Dermatitis herpetiformis and celiac disease are both primarily associated with the HLA-DQ (α1*0501, β1*02) or the HLA-DQ (α1*03, β1*0302) heterodimers

Tissue Antigens

Volumn 49, Issue 1, 1997, Pages 29-34

  Spurkland, A ^a   Ingvarsson, G ^b   Falk, E S ^b   Knutsen, I ^a   Sollid, L M ^a   Thorsby, E ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

Author keywords

Celiac disease; Dermatitis herpetiformis

Indexed keywords

HLA DQ ANTIGEN;

ARTICLE; BLOOD DONOR; CELIAC DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DERMATITIS HERPETIFORMIS; HUMAN; IMMUNOGENETICS; PRIORITY JOURNAL;

EID: 0031029263     PISSN: 00012815     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-0039.1997.tb02706.x     Document Type: Article

References (28)

1. Scott BB, Losowsky MS. Proceedings: Patchiness of the mucosal abnormality in coeliac disease (CD) and dermatitis herpetiformis (DH). Gut 1975: 16: 393.
2. Reunala T, Blomqvist K, Tarpila S, Halme H, Kangas K. Gluten-free diet in dermatitis herpetiformis. I. Clinical response of skin lesions in 81 patients. Br J Dermatol 1977: 97: 473-80.
3. Katz SI, Falchuk ZM, Dahl MV, Rogentine GN, Strober W. HL-A8: a genetic link between dermatitis herpetiformis and gluten-sensitive enteropathy. J Clin Invest 1972: 51: 2977-80.
4. Solheim BG, Albrechtsen D, Thorsby E, Thune P. Strong association between an HLA-Dw3 associated B cell alloantigen and dermatitis herpetiformis. Tissue Antigens 1977: 10: 114-8.
5. Thune P, Husby G, Fausa O, Gedde-Dahl D, Baklien K, Solheim B. Immunologic and gastrointestinal abnormalities in dermatitis herpetiformis. Int J Dermatol 1979: 18: 136-41.
6. Park MS, Terasaki PI, Ahmed AR, Zone J. The 90% incidence of HLA antigen (Te24) in dermatitis herpetiformis. Tissue Antigens 1983: 22: 263-6.
7. Hall RP, Sanders ME, Duquesnoy RJ, Katz SI, Shaw S. Alterations in HLA-DP and HLA-DQ antigen frequency in patients with dermatitis herpetiformis. J Invest Dermatol 1989: 93: 501-5.
8. Yunis JJ, Ahmed AR. Immunogenetics of dermatitis herpetiformis. Clin Dermatol 1992: 9: 341-6.
9. Hall MA, Lanchbury JS, Bolsover WJ, Welsh KI, Ciclitira PJ. HLA association with dermatitis herpetiformis is accounted for by a cis or trans associated DQ heterodimer. Gut 1991: 32: 487-90.
10. Sollid LM, Markussen G, Ek J, Gjerde H, Vartdal F, Thorsby E. Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer. J Exp Med 1989: 169: 345-50.
11. Spurkland A, Sollid LM, Ronningen KS et al. Susceptibility to develop celiac disease is primarily associated with HLA-DQ alleles. Hum Immunol 1990: 29: 157-65.
12. Sollid LM, Thorsby E. The primary association of celiac disease to a given HLA-DQ alpha/beta heterodimer explains the divergent HLA-DR associations observed in various Caucasian populations. Tissue Antigens 1990: 36: 136-7.
13. Spurkland A, Sollid LM, Polanco I, Vartdal F, Thorsby E. HLA-DR and -DQ genotypes of celiac disease patients serologically typed to be non-DR3 or non-DR5/7. Hum Immunol 1992: 35: 188-92.
14. Mantovani V, Corazza GR, Bragliani M, Frisoni M, Zaniboni MG, Gasbarrini G. Asp57-negative HLA DQ beta chain and DQA1*0501 allele are essential for the onset of DQw2-positive and DQw2-negative coeliac disease, Clin Exp Immunol 1993: 91: 153-6.
15. Tighe MR, Hall MA, Ashkenazi A, Siegler E, Lanchbury JS, Ciclitira PJ. Celiac disease among Ashkenazi Jews from Israel. A study of the HLA class II alleles and their associations with disease susceptibility. Hum Immunol 1993: 38: 270-6.
16. Sollid LM, Thorsby E. HLA susceptibility genes in celiac disease: genetic mapping and role in pathogenesis [published erratum appears in Gastroenterology 1994: 106:1133]. Gastroenterology 1993: 105: 910-22.
17. Ahmed AR, Yunis JJ, Marcus-Bagley D et al. Major histocompatibility complex susceptibility genes for dermatitis herpetiformis compared with those for gluten-sensitive enteropathy. J Exp Med 1993: 178: 2067-75.
18. Kimura A, Sasazuki T. Eleventh International Histocompatibility Workshop reference protocol for the HLA DNA-typing technique. In: Tsuji K, Aizawa M, Sasazuki T, ed. HLA 1991. Proceedings of the Eleventh International Histocompatibility Workshop and Conference. Oxford: Oxford Science Publications, 1992: 397-419.
19. Verduyn W, Doxiadis II, Anholts J et al. Biotinylated DRB sequence-specific oligonucleotides. Comparison to serologic HLA-DR typing of organ donors in eurotransplant. Hum Immunol 1993: 37: 59-67.
20. Spurkland A, Knutsen I, Markussen G, Vartdal F, Egeland T, Thorsby E. HLA matching of unrelated bone marrow transplant pairs: direct sequencing of in vitro amplified HLA-DRB1 and -DQB1 genes using magnetic beads as solid support. Tissue Antigens 1993: 41: 155-64.
21. Bodmer JG, Marsh SG. Albert ED et al. Nomenclature for factors of the HLA system, 1994. Hum Immunol 1994: 41: 1-20.
22. Todd JA, Bell JI, McDevitt HO. HLA-DQ beta gene contributes to susceptibility and resistance to insulin-depen dent diabetes mellitus. Nature 1987: 329: 599-604.
23. Horn GT, Bugawan TL, Long CM, Erlich HA. Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility. Proc Natl Acad Sci U S A 1988: 85: 6012-6.
24. Tsuji K, Aizawa M, Sasazuki T, ed. HLA 1991. Proceedings of the Eleventh International Histocompatibility Workshop and Conference. Volume 1. Oxford: Oxford Science Publications, 1992: 393-518.
25. Rønningen KS, Spurkland A, Iwe T, Sollid LM, Vartdal F, Thorsby E. Novel HLA-DR2 and -DR3 haplotypes among Norwegian Caucasians. Tissue Antigens 1991: 37: 165-7.
26. Tiwaris JL, Terasaki PI. The data and the statistical methods. In: Tiwaris JL, Terasaki PI, ed. HLA and disease associations. New York: Springer Verlag, 1985: 18-27.
27. Ploski R, Ek J, Thorsby E, Sollid LM. On the HLA-DQ(alpha 1*0501, beta 1*0201)-associated susceptibility in celiac disease: a possible gene dosage effect of DQB1*0201. Tissue Antigens 1993: 41: 173-7.
28. Clerget-Darpoux F, Babron M-C, Bouguerra F et al. Synergistic effect of two HLA heterodimers in celiac disease. Hum Immunol 1996: 47: 29.