-
1
-
-
70350361222
-
Comparative survival with diverse chemotherapy regimens for cancer of unknown primary site: Multiple-treatments meta-analysis
-
Golfinopoulos V, Pentheroudakis G, Salanti G, Nearchou AD, Io-annidis JP, Pavlidis N (2009) Comparative survival with diverse chemotherapy regimens for cancer of unknown primary site: multiple-treatments meta-analysis. Cancer Treat Rev 35:570-573
-
(2009)
Cancer Treat Rev
, vol.35
, pp. 570-573
-
-
Golfinopoulos, V.1
Pentheroudakis, G.2
Salanti, G.3
Nearchou, A.D.4
Io-Annidis, J.P.5
Pavlidis, N.6
-
2
-
-
67650660754
-
The Notch signaling pathway: Transcriptional regulation at Notch target genes
-
Borggrefe T, Oswald F (2009) The Notch signaling pathway: transcriptional regulation at Notch target genes. Cell Mol Life Sci 66:1631-1646
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 1631-1646
-
-
Borggrefe, T.1
Oswald, F.2
-
3
-
-
33644752839
-
Notch signaling
-
Miele L (2006) Notch signaling. Clin Cancer Res 12:1074-1079
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1074-1079
-
-
Miele, L.1
-
5
-
-
77953523118
-
The role of Notch signaling pathway in epithelial-mesenchymal transition (EMT) during development and tumor aggressiveness
-
Wang Z, Li Y, Kong D, Sarkar FH (2010) The role of Notch signaling pathway in epithelial-mesenchymal transition (EMT) during development and tumor aggressiveness. Curr Drug Targets 11:745-751
-
(2010)
Curr Drug Targets
, vol.11
, pp. 745-751
-
-
Wang, Z.1
Li, Y.2
Kong, D.3
Sarkar, F.H.4
-
7
-
-
34547209343
-
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
-
McCubrey JA, Steelman LS, Chappell WH, Abrams SL, Wong EW, Chang F, Lehmann B, Terrian DM, Milella M, Tafuri A, Stivala F, Libra M, Basecke J, Evangelisti C, Martelli AM, Franklin RA (2007) Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta 1773:1263-1284
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1263-1284
-
-
McCubrey, J.A.1
Steelman, L.S.2
Chappell, W.H.3
Abrams, S.L.4
Wong, E.W.5
Chang, F.6
Lehmann, B.7
Terrian, D.M.8
Milella, M.9
Tafuri, A.10
Stivala, F.11
Libra, M.12
Basecke, J.13
Evangelisti, C.14
Martelli, A.M.15
Franklin, R.A.16
-
8
-
-
0037342272
-
Raf-1 and Bcl-2 induce distinct and common pathways that contribute to breast cancer drug resistance
-
Davis JM, Navolanic PM, Weinstein-Oppenheimer CR, Steelman LS, Hu W, Konopleva M, Blagosklonny MV, McCubrey JA (2003) Raf-1 and Bcl-2 induce distinct and common pathways that contribute to breast cancer drug resistance. Clin Cancer Res 9:1161-1170
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1161-1170
-
-
Davis, J.M.1
Navolanic, P.M.2
Weinstein-Oppenheimer, C.R.3
Steelman, L.S.4
Hu, W.5
Konopleva, M.6
Blagosklonny, M.V.7
McCubrey, J.A.8
-
9
-
-
0345601083
-
Met, metastasis, motility and more
-
Birchmeier C, Birchmeier W, Gherardi E, Vande Woude GF (2003) Met, metastasis, motility and more. Nat Rev Mol Cell Biol 4:915-925
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 915-925
-
-
Birchmeier, C.1
Birchmeier, W.2
Gherardi, E.3
Vande Woude, G.F.4
-
10
-
-
0037905503
-
Diagnostic and therapeutic management of cancer of an unknown primary
-
Pavlidis N, Briasoulis E, Hainsworth J, Greco FA (2003) Diagnostic and therapeutic management of cancer of an unknown primary. Eur J Cancer 39:1990-2005
-
(2003)
Eur J Cancer
, vol.39
, pp. 1990-2005
-
-
Pavlidis, N.1
Briasoulis, E.2
Hainsworth, J.3
Greco, F.A.4
-
11
-
-
33644830699
-
Reporting recommendations for tumor marker prognostic studies
-
McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM (2005) Reporting recommendations for tumor marker prognostic studies. J Clin Oncol 23:9067-9072
