatology 2002 147 6 1109 1117 (Pubitemid 36963016)
73. Mukaida N., Harada A., Matsushima K., Interleukin-8 (IL-8) and monocyte chemotactic and activating factor (MCAF/MCP-1), chemokines essentially involved in inflammatory and immune reactions Cytokine and Growth Factor Reviews 1998 9 1 9 23 (Pubitemid 28280533)
74. Hall R. P. III, Takeuchi F., Benbenisty K. M., Streilein R. D., Cutaneous endothelial cell activation in normal skin of patients with dermatitis herpetiformis associated with increased serum levels of IL-8, sE-selectin, and TNF- Journal of Investigative Dermatology 2006 126 6 1331 1337 (Pubitemid 43997916)
75. Hall R. P. III, Benbenisty K. M., Mickle C., Takeuchi F., Streilein R. D., Serum IL-8 in patients with dermatitis herpetiformis is produced in response to dietary gluten Journal of Investigative Dermatology 2007 127 9 2158 2165 (Pubitemid 47258500)
76. Loft D. E., Marsh M. N., Sandle G. I., Crowe P. T., Garner V., Gordon D., Baker R., Studies of intestinal lymphoid tissue. XII. Epithelial lymphocyte and mucosal responses to rectal gluten challenge in celiac sprue Gastroenterology 1989 97 1 29 37 (Pubitemid 19190992)
77. Kristjansson G., Serra J., Lf L., Venge P., Hllgren R., Kinetics of mucosal granulocyte activation after gluten challenge in coeliac disease Scandinavian Journal of Gastroenterology 2005 40 6 662 669 (Pubitemid 40827528)
78. Strickland I., Rhodes L. E., Flanagan B. F., Friedmann P. S., TNF- and IL-8 are upregulated in the epidermis of normal human skin after UVB exposure: correlation with neutrophil accumulation and E-selectin expression Journal of Investigative Dermatology 1997 108 5 763 768 (Pubitemid 27192351)
79. Takeuchi F., Streilein R. D., Hall R. P. III, Increased E-selectin, IL-8 and IL-10 gene expression in human skin after minimal trauma Experimental Dermatology 2003 12 6 777 783 (Pubitemid 38028669)
80. Alonso-llamazares J., Gibson L. E., Rogers R. S., Clinical, pathologic, and immunopathologic features of dermatitis herpetiformis: review of the Mayo Clinic experience International Journal of Dermatology 2007 46 9 910 919 (Pubitemid 47382275)
81. Caproni M., Torchia D., Antiga E., Degl'Innocenti D., Barletta E., Baroni G., Santucci M., Fabbri P., The role of apoptosis in the pathogenesis of dermatitis herpetiformis International Journal of Immunopathology and Pharmacology 2005 18 4 691 699
82. Caproni M., Feliciani C., Fuligni A., Salvatore E., Atani L., Bianchi B., Mohammad Pour S., Proietto G., Toto P., Coscione G., Amerio P., Fabbri P., Th2-like cytokine activity in dermatitis herpetiformis British Journal of Dermatology 1998 138 2 242 247 (Pubitemid 28114125)