Nigericin-induced impairment of autophagic flux in neuronal cells is inhibited by overexpression of Bak

Journal of Biological Chemistry

Volumn 287, Issue 28, 2012, Pages 23271-23282

  Lim, Junghyun ^a   Lee, Yunsu ^a   Kim, Hyun Wook ^b   Rhyu, Im Joo ^b   Oh, Myung Sook ^c   