메뉴 건너뛰기




Volumn 28, Issue 5 B, 2008, Pages 2975-2980

Activated p38-MAPK and gemcitabine sensitivity in recurrent ovarian cancer

Author keywords

Chemoresistance; Gemcitabine; Ovarian cancer; p38 MAPK

Indexed keywords

DOXORUBICIN; GEMCITABINE; MITOGEN ACTIVATED PROTEIN KINASE P38; TOPOTECAN; TREOSULFAN;

EID: 55749102718     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (36)
  • 1
    • 20844436316 scopus 로고    scopus 로고
    • Advances in the management of epithelial ovarian cancer
    • Berkenblit A and Cannistra SA: Advances in the management of epithelial ovarian cancer. J Reprod Med 50(6): 426-438, 2005.
    • (2005) J Reprod Med , vol.50 , Issue.6 , pp. 426-438
    • Berkenblit, A.1    Cannistra, S.A.2
  • 2
    • 33646802603 scopus 로고    scopus 로고
    • Molecular targets of ovarian carcinomas with acquired resistance to platinum/taxane chemotherapy
    • Kurzeder C, Sauer G and Deissler H: Molecular targets of ovarian carcinomas with acquired resistance to platinum/taxane chemotherapy. Curr Cancer Drug Target 6(3): 207-227, 2006.
    • (2006) Curr Cancer Drug Target , vol.6 , Issue.3 , pp. 207-227
    • Kurzeder, C.1    Sauer, G.2    Deissler, H.3
  • 3
    • 2942679356 scopus 로고    scopus 로고
    • Survival following the documentation of platinum and taxane resistance in ovarian cancer: A single institution experience involving multiple phase 2 clinical trials
    • Markman M, Webster K, Zanotti K, Peterson G, Kulp B and Belinson J: Survival following the documentation of platinum and taxane resistance in ovarian cancer: a single institution experience involving multiple phase 2 clinical trials. Gynecol Oncol 93: 699-701, 2004.
    • (2004) Gynecol Oncol , vol.93 , pp. 699-701
    • Markman, M.1    Webster, K.2    Zanotti, K.3    Peterson, G.4    Kulp, B.5    Belinson, J.6
  • 4
    • 18844438857 scopus 로고    scopus 로고
    • Gemcitabine monotherapy in recurrent ovarian cancer: From the bench to the clinic
    • Bookman MA: Gemcitabine monotherapy in recurrent ovarian cancer: from the bench to the clinic. Int J Gynecol Cancer 15(Suppl 1): 12-17, 2005.
    • (2005) Int J Gynecol Cancer , vol.15 , Issue.SUPPL. 1 , pp. 12-17
    • Bookman, M.A.1
  • 5
    • 33745994656 scopus 로고    scopus 로고
    • Combined PEG liposomal doxorubicin and gemcitabine are active and have acceptable toxicity in patients with platinum-refractory and -resistant ovarian cancer after previous platinum-taxane therapy: A phase II Austrian AGO study
    • Petru E, Angleitner-Boubenizek L, Reinthaller A, Deibl M, Zeimet AG, Vollger B, Stempfl A and Marth C: Combined PEG liposomal doxorubicin and gemcitabine are active and have acceptable toxicity in patients with platinum-refractory and -resistant ovarian cancer after previous platinum-taxane therapy: A phase II Austrian AGO study. Gynecol Oncol 102(2): 226-229, 2006.
    • (2006) Gynecol Oncol , vol.102 , Issue.2 , pp. 226-229
    • Petru, E.1    Angleitner-Boubenizek, L.2    Reinthaller, A.3    Deibl, M.4    Zeimet, A.G.5    Vollger, B.6    Stempfl, A.7    Marth, C.8
  • 6
    • 0036462584 scopus 로고    scopus 로고
    • Determinants of resistance to 2'-2'-difluorodeoxycytidine (gemcitabine)
    • Bergman AM, Pinedo HM and Peters GJ: Determinants of resistance to 2'-2'-difluorodeoxycytidine (gemcitabine). Drug Resist Update 5: 19-33, 2002.
    • (2002) Drug Resist Update , vol.5 , pp. 19-33
    • Bergman, A.M.1    Pinedo, H.M.2    Peters, G.J.3
  • 8
    • 0035805596 scopus 로고    scopus 로고
    • Akt, MAPK (ERK1/2), and p38 act in concert to promote apoptosis in response to ErbB receptor family inhibition
