High glucose-induced inhibition of 2-deoxyglucose uptake is mediated by cAMP, protein kinase C, oxidative stress and mitogen-activated protein kinases in mouse embryonic stem cells

Clinical and Experimental Pharmacology and Physiology

Volumn 33, Issue 3, 2006, Pages 211-220

  Han, Ho Jae ^a,c   Heo, Jung Sun ^a   Lee, Yun Jung ^a   Min, Jung Jun ^b   Park, Kwang Sung ^b  

^a Department of Veterinary Medicine   (South Korea)

^b Chonnam National University Medical School   (South Korea)

^c Chonnam National University   (South Korea)

Author keywords

2 deoxyglucose uptake; cAMP; Embryonic stem cell; Mitogen activated protein kinase; Oxidative stress; Phospholipase C; Protein kinase C

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 9 (TETRAHYDRO 2 FURYL)ADENINE; ACETYLCYSTEINE; ADENYLATE CYCLASE INHIBITOR; BISINDOLYLMALEIMIDE; BISINDOLYLMALEIMIDE I; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DEOXYGLUCOSE; DEXTRAN; GLUCOSE; GLUCOSE TRANSPORTER 1; MANNITOL; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PERTUSSIS TOXIN; PHOSPHOLIPASE C INHIBITOR; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEIN P42; PROTEIN P44; REACTIVE OXYGEN METABOLITE; STAUROSPORINE; TAURINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; ATTENUATION; CONTROLLED STUDY; CYTOPLASM; DRUG INHIBITION; EMBRYONIC STEM CELL; GLUCOSE INTAKE; GLUCOSE TRANSPORT; HEXOSE TRANSPORT; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ALKALINE PHOSPHATASE; ANIMALS; ANTIMETABOLITES; BLOTTING, WESTERN; CELL MEMBRANE; CELLS, CULTURED; CYCLIC AMP; CYTOSOL; DEOXYGLUCOSE; FLUORESCENT ANTIBODY TECHNIQUE; GLUCOSE; HYDROGEN PEROXIDE; LIPID PEROXIDATION; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; OXIDATIVE STRESS; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES; RNA; STEM CELLS;

EID: 33645057199     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2006.04348.x     Document Type: Article

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