Uncoupling of sarcoplasmic reticulum Ca2+-ATPase by N-arachidonoyl dopamine. Members of the endocannabinoid family as thermogenic drugs

British Journal of Pharmacology

Volumn 166, Issue 7, 2012, Pages 2060-2069

  Mahmmoud, Y A ^a   Gaster, M ^b  

^a AARHUS UNIVERSITY   (Denmark)

^b ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

ATP depletion; Ca2+ ATPase; N arachidonoyl dopamine; oligomycin; SERCA; thermogenesis; uncoupling

Indexed keywords

ADENOSINE TRIPHOSPHATE; CAPSAICIN; ENDOCANNABINOID; N ARACHIDONOYL DOPAMINE; PROTEINASE K; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPHOSPHORYLATION; DRUG EFFICACY; DRUG MECHANISM; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MITOCHONDRION; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN SYNTHESIS; SARCOPLASMIC RETICULUM; SKELETAL MUSCLE;

ADENOSINE TRIPHOSPHATE; ADULT; ANIMALS; ARACHIDONIC ACIDS; CALCIUM; CELLS, CULTURED; DOPAMINE; FEMALE; HUMANS; MALE; MIDDLE AGED; MUSCLE FIBERS, SKELETAL; RABBITS; SARCOPLASMIC RETICULUM; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES;

EID: 84863675898     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.01899.x     Document Type: Article

References (45)