    • Nelson JM and Fry DW: Akt, MAPK (ERK1/2), and p38 act in concert to promote apoptosis in response to ErbB receptor family inhibition. J Biol Chem 276: 14842-14847, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 14842-14847
    • Nelson, J.M.1    Fry, D.W.2
  • 9
    • 2342562556 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in apoptosis regulation
    • Wada T and Penninger JM: Mitogen-activated protein kinases in apoptosis regulation. Oncogene 23: 2838-2849, 2004.
    • (2004) Oncogene , vol.23 , pp. 2838-2849
    • Wada, T.1    Penninger, J.M.2
  • 10
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson GL and Lapadat R: Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298: 1911-1912, 2002.
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 11
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang L and Karin M: Mammalian MAP kinase signalling cascades. Nature 410(6824): 37-40, 2001.
    • (2001) Nature , vol.410 , Issue.6824 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 12
    • 19644367000 scopus 로고    scopus 로고
    • Activation and signaling of the p38 MAP kinase pathway
    • Zarubin T and Han J: Activation and signaling of the p38 MAP kinase pathway. Cell Res 15(1): 11-18, 2005.
    • (2005) Cell Res , vol.15 , Issue.1 , pp. 11-18
    • Zarubin, T.1    Han, J.2
  • 13
    • 0034097798 scopus 로고    scopus 로고
    • MAP kinase pathways activated by stress: The p38 MAPK pathway
    • Obata T, Brown GE and Yaffe M: MAP kinase pathways activated by stress: The p38 MAPK pathway. Crit Care Med 28(Suppl 4): N67-77, 2000.
    • (2000) Crit Care Med , vol.28 , Issue.SUPPL. 4
    • Obata, T.1    Brown, G.E.2    Yaffe, M.3
  • 14
    • 34547154349 scopus 로고    scopus 로고
    • p38 MAP-Kinases pathway regulation, function and role in human diseases
    • Cuenda A and Rousseau S: p38 MAP-Kinases pathway regulation, function and role in human diseases. Biochim Biophys Acta 1773: 1358-1375, 2007.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 1358-1375
    • Cuenda, A.1    Rousseau, S.2
  • 15
    • 3042522892 scopus 로고    scopus 로고
    • Stress-activated protein kinases-tumor suppressors or tumor initiators?
    • Engelberg D: Stress-activated protein kinases-tumor suppressors or tumor initiators? Semin Cancer Biol 14(4): 271-282, 2004.
    • (2004) Semin Cancer Biol , vol.14 , Issue.4 , pp. 271-282
    • Engelberg, D.1
  • 16
    • 34547212349 scopus 로고    scopus 로고
    • The pathways to tumor suppression via route p38
    • Han J and Sun P: The pathways to tumor suppression via route p38. Trends Biochem Sci 32(8): 364-371, 2007.
    • (2007) Trends Biochem Sci , vol.32 , Issue.8 , pp. 364-371
    • Han, J.1    Sun, P.2
  • 17
    • 43649105389 scopus 로고    scopus 로고
    • Signal-dependent regulation of gene expression as a target for cancer treatment: Inhibiting p38a in colorectal tumors
    • Chiacchiera F and Simone C: Signal-dependent regulation of gene expression as a target for cancer treatment: Inhibiting p38a in colorectal tumors. Cancer Lett 265: 16-26, 2008.
    • (2008) Cancer Lett , vol.265 , pp. 16-26
    • Chiacchiera, F.1    Simone, C.2
  • 18
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia Z, Dickens M, Raingeaud J, Davis RJ and Greenberg ME: Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270(5240): 1326-1331, 1995.
    • (1995) Science , vol.270 , Issue.5240 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 19
    • 41549160315 scopus 로고    scopus 로고
    • Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival
    • Junttila MR, Li SP and Westermarck J: Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J 22(4): 954-965, 2008.
    • (2008) FASEB J , vol.22 , Issue.4 , pp. 954-965
    • Junttila, M.R.1    Li, S.P.2    Westermarck, J.3
  • 22
