A new Cre driver mouse line, Tcf21/Pod1-Cre, targets metanephric mesenchyme

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Maezawa, Yoshiro ^a   Binnie, Matthew ^b   Li, Chengjin ^a   Thorner, Paul ^c   Hui, Chi Chung ^c   Alman, Benjamin ^c,d   Taketo, Makoto Mark ^e   Quaggin, Susan E ^a,b,f  

^a MOUNT SINAI HOSPITAL   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e KYOTO UNIVERSITY   (Japan)

^f UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CRE RECOMBINASE; PROTEIN PATCHED 1; SONIC HEDGEHOG PROTEIN;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BETA CATENIN GENE; CONTROLLED STUDY; EMBRYO; GAIN OF FUNCTION MUTATION; GENE; GENE DELETION; GENE TARGETING; HYDRONEPHROSIS; INTRACELLULAR TRANSPORT; KIDNEY CYST; KIDNEY INTERSTITIUM; LEYDIG CELL; MOUSE; MOUSE STRAIN; NONHUMAN; PATCHED 1 GENE; PHENOTYPIC VARIATION; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; STROMA CELL; TCF21 GENE;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BETA CATENIN; BREEDING; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE ORDER; GENE TARGETING; GENETIC VECTORS; INTEGRASES; KIDNEY; MALE; MESODERM; MICE; MICE, TRANSGENIC; POLYCYSTIC KIDNEY DISEASES; PROMOTER REGIONS, GENETIC; RECEPTORS, CELL SURFACE;

ERINACEIDAE; MUS;

EID: 84863653405     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040547     Document Type: Article

References (36)

