PKA and cAMP stimulate proliferation of mouse embryonic stem cells by elevating GLUT1 expression mediated by the NF-κB and CREB/CBP signaling pathways

Biochimica et Biophysica Acta - General Subjects

Volumn 1820, Issue 10, 2012, Pages 1636-1646

  Kim, Mi Ok ^a   Lee, Yu Jin ^a   Park, Jae Hong ^a   Ryu, Jung Min ^a   Yun, Seung Pil ^a   Han, Ho Jae ^b  

^a Chonnam National University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Embryonic stem cell; Glucose transporter; Nuclear factor kappa B; Proliferation; Protein kinase A

Indexed keywords

6 PHENYL CYCLIC AMP; CELL CYCLE PROTEIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DEOXYGLUCOSE; GLUCOSE; GLUCOSE TRANSPORTER 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; SMALL INTERFERING RNA; TRANSDUCER OF REGULATED CREB ACTIVITY 2 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL MEMBRANE; CELL PROLIFERATION; CELL STIMULATION; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; EMBRYONIC STEM CELL; GLUCONEOGENESIS; GLUCOSE TRANSPORT; INTRACELLULAR TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION; GLUCOSE TRANSPORTER TYPE 1; MEMBRANE PROTEINS; MICE; MODELS, BIOLOGICAL; NF-KAPPA B; PHOSPHOPROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84863656835     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2012.05.008     Document Type: Article

References (37)