    • 18844425731 scopus 로고    scopus 로고
    • Review of gemcitabine-based combinations for platinum-resistant ovarian cancer
    • Sehouli J: Review of gemcitabine-based combinations for platinum-resistant ovarian cancer. Int J Gynecol Cancer 15(Suppl 1): 23-30, 2005.
    • (2005) Int J Gynecol Cancer , vol.15 , Issue.SUPPL. 1 , pp. 23-30
    • Sehouli, J.1
  • 23
    • 0032910168 scopus 로고    scopus 로고
    • Organization and regulation of mitogen-activated protein kinase signalling pathways
    • Garrington TP and Johnson GL: Organization and regulation of mitogen-activated protein kinase signalling pathways. Curr Opin Cell Biol 11: 211-218, 1999.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 211-218
    • Garrington, T.P.1    Johnson, G.L.2
  • 24
    • 42949102509 scopus 로고    scopus 로고
    • The p38 MAPK stress pathway as a tumor suppressor or more?
    • Loesch M and Chen G: The p38 MAPK stress pathway as a tumor suppressor or more? Front Biosci 13: 3581-3593, 2008.
    • (2008) Front Biosci , vol.13 , pp. 3581-3593
    • Loesch, M.1    Chen, G.2
  • 25
    • 0034910880 scopus 로고    scopus 로고
    • Profiling of protein kinases in the neoplastic transformation of human ovarian surface epithelium
    • Wong AST, Kim SO, Leung PCK, Auersperg N and Pelech SL: Profiling of protein kinases in the neoplastic transformation of human ovarian surface epithelium. Gynecol Oncol 82: 305-311, 2001.
    • (2001) Gynecol Oncol , vol.82 , pp. 305-311
    • Wong, A.S.T.1    Kim, S.O.2    Leung, P.C.K.3    Auersperg, N.4    Pelech, S.L.5
  • 26
    • 13544271958 scopus 로고    scopus 로고
    • Increased expression of mitogen-activated protein kinase and its upstream regulating signal in human gastric cancer
    • Liang B, Wang S, Zhu XG, Yu YX, Cui ZR and Yu YZ: Increased expression of mitogen-activated protein kinase and its upstream regulating signal in human gastric cancer. World J Gastroenterol 11(5): 623-628, 2005.
    • (2005) World J Gastroenterol , vol.11 , Issue.5 , pp. 623-628
    • Liang, B.1    Wang, S.2    Zhu, X.G.3    Yu, Y.X.4    Cui, Z.R.5    Yu, Y.Z.6
  • 27
    • 0034806972 scopus 로고    scopus 로고
    • Enhanced ROS production in oncogenically transformed cells potentiates C-Jun N-terminal kinase and p38 mitogen-activated protein kinase
    • Benhar M, Dalyot I, Engelberg D and Levitzki A: Enhanced ROS production in oncogenically transformed cells potentiates C-Jun N-terminal kinase and p38 mitogen-activated protein kinase. Mol Cell Biol 21(20): 6913-6926, 2001.
    • (2001) Mol Cell Biol , vol.21 , Issue.20 , pp. 6913-6926
    • Benhar, M.1    Dalyot, I.2    Engelberg, D.3    Levitzki, A.4
  • 28
    • 0038482086 scopus 로고    scopus 로고
    • Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells
    • Mansouri A, Ridgway LD, Korapati AL, Zhang Q, Tian L, Wang Y, Siddik ZH, Mills GB and Claret FX: Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells. J Biol Chem 278: 19245-19256, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 19245-19256
    • Mansouri, A.1    Ridgway, L.D.2    Korapati, A.L.3    Zhang, Q.4    Tian, L.5    Wang, Y.6    Siddik, Z.H.7    Mills, G.B.8    Claret, F.X.9
  • 34
    • 0035425774 scopus 로고    scopus 로고
    • The role of ERK 1/2 and p38 MAP-kinase pathways in taxol-induced apoptosis in human ovarian carcinoma cells
    • Seidman R, Gitelman I, Sagi O, Horwitz SB and Wolfson M: The role of ERK 1/2 and p38 MAP-kinase pathways in taxol-induced apoptosis in human ovarian carcinoma cells. Exp Cell Research 265: 84-92, 2001.
    • (2001) Exp Cell Research , vol.265 , pp. 84-92
    • Seidman, R.1    Gitelman, I.2    Sagi, O.3    Horwitz, S.B.4    Wolfson, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.