-
(2005)
J Clin Oncol
, vol.23
, pp. 9067-9072
-
-
McShane, L.M.1
Altman, D.G.2
Sauerbrei, W.3
Taube, S.E.4
Gion, M.5
Clark, G.M.6
-
12
-
-
0033966154
-
Overexpres-sion of Her-2 in patients with poorly differentiated carcinoma or poorly differentiated adenocarcinoma of unknown primary site
-
Hainsworth JD, Lennington WJ, Greco FA (2000) Overexpres-sion of Her-2 in patients with poorly differentiated carcinoma or poorly differentiated adenocarcinoma of unknown primary site. J Clin Oncol 18:632-635
-
(2000)
J Clin Oncol
, vol.18
, pp. 632-635
-
-
Hainsworth, J.D.1
Lennington, W.J.2
Greco, F.A.3
-
13
-
-
0029549980
-
Overexpression of C-myc, Ras and C-erbB-2 oncoproteins in carcinoma of unknown primary origin
-
Pavlidis N, Briassoulis E, Bai M, Fountzilas G, Agnantis N (1995) Overexpression of C-myc, Ras and C-erbB-2 oncoproteins in carcinoma of unknown primary origin. Anticancer Res 15: 2563-2567
-
(1995)
Anticancer Res
, vol.15
, pp. 2563-2567
-
-
Pavlidis, N.1
Briassoulis, E.2
Bai, M.3
Fountzilas, G.4
Agnantis, N.5
-
14
-
-
34247611517
-
Global profiling of EGFR gene mutation, amplification, regulation and tissue protein expression in unknown primary carcinomas: To target or not to target?
-
Dova L, Pentheroudakis G, Georgiou I, Malamou-Mitsi V, Var-tholomatos G, Fountzilas G, Kolaitis N, Kitsiou E, Pavlidis N (2007) Global profiling of EGFR gene mutation, amplification, regulation and tissue protein expression in unknown primary carcinomas: to target or not to target? Clin Exp Metastasis 24:79-86
-
(2007)
Clin Exp Metastasis
, vol.24
, pp. 79-86
-
-
Dova, L.1
Pentheroudakis, G.2
Georgiou, I.3
Malamou-Mitsi, V.4
Var-Tholomatos, G.5
Fountzilas, G.6
Kolaitis, N.7
Kitsiou, E.8
Pavlidis, N.9
-
15
-
-
41849130666
-
Targeting c-KIT, PDGFR in cancer of unknown primary: A screening study for molecular markers of benefit
-
Dova L, Pentheroudakis G, Golfinopoulos V, Malamou-Mitsi V, Georgiou I, Vartholomatos G, Ntemou A, Fountzilas G, Pavlidis N (2008) Targeting c-KIT, PDGFR in cancer of unknown primary: a screening study for molecular markers of benefit. J Cancer Res Clin Oncol 134:697-704
-
(2008)
J Cancer Res Clin Oncol
, vol.134
, pp. 697-704
-
-
Dova, L.1
Pentheroudakis, G.2
Golfinopoulos, V.3
Malamou-Mitsi, V.4
Georgiou, I.5
Vartholomatos, G.6
Ntemou, A.7
Fountzilas, G.8
Pavlidis, N.9
-
16
-
-
0031927260
-
Bcl2 and p53 protein expression in metastatic carcinoma of unknown primary origin: Biological and clinical implications. A Hellenic Cooperative Oncology Group study
-
Briasoulis E, Tsokos M, Fountzilas G, Bafaloukos D, Kosmidis P, Samantas E, Skarlos D, Nicolaides C, Pavlidis N (1998) Bcl2 and p53 protein expression in metastatic carcinoma of unknown primary origin: biological and clinical implications. A Hellenic Cooperative Oncology Group study. Anticancer Res 18:1907-1914
-
(1998)
Anticancer Res
, vol.18
, pp. 1907-1914
-
-
Briasoulis, E.1
Tsokos, M.2
Fountzilas, G.3
Bafaloukos, D.4
Kosmidis, P.5
Samantas, E.6
Skarlos, D.7
Nicolaides, C.8
Pavlidis, N.9
-
17
-
-
24044517760
-
Angiogenesis in cancer of unknown primary: Clinicopathological study of CD34, VEGF and TSP-1
-
Karavasilis V, Malamou-Mitsi V, Briasoulis E, Tsanou E, Kitsou E, Kalofonos H, Fountzilas G, Fotsis T, Pavlidis N (2005) Angiogenesis in cancer of unknown primary: clinicopathological study of CD34, VEGF and TSP-1. BMC Cancer 5:25
-
(2005)
BMC Cancer
, vol.5
, pp. 25
-
-
Karavasilis, V.1
Malamou-Mitsi, V.2
Briasoulis, E.3
Tsanou, E.4
Kitsou, E.5
Kalofonos, H.6
Fountzilas, G.7
Fotsis, T.8
Pavlidis, N.9
