Novel survivin inhibitor YM155 elicits cytotoxicity in glioblastoma cell lines with normal or deficiency DNA-dependent protein kinase activity

Pediatrics and Neonatology

Volumn 53, Issue 3, 2012, Pages 199-204

  Lai, Pei Chun ^a,b   Chen, Shu Huey ^a,b   Yang, Shang Hsien ^a,b   Cheng, Chuan Chu ^b   Chiu, Ted H ^a   Huang, Yen Ta ^a,b  

^a TZU CHI UNIVERSITY   (Taiwan)

^b BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

Author keywords

DNA dependent protein kinase; glioblastoma; securin; surviving; YM155

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALPHA TUBULIN; DNA DEPENDENT PROTEIN KINASE; SECURIN; SEPANTRONIUM BROMIDE; SURVIVIN;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DNA FRAGMENTATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GLIOBLASTOMA; HUMAN; HUMAN CELL; IC 50; PROTEIN EXPRESSION; WESTERN BLOTTING;

APOPTOSIS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; DNA-ACTIVATED PROTEIN KINASE; GLIOBLASTOMA; HUMANS; IMIDAZOLES; INHIBITOR OF APOPTOSIS PROTEINS; NAPHTHOQUINONES; NEOPLASM PROTEINS;

EID: 84863631297     PISSN: 18759572     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pedneo.2012.04.008     Document Type: Article

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