1. H.J. Han, J.S. Heo, and Y.J. Lee ANG II increases 2-deoxyglucose uptake in mouse embryonic stem cells Life Sci. 77 2005 1916 1933
2. 2+/PKC, MAPKs and HIF-1α Cell. Physiol. Biochem. 19 2007 269 282
3. M. Aghayan, L.V. Rao, R.M. Smith, L. Jarett, M.J. Charron, B. Thorens, and S. Heyner Developmental expression and cellular localization of glucose transporter molecules during mouse preimplantation development Development 115 1992 305 312
4. K. Ogura, M. Sakata, Y. Okamoto, Y. Yasui, C. Tadokoro, Y. Yoshimoto, M. Yamaguchi, H. Kurachi, T. Maeda, and Y. Murata 8-bromo-cyclicAMP stimulates glucose transporter-1 expression in a human choriocarcinoma cell line J. Endocrinol. 164 2000 171 178
5. J.S. Heo, and H.J. Han ATP stimulates mouse embryonic stem cell proliferation via protein kinase C, phosphatidylinositol 3-kinase/Akt, and mitogen-activated protein kinase signaling pathways Stem Cells 24 2006 2637 2648
6. 2+/protein kinase C and epidermal growth factor receptor as well as Gli1 activation Stem Cells 25 2007 3069 3080
7. 2 and peroxisome proliferator-activated receptor δ promote mouse embryonic stem cell proliferation Stem Cells 26 2008 745 755
8. I. Ginis, Y. Luo, T. Miura, S. Thies, R. Brandenberger, N.S. Gerecht, M. Amit, A. Hoke, M.K. Carpenter, E.J. Itskovitz, and M.S. Rao Differences between human and mouse embryonic stem cells Dev. Biol. 269 2004 360 380
9. C. Heilig, F. Brosius, B. Siu, L. Concepcion, R. Mortensen, K. Heilig, M. Zhu, R. Weldon, G. Wu, and D. Conner Implications of glucose transporter protein type 1 (GLUT1)-haplodeficiency in embryonic stem cells for their survival in response to hypoxic stress Am. J. Pathol. 163 2003 1873 8185
10. S. Tonack, A. Rolletschek, A.M. Wobus, B. Fischer, and A.N. Santos Differential expression of glucose transporter isoforms during embryonic stem cell differentiation Differentiation 74 2006 499 509
11. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
12. 2+ transport in Caco-2 cell cultures Am. J. Physiol. 274 1998 G389 G396
13. C.M. Brett, C.B. Washington, R.J. Ott, M.M. Gutierrez, and K.M. Giacomini Interaction of nucleoside analogues with the sodium-nucleoside transport system in brush border membrane vesicles from human kidney Pharm. Res. 10 1993 423 426
14. E. Zhang, X. Li, S. Zhang, L. Chen, and X. Zheng Cell cycle synchronization of embryonic stem cells: effect of serum deprivation on the differentiation of embryonic bodies in vitro Biochem. Biophys. Res. Commun. 333 2005 1171 1177
15. J.C. Cheng, K. Kinjo, D.R. Judelson, J. Chang, W.S. Wu, I. Schmid, D.B. Shankar, N. Kasahara, R. Stripecke, R. Bhatia, E.M. Landaw, and K.M. Sakamoto CREB is a critical regulator of normal hematopoiesis and leukemogenesis Blood 111 2008 1182 1192
16. H. Wang, T.H. Peiris, A. Mowery, J.L. Lay, Y. Gao, and L.E. Greenbaum CCAAT/enhancer binding protein-β is a transcriptional regulator of peroxisome-proliferator-activated receptor-γ coactivator-1α in the regenerating liver Mol. Endocrinol. 22 2008 1596 1605
17. B. Njaine, R.A. Martins, M.F. Santiago, R. Linden, and M.S. Silveira Pituitary adenylyl cyclase-activating polypeptide controls the proliferation of retinal progenitor cells through downregulation of cyclin D1 Eur. J. Neurosci. 32 2010 311 321
18. M.Y. Lee, and H.J. Han Galectin-1 upregulates glucose transporter-1 expression level via protein kinase C, phosphoinositol-3 kinase, and mammalian target of rapamycin pathways in mouse embryonic stem cells Int. J. Biochem. Cell Biol. 40 2008 2421 2430
19. H.J. Han, J.S. Heo, Y.J. Lee, J.J. Min, and K.S. Park High glucose-induced inhibition of 2-deoxyglucose uptake is mediated by cAMP, protein kinase C, oxidative stress and mitogen-activated protein kinases in mouse embryonic stem cells Clin. Exp. Pharmacol. Physiol. 33 2006 211 220
20. A.M. Meneses, R.A. Medina, S. Kato, M. Pinto, M.P. Jaque, I. Lizama, M.L. García, F. Nualart, and G.I. Owen Regulation of GLUT3 and glucose uptake by the cAMP signalling pathway in the breast cancer cell line ZR-75 J. Cell. Physiol. 214 2008 110 116
21. O.Z. Zetterqvist, U. Ragnarsson, and L. Engstrom Peptides and Protein Phosphorylation 1990 CRC Press Inc. Boca Raton 171 187
22. S. Gambaryan, A. Kobsar, N. Rukoyatkina, S. Herterich, J. Geiger, A. Smolenski, S.M. Lohmann, and U. Walter Thrombin and collagen induce a feedback inhibitory signaling pathway in platelets involving dissociation of the catalytic subunit of protein kinase A from an NFκB-IκB complex J. Biol. Chem. 285 2010 18352 18363
23. H. Zhong, H. SuYang, H. Erdjument-Bromage, P. Tempst, and S. Ghosh The transcriptional activity of NF-κB is regulated by the IκB-associated PKAc subunit through a cyclic AMP-independent mechanism Cell 89 1997 413 424
24. 2+-regulated transcription factor phosphorylated by calmodulin-dependent kinases Science 252 1991 1427 1430
25. L. Xing, and P.G. Quinn Involvement of 3′,5′-cyclic adenosine monophosphate regulatory element binding protein (CREB) in both basal and hormone-mediated expression of the phosphoenolpyruvate carboxykinase (PEPCK) gene Mol. Endocrinol. 7 1993 1484 1494
26. J.C. Chrivia, R.P. Kwok, N. Lamb, M. Hagiwara, M.R. Montminy, and R.H. Goodman Phosphorylated CREB binds specifically to the nuclear protein CBP Nature 365 1993 855 859
27. P. Leahy, D.R. Crawford, G. Grossman, R.M. Gronostajski, and R.W. Hanson CREB binding protein coordinates the function of multiple transcription factors including nuclear factor I to regulate phosphoenolpyruvate carboxykinase (GTP) gene transcription J. Biol. Chem. 274 1999 8813 8822
28. S.H. Koo, L. Flechner, L. Qi, X. Zhang, R.A. Screaton, S. Jeffries, S. Hedrick, W. Xu, F. Boussouar, P. Brindle, H. Takemori, and M. Montminy The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism Nature 437 2005 1109 1111
29. K. Ravnskjaer, H. Kester, Y. Liu, X. Zhang, D. Lee, J.R. Yates 3rd, and M. Montminy Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression EMBO J. 26 2007 2880 2889
30. S. Hedrick, W. Xu, F. Boussouar, P. Brindle, H. Takemori, and M. Montminy The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism Nature 437 2005 1109 1111
31. H.A. Giebler, J.E. Loring, K. van Orden, M.A. Colgin, J.E. Garrus, and K.W. Escudero Anchoring of CREB binding protein to the human T-cell leukemia virus type 1 promoter: a molecular mechanism of Tax transactivation Mol. Cell. Biol. 17 1997 5156 5164
32. V. Iourgenko, W. Zhang, C. Mickanin, I. Daly, C. Jiang, and J.M. Hexham Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells Proc. Natl. Acad. Sci. U. S. A. 100 2003 12147 12152
33. R.W. Hanson, and L. Reshef Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression Annu. Rev. Biochem. 66 1997 581 611
34. I. Bady, C. Zitoun, L. Guignot, and G. Mithieux Activation of liver G-6-Pase in response to insulin-induced hypoglycemia or epinephrine infusion in the rat Am. J. Physiol. Endocrinol. Metab. 282 2002 E905 E910
35. L. Morris, K.E. Allen, and N.B. La Thangue Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators Nat. Cell Biol. 2 2000 232 239
36. E. Garcia-Wilson, and N.D. Perkins p21WAF1/CIP1 regulates the p300 sumoylation motif CRD1 through a C-terminal domain independently of cyclin/CDK binding Cell Cycle 4 2005 1113 1119
37. Y.M. Kim, T.R. Geiger, D.I. Egan, N. Sharma, and J.K. Nyborg The HTLV-1 tax protein cooperates with phosphorylated CREB, TORC2 and p300 to activate CRE-dependent cyclin D1 transcription Oncogene 29 2010 2142 2152