-
18
-
-
79958204138
-
Treatment of carcinoma of unknown primary site (CUP) directed by molecular profiling diagnosis: A prospective, phase II trial
-
Hainsworth JD, Spigel DR, Rubin MS, Boccia RV, Fox EP, Firdaus I, Erlander MG, Schnabel C, Greco FA (2010) Treatment of carcinoma of unknown primary site (CUP) directed by molecular profiling diagnosis: a prospective, phase II trial. J Clin Oncol 28
-
(2010)
J Clin Oncol
, vol.28
-
-
Hainsworth, J.D.1
Spigel, D.R.2
Rubin, M.S.3
Boccia, R.V.4
Fox, E.P.5
Firdaus, I.6
Erlander, M.G.7
Schnabel, C.8
Greco, F.A.9
-
19
-
-
0034674896
-
Chromosome 19 translocation, overexpression of Notch3, and human lung cancer
-
Dang TP, Gazdar AF, Virmani AK, Sepetavec T, Hande KR, Minna JD, Roberts JR, Carbone DP (2000) Chromosome 19 translocation, overexpression of Notch3, and human lung cancer. J Natl Cancer Inst 92:1355-1357
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1355-1357
-
-
Dang, T.P.1
Gazdar, A.F.2
Virmani, A.K.3
Sepetavec, T.4
Hande, K.R.5
Minna, J.D.6
Roberts, J.R.7
Carbone, D.P.8
-
20
-
-
18144426777
-
Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers
-
Haruki N, Kawaguchi KS, Eichenberger S, Massion PP, Olson S, Gonzalez A, Carbone DP, Dang TP (2005) Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers. Cancer Res 65: 3555-3561
-
(2005)
Cancer Res
, vol.65
, pp. 3555-3561
-
-
Haruki, N.1
Kawaguchi, K.S.2
Eichenberger, S.3
Massion, P.P.4
Olson, S.5
Gonzalez, A.6
Carbone, D.P.7
Dang, T.P.8
-
22
-
-
76549084826
-
Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor
-
Harrison H, Farnie G, Howell SJ, Rock RE, Stylianou S, Brennan KR, Bundred NJ, Clarke RB (2010) Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor. Cancer Res 70:709-718
-
(2010)
Cancer Res
, vol.70
, pp. 709-718
-
-
Harrison, H.1
Farnie, G.2
Howell, S.J.3
Rock, R.E.4
Stylianou, S.5
Brennan, K.R.6
Bundred, N.J.7
Clarke, R.B.8
-
23
-
-
77954635026
-
Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion
-
Grugan KD, Miller CG, Yao Y, Michaylira CZ, Ohashi S, Klein-Szanto AJ, Diehl JA, Herlyn M, Han M, Nakagawa H, Rustgi AK (2010) Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion. Proc Natl Acad Sci USA 107:11026-11031
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 11026-11031
-
-
Grugan, K.D.1
Miller, C.G.2
Yao, Y.3
Michaylira, C.Z.4
Ohashi, S.5
Klein-Szanto, A.J.6
Diehl, J.A.7
Herlyn, M.8
Han, M.9
Nakagawa, H.10
Rustgi, A.K.11
-
24
-
-
66149135285
-
The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma
-
Seiwert TY, Jagadeeswaran R, Faoro L, Janamanchi V, Nallasura V, El Dinali M, Yala S, Kanteti R, Cohen EE, Lingen MW, Martin L, Krishnaswamy S, Klein-Szanto A, Christensen JG, Vokes EE, Salgia R (2009) The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma. Cancer Res 69:3021-3031
-
(2009)
Cancer Res
, vol.69
, pp. 3021-3031
-
-
Seiwert, T.Y.1
Jagadeeswaran, R.2
Faoro, L.3
Janamanchi, V.4
Nallasura, V.5
El Dinali, M.6
Yala, S.7
Kanteti, R.8
Cohen, E.E.9
Lingen, M.W.10
Martin, L.11
Krishnaswamy, S.12
Klein-Szanto, A.13
Christensen, J.G.14
Vokes, E.E.15
Salgia, R.16
-
25
-
-
34249051970
-
Change of E-cadherin by hepatocyte growth factor and effects on the prognosis of hypopharyngeal carcinoma
-
Kim CH, Kim J, Kahng H, Choi EC (2007) Change of E-cadherin by hepatocyte growth factor and effects on the prognosis of hypopharyngeal carcinoma. Ann Surg Oncol 14:1565-1574
-
(2007)
Ann Surg Oncol
, vol.14
, pp. 1565-1574
-
-
Kim, C.H.1
Kim, J.2
Kahng, H.3
Choi, E.C.4
-
26
-
-
78651273473
-
