Cyclic caged morpholinos: Conformationally gated probes of embryonic gene function

Angewandte Chemie - International Edition

Volumn 51, Issue 28, 2012, Pages 6908-6911

  Yamazoe, Sayumi ^a   Shestopalov, Ilya A ^a   Provost, Elayne ^b   Leach, Steven D ^b   Chen, James K ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

antisense oligonucleotides; developmental biology; gene expression; oligonucleotides; zebrafish

Indexed keywords

ANTISENSE; ANTISENSE OLIGONUCLEOTIDES; CELL FATES; DEVELOPMENTAL BIOLOGY; GENE FUNCTION; PHOTOCONTROL; ZEBRAFISH; ZEBRAFISH EMBRYOS;

BIOLOGY; GENE EXPRESSION;

OLIGONUCLEOTIDES;

GREEN FLUORESCENT PROTEIN; MORPHOLINO OLIGONUCLEOTIDE; OLIGONUCLEOTIDE;

ANIMAL; ANIMAL EMBRYO; ARTICLE; CELL DIFFERENTIATION; CYTOLOGY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; LARVA; METABOLISM; ORGANOGENESIS; PANCREAS; PRENATAL DEVELOPMENT; ZEBRA FISH;

ANIMALS; CELL DIFFERENTIATION; EMBRYO, NONMAMMALIAN; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GREEN FLUORESCENT PROTEINS; LARVA; MORPHOLINOS; OLIGONUCLEOTIDES; ORGANOGENESIS; PANCREAS; ZEBRAFISH;

EID: 84863686436     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201201690     Document Type: Article

References (21)

1. J. Summerton, D. Weller, Antisense Nucleic Acid Drug Dev. 1997, 7, 187-195.
2. J. Heasman, M. Kofron, C. Wylie, Dev. Biol. 2000, 222, 124-134.
3. A. Nasevicius, S. C. Ekker, Nat. Genet. 2000, 26, 216-220.
4. J. S. Eisen, J. C. Smith, Development 2008, 135, 1735-1743.
5. I. A. Shestopalov, S. Sinha, J. K. Chen, Nat. Chem. Biol. 2007, 3, 650-651.
6. X. Tang, S. Maegawa, E. S. Weinberg, I. J. Dmochowski, J. Am. Chem. Soc. 2007, 129, 11000-11001.
7. A. J. Tomasini, A. D. Schuler, J. A. Zebala, A. N. Mayer, Genesis 2009, 47, 736-743.
8. A. Deiters, R. A. Garner, H. Lusic, J. M. Govan, M. Dush, N. M. Nascone-Yoder, J. A. Yoder, J. Am. Chem. Soc. 2010, 132, 15644-15650.
9. A. Tallafuss, D. Gibson, P. Morcos, Y. Li, S. Seredick, J. Eisen, P. Washbourne, Development 2012, 139, 1691-1699.
10. X. Ouyang, I. A. Shestopalov, S. Sinha, G. Zheng, C. L. Pitt, W. H. Li, A. J. Olson, J. K. Chen, J. Am. Chem. Soc. 2009, 131, 13255-13269.
11. I. A. Shestopalov, C. L. W. Pitt, J. K. Chen, Nat. Chem. Biol. 2012, 8, 270-276.
12. J. Ramstein, R. Lavery, Proc. Natl. Acad. Sci. USA 1988, 85, 7231-7235.
13. X. Tang, M. Su, L. Yu, C. Lv, J. Wang, Z. Li, Nucleic Acids Res. 2010, 38, 3848-3855.
14. M. E. Halpern, R. K. Ho, C. Walker, C. B. Kimmel, Cell 1993, 75, 99-111.
15. S. Schulte-Merker, R. K. Ho, B. G. Herrmann, C. Nusslein-Volhard, Development 1992, 116, 1021-1032.
16. S. Schulte-Merker, F. J. van Eeden, M. E. Halpern, C. B. Kimmel, C. Nusslein-Volhard, Development 1994, 120, 1009-1015.
17. Y. Kawaguchi, B. Cooper, M. Gannon, M. Ray, R. J. MacDonald, C. V. Wright, Nat. Genet. 2002, 32, 128-134.
18. E. Zecchin, A. Mavropoulos, N. Devos, A. Filippi, N. Tiso, D. Meyer, B. Peers, M. Bortolussi, F. Argenton, Dev. Biol. 2004, 268, 174-184.
19. J. W. Lin, A. V. Biankin, M. E. Horb, B. Ghosh, N. B. Prasad, N. S. Yee, M. A. Pack, S. D. Leach, Dev. Biol. 2004, 270, 474-486.
20. H. Pisharath, J. M. Rhee, M. A. Swanson, S. D. Leach, M. J. Parsons, Mech. Dev. 2007, 124, 218-229.
21. B. R. Bill, A. M. Petzold, K. J. Clark, L. A. Schimmenti, S. C. Ekker, Zebrafish 2009, 6, 69-77.