1. Alexander SPH, Mathie A, Peters JA, (2011). Guide to receptors and channels (GRAC), 5th edn. Br J Pharmacol 164 (Suppl. 1): S1-324.
2. Andersen JP, (1995). Dissection of the functional domains of the sarcoplasmic reticulum Ca(2+)-ATPase by site-directed mutagenesis. Biosci Rep 15: 243-261.
3. Arruda AP, Ketzer LA, Nigro M, Galina A, Carvalho DP, de Meis L, (2008). Cold tolerance in hypothyroid rabbits: role of skeletal muscle mitochondria and sarcoplasmic reticulum Ca-ATPase isoform 1 in heat production. Endocrinology 149: 6262-6271.
4. Balverg MGJ, Verhoeckx KCM, Witkamp RF, (2009). Development and validation of a quantitative method for the determination of 12 endocannabinoids and related compounds in human plasma using liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 877: 1583-1590.
5. 2+-ATPase: coupling effects of dimethyl sulfoxide and low temperature. J Biol Chem 277: 16868-16872.
6. Brinkmeier H, (2011). TRP channels in skeletal muscle: gene expression, function and implications for disease. Adv Exp Med Biol 704: 749-758.
7. 2+ deocclusion and release from ADP-insensitive phosphoenzyme. J Biol Chem 282: 34429-34447.
8. Eguchi Y, Shimizu S, Tsujimoto Y, (1997). Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res 57: 1835-1840.
9. Gaster M, (2007). Insulin resistance and the mitochondrial link. Lessons from cultured human myotubes. Biochim Biophys Acta 1772: 755-765.
10. Gaster M, Beck-Nielsen H, Schroder HD, (2001a). Proliferation conditions for human satellite cells. The fractional content of satellite cells. APMIS 109: 726-734.
11. Gaster M, Kristensen SR, Beck-Nielsen H, Schroder HD, (2001b). A cellular model system of differentiated human myotubes. APMIS 109: 735-744.
12. Hu SSJ, Bradshaw HB, Benton VM, Chen JSC, Huang SM, Minassi A, et al,. (2009). The biosynthesis of N-arachidonoyl dopamine, a putative endocannabinoid, via conjugation of arachidonic acid with dopamine. Prostaglandins Leukot Essent Fatty Acids 81: 291-301.
13. Huang SM, Bisogno T, Trevisani M, Al-Hayani A, De Petrocellis L, Fezza F, et al,. (2002). An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc Natl Acad Sci U S A 99: 8400-8405.
14. 2+-ATPase in the native membrane environment. Effects of pH, temperature, catalytic substrates, and thapsigargin. J Biol Chem 283: 1189-1196.
15. Kaczocha M, Glaser ST, Deutsch DG, (2008). Identification of intracellular carriers for the endocannabinoid anandamide. Proc Natl Acad Sci U S A 106: 6375-6380.
16. Klodos I, Esmann M, Post RL, (2002). Large-scale preparation of sodium-potassium ATPase from kidney outer medulla. Kidney Int 62: 2097-2100.
17. Kobayashi A, Osaka T, Namba Y, Inoue S, Lee TH, Kimura S, (1998). Capsaicin activates heat loss and heat production simultaneously and independently in rats. Am J Physiol 275: R92-R98.
18. Kramar R, Hohenegger M, Srour AN, Khanakah G, (1984). Oliomycin toxicity in intact rats. Agents Actions 15: 660-663.
19. Kühlbrandt W, (2004). Biology, structure and mechanism of P-type ATPases. Nat Rev Mol Cell Biol 5: 282-295.
20. Lenoir G, Picard M, Gauron C, Montigny C, Maréchal PL, Falson P, et al,. (2004). Functional properties of sarcoplasmic reticulum Ca-ATPase after proteolytic cleavage at Leu119-Lys120, close to the A-domain. J Biol Chem 279: 9156-9166.
21. 2+-ATPases. J Biol Chem 272: 28815-28818.
22. 2+-ATPase. J Biol Chem 283: 21418-21426.
23. Mahmmoud YA, Christensen SB, (2011). Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E2P conformation of the Na,K-ATPase. Fatty acids differentially regulate cardiac glycoside interaction with the pump. Biochim Biophys Acta 1808: 2413-2420.
24. Martin DS, Koutcher A, (2001). A concomitant ATP-depleting strategy markedly enhances anticancer agent activity. Apoptosis 6: 125-131.
25. McCarthy TV, Quane KA, Lynch PJ, (2000). Ryanodine receptor mutations in malignant hyperthermia and central core disease. Hum Mutat 15: 410-417.
26. McGrath J, Drummond G, McLachlan E, Kilkenny C, Wainwright C, (2010). Guidelines for reporting experiments involving animals: the ARRIVE guidelines. Br J Pharmacol 160: 1573-1576.
27. 2+ uptake in skeletal muscle microsomes. Inhibition by alkali ions. J Biol Chem 246: 4759-4763.
28. 2+-ATPase in thermogenesis. Biosci Rep 25: 181-190.
29. 2+-ATPase of blood platelets. Effect of the platelet activating factor. J Biol Chem 274: 28344-28350.
30. MÃ̧ller JV, Lenoir G, Marchand C, Montigny C, le Maire M, Toyoshima C, et al,. (2002). Calcium transport by sarcoplasmic reticulum Ca-ATPase. Role of the A domain and its C-terminal link with the transmembrane region. J Biol Chem 277: 38647-38659.
31. 2+ pump accounts for 50% of resting metabolic rate in mouse fast and slow twitch skeletal muscle. Am J Physiol Cell Physiol 298: C521-C529.
32. Olesen C, SÃ̧rensen TLM, Nielsen RC, MÃ̧ller JV, Nissen P, (2004). Dephosphorylation of the calcium pump coupled to counterion occlusion. Science 306: 2251-2255.
33. Olesen C, Picard M, Winther AM, Gyrup C, Morth JP, Oxvig C, et al,. (2007). The structural basis of calcium transport by the calcium pump. Nature 450: 1036-1042.
34. Park SW, Zhou Y, Lee J, Lee J, Ozcan U, (2010). Sarco(endo)plasmic reticulum Ca-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity. Proc Natl Acad Sci U S A 107: 19320-19325.
35. Reis M, Farage M, de Souza AC, de Meis L, (2001). Correlation between uncoupled ATP hydrolysis and heat production by sacroplasmic reticulum Ca-ATPase: coupling effect of fluoride. J Biol Chem 276: 42793-42800.
36. Ross HR, Gilmore AJ, Connor M, (2009). Inhibition of human recombinant T-type calcium channels by the endocannabinoid N-arachidonoyl dopamine. Br J Pharmacol 156: 740-750.
37. Scotter EL, Abood ME, Glass M, (2010). The endocannabinoid system as a target for the treatment of neurodegenerative disease. Br J Pharmacol 160: 480-498.
38. 2+ signaling mechanism in cardiac myocytes. Proc Natl Acad Sci U S A 101: 16683-16688.
39. SÃ̧rensen TL, MÃ̧ller JV, Nissen P, (2004). Phosphoryl transfer and calcium ion occlusion in the calcium pump. Science 304: 1672-1675.
40. Szallasi A, Blumberg PM, (1999). Vanilloid (capsaicin) receptors and mechanisms. Pharmacol Rev 51: 159-212.
41. Toyoshima C, Nakasako M, Nomura H, Ogawa H, (2000). Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 Ã resolution. Nature 405: 647-655.
42. Toyoshima C, Nomura H, Tsuda T, (2004). Lumenal gating mechanism revealed in calcium pump crystal structures with phosphate analogues. Nature 432: 361-368.
43. Wang J, Ueda N, (2009). Biology of endo cannabinoid synthesis system. Prostaglandins Other Lipid Mediat 89: 112-119.
44. Wold LE, Dutta K, Mason MM, Ren J, Cala SE, Schwanke ML, et al,. (2005). Impaired SERCA function contributes to cardiomyocyte dysfunction in insulin resistant rats. J Mol Cell Cardiol 39: 297-307.
45. 2+ transport by the sarcoplasmic reticulum ATPase. J Biol Chem 270: 4361-4367.