Expression of integrin-linked kinase in lung squamous cell carcinoma and adenocarcinoma: Correlation with E-cadherin expression, tumor microvessel density and clinical outcome
-
Yu J, Shi R, Zhang D, Wang E, Qiu X (2011) Expression of integrin-linked kinase in lung squamous cell carcinoma and adenocarcinoma: correlation with E-cadherin expression, tumor microvessel density and clinical outcome. Virchows Arch 458: 99-107
-
(2011)
Virchows Arch
, vol.458
, pp. 99-107
-
-
Yu, J.1
Shi, R.2
Zhang, D.3
Wang, E.4
Qiu, X.5
-
27
-
-
84860006878
-
Immunohistochemical study of the epithelial-mesenchy-mal transition phenotype in cancer of unknown primary: Incidence, correlations and prognostic utility
-
Stoyianni A, Goussia A, Pentheroudakis G, Siozopoulou V, Io-achim E, Krikelis D, Golfinopoulos V, Cervantes A, Bobos M, Fotsis T, Bellou S, Fountzilas G, Malamou-Mitsi V, Pavlidis N (2012) Immunohistochemical study of the epithelial-mesenchy-mal transition phenotype in cancer of unknown primary: incidence, correlations and prognostic utility. Anticancer Res
-
(2012)
Anticancer Res
-
-
Stoyianni, A.1
Goussia, A.2
Pentheroudakis, G.3
Siozopoulou, V.4
Io-Achim, E.5
Krikelis, D.6
Golfinopoulos, V.7
Cervantes, A.8
Bobos, M.9
Fotsis, T.10
Bellou, S.11
Fountzilas, G.12
Malamou-Mitsi, V.13
Pavlidis, N.14
-
28
-
-
0035175805
-
Profiling of differentially expressed cancer-related genes in esophageal squamous cell carcinoma (ESCC) using human cancer cDNA arrays: Overexpression of oncogene MET correlates with tumor differentiation in ESCC
-
Hu YC, Lam KY, Law S, Wong J, Srivastava G (2001) Profiling of differentially expressed cancer-related genes in esophageal squamous cell carcinoma (ESCC) using human cancer cDNA arrays: overexpression of oncogene MET correlates with tumor differentiation in ESCC. Clin Cancer Res 7:3519-3525
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3519-3525
-
-
Hu, Y.C.1
Lam, K.Y.2
Law, S.3
Wong, J.4
Srivastava, G.5
-
29
-
-
71949119399
-
PHA665752, a small-molecule inhibitor of c-Met, inhibits hepatocyte growth factor-stimulated migration and proliferation of c-Met-positive neuro-blastoma cells
-
Crosswell HE, Dasgupta A, Alvarado CS, Watt T, Christensen JG, De P, Durden DL, Findley HW (2009) PHA665752, a small-molecule inhibitor of c-Met, inhibits hepatocyte growth factor-stimulated migration and proliferation of c-Met-positive neuro-blastoma cells. BMC Cancer 9:411
-
(2009)
BMC Cancer
, vol.9
, pp. 411
-
-
Crosswell, H.E.1
Dasgupta, A.2
Alvarado, C.S.3
Watt, T.4
Christensen, J.G.5
De, P.6
Durden, D.L.7
Findley, H.W.8
-
30
-
-
78449281896
-
Tumorigenic and metastatic activity of human thyroid cancer stem cells
-
Todaro M, Iovino F, Eterno V, Cammareri P, Gambara G, Espina V, Gulotta G, Dieli F, Giordano S, De Maria R, Stassi G (2010) Tumorigenic and metastatic activity of human thyroid cancer stem cells. Cancer Res 70:8874-8885
-
(2010)
Cancer Res
, vol.70
, pp. 8874-8885
-
-
Todaro, M.1
Iovino, F.2
Eterno, V.3
Cammareri, P.4
Gambara, G.5
Espina, V.6
Gulotta, G.7
Dieli, F.8
Giordano, S.9
De Maria, R.10
Stassi, G.11
-
31
-
-
78650426144
-
MET mutations in cancers of unknown primary origin (CUPs
-
Stella GM, Benvenuti S, Gramaglia D, Scarpa A, Tomezzoli A, Cassoni P, Senetta R, Venesio T, Pozzi E, Bardelli A, Comoglio PM (2011) MET mutations in cancers of unknown primary origin (CUPs). Hum Mutat 32:44-50
-
(2011)
Hum Mutat
, vol.32
, pp. 44-50
-
-
Stella, G.M.1
Benvenuti, S.2
Gramaglia, D.3
Scarpa, A.4
Tomezzoli, A.5
Cassoni, P.6
Senetta, R.7
Venesio, T.8
Pozzi, E.9
Bardelli, A.10
Comoglio, P.M.11
-
32
-
-
0142259346
-
The role of Notch in tumorigenesis: Oncogene or tumour suppressor?