1. Belteki G, Haigh J, Kabacs N, Haigh K, Sison K, et al. (2005) Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction. Nucleic Acids Res 33: e51.
2. Maezawa Y, Kreidberg JA, Quaggin SE, (2012) CHAPTER 1- Embryology of the Kidney. Brenner and Rector's the Kidney. Philadelphia, PA: W.B. Saunders Company.
3. Dressler GR, (2009) Advances in early kidney specification, development and patterning. Development 136: 3863-3874.
4. Kobayashi A, Valerius MT, Mugford JW, Carroll TJ, Self M, et al. (2008) Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell 3: 169-181.
5. Srinivas S, Goldberg MR, Watanabe T, D'Agati V, al-Awqati Q, et al. (1999) Expression of green fluorescent protein in the ureteric bud of transgenic mice: a new tool for the analysis of ureteric bud morphogenesis. Dev Genet 24: 241-251.
6. Engleka KA, Gitler AD, Zhang M, Zhou DD, High FA, et al. (2005) Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives. Dev Biol 280: 396-406.
7. Li J, Chen F, Epstein JA, (2000) Neural crest expression of Cre recombinase directed by the proximal Pax3 promoter in transgenic mice. Genesis 26: 162-164.
8. Humphreys BD, Lin SL, Kobayashi A, Hudson TE, Nowlin BT, et al. (2010) Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol 176: 85-97.
9. Shan J, Jokela T, Skovorodkin I, Vainio S, (2010) Mapping of the fate of cell lineages generated from cells that express the Wnt4 gene by time-lapse during kidney development. Differentiation 79: 57-64.
10. Quaggin SE, Schwartz L, Post M, Rossant J, (1999) The basic-helix-loop-helix protein Pod-1 is critically important for kidney and lung organogenesis. Development 126: 5771-5783.
11. Cui S, Schwartz L, Quaggin SE, (2003) Pod1 is required in stromal cells for glomerulogenesis. Dev Dyn 226: 512-522.
12. Cui S, Li C, Ema M, Rossant J, Weinstein J, et al. (2005) Rapid Isolation of Glomeruli Coupled with Gene Expression Profiling Identifies Downstream Targets in Pod1 Knockout Mice. JASN 16: 3247-3255.
13. Eremina V, Wong MA, Cui S, Schwartz L, Quaggin SE, (2002) Glomerular-specific gene excision in vivo. J Am Soc Nephrol 13: 788-793.
14. Nagy A, Rossant J, Nagy R, Abramow-Newerly W, Roder JC, (1993) Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci U S A 90: 8424-8428.
15. Novak A, Guo C, Yang W, Nagy A, Lobe CG, (2000) Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision. Genesis 28: 147-155.
16. Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, et al. (2001) Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development 128: 1253-1264.
17. Harada N, Tamai Y, Ishikawa T, Sauer B, Takaku K, et al. (1999) Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. Embo J 18: 5931-5942.
18. Ellis T, Smyth I, Riley E, Graham S, Elliot K, et al. (2003) Patched 1 conditional null allele in mice. Genesis 36: 158-161.
19. Stark K, Vainio S, Vassileva G, McMahon AP, (1994) Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 372: 679-683.
20. Park JS, Valerius MT, McMahon AP, (2007) Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development. Development 134: 2533-2539.
21. Yu J, Carroll TJ, Rajagopal J, Kobayashi A, Ren Q, et al. (2009) A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney. Development 136: 161-171.
22. Miyazaki Y, Oshima K, Fogo A, Hogan BL, Ichikawa I, (2000) Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter. J Clin Invest 105: 863-873.
23. Wang GJ, Brenner-Anantharam A, Vaughan ED, Herzlinger D, (2009) Antagonism of BMP4 signaling disrupts smooth muscle investment of the ureter and ureteropelvic junction. J Urol 181: 401-407.
24. Grigoryan T, Wend P, Klaus A, Birchmeier W, (2008) Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. Genes Dev 22: 2308-2341.
25. Pietila I, Ellwanger K, Railo A, Jokela T, Barrantes Idel B,et al. Secreted Wnt antagonist Dickkopf-1 controls kidney papilla development coordinated by Wnt-7b signalling. Dev Biol 353: 50-60.
26. Tasouri E, Tucker KL, (2011) Primary cilia and organogenesis: is Hedgehog the only sculptor? Cell Tissue Res 345: 21-40.
27. Hahn H, Wicking C, Zaphiropoulous PG, Gailani MR, Shanley S, et al. (1996) Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 85: 841-851.
28. Johnson RL, Rothman AL, Xie J, Goodrich LV, Bare JW, et al. (1996) Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 272: 1668-1671.
29. Taylor MD, Liu L, Raffel C, Hui CC, Mainprize TG, et al. (2002) Mutations in SUFU predispose to medulloblastoma. Nat Genet 31: 306-310.
30. Hu MC, Mo R, Bhella S, Wilson CW, Chuang PT, et al. (2006) GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis. Development 133: 569-578.
31. Cain JE, Islam E, Haxho F, Chen L, Bridgewater D, et al. (2009) GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells. PLoS One 4: e7313.
32. Yu J, Carroll TJ, McMahon AP, (2002) Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney. Development 129: 5301-5312.
33. Lu J, Richardson JA, Olson EN, (1998) Capsulin: a novel bHLH transcription factor expressed in epicardial progenitors and mesenchyme of visceral organs. Mech Dev 73: 23-32.
34. Robb L, Mifsud L, Hartley L, Biben C, Copeland NG, et al. (1998) epicardin: A novel basic helix-loop-helix transcription factor gene expressed in epicardium, branchial arch myoblasts, and mesenchyme of developing lung, gut, kidney, and gonads. Dev Dyn 213: 105-113.
35. Robyn J. Quinlan JLT, Philip L Beales, (2008) Modeling Ciliopathies: Primary Cilia in Development and Disease. Current Topics in Developmental Biology, Volume 84: 250-310.
36. Attanasio M, Uhlenhaut NH, Sousa VH, O'Toole JF, Otto E, et al. (2007) Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis. Nat Genet 39: 1018-1024.