-
Radtke F, Raj K (2003) The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nat Rev Cancer 3:756-767
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 756-767
-
-
Radtke, F.1
Raj, K.2
-
33
-
-
23944506654
-
The love-hate relationship between Ras and Notch
-
Sundaram MV (2005) The love-hate relationship between Ras and Notch. Genes Dev 19:1825-1839
-
(2005)
Genes Dev
, vol.19
, pp. 1825-1839
-
-
Sundaram, M.V.1
-
34
-
-
55749102718
-
Activated p38-MAPK and gemcitabine sensitivity in recurrent ovarian cancer
-
Klotz R, Zeimet AG, Reimer D, Muller-Holzner E, Chamson M, Marth C (2008) Activated p38-MAPK and gemcitabine sensitivity in recurrent ovarian cancer. Anticancer Res 28:2975-2980
-
(2008)
Anticancer Res
, vol.28
, pp. 2975-2980
-
-
Klotz, R.1
Zeimet, A.G.2
Reimer, D.3
Muller-Holzner, E.4
Chamson, M.5
Marth, C.6
-
35
-
-
80755123221
-
Is there a role for IGF1R and c-MET pathways in resistance to cetuximab in metastatic colorectal cancer?
-
Inno A, Salvatore MD, Cenci T, Martini M, Orlandi A, Strippoli A, Ferrara AM, Bagala C, Cassano A, Larocca LM, Barone C (2011) Is there a role for IGF1R and c-MET pathways in resistance to cetuximab in metastatic colorectal cancer? Clin Colo-rectal Cancer 10:325-332
-
(2011)
Clin Colo-rectal Cancer
, vol.10
, pp. 325-332
-
-
Inno, A.1
Salvatore, M.D.2
Cenci, T.3
Martini, M.4
Orlandi, A.5
Strippoli, A.6
Ferrara, A.M.7
Bagala, C.8
Cassano, A.9
Larocca, L.M.10
Barone, C.11
-
36
-
-
77349109465
-
Expression of Stat3 and Notch1 is associated with cis-platin resistance in head and neck squamous cell carcinoma
-
Gu F, Ma Y, Zhang Z, Zhao J, Kobayashi H, Zhang L, Fu L (2010) Expression of Stat3 and Notch1 is associated with cis-platin resistance in head and neck squamous cell carcinoma. Oncol Rep 23:671-676
-
(2010)
Oncol Rep
, vol.23
, pp. 671-676
-
-
Gu, F.1
Ma, Y.2
Zhang, Z.3
Zhao, J.4
Kobayashi, H.5
Zhang, L.6
Fu, L.7
-
37
-
-
0036300987
-
Quality assurance in immunohis-tochemistry: Results of an interlaboratory trial involving 172 pathologists
-
Rudiger T, Hofler H, Kreipe HH, Nizze H, Pfeifer U, Stein H, Dallenbach FE, Fischer HP, Mengel M, von Wasielewski R, Muller-Hermelink HK (2002) Quality assurance in immunohis-tochemistry: results of an interlaboratory trial involving 172 pathologists. Am J Surg Pathol 26:873-882
-
(2002)
Am J Surg Pathol
, vol.26
, pp. 873-882
-
-
Rudiger, T.1
Hofler, H.2
Kreipe, H.H.3
Nizze, H.4
Pfeifer, U.5
Stein, H.6
Dallenbach, F.E.7
Fischer, H.P.8
Mengel, M.9
Von Wasielewski, R.10
Muller-Hermelink, H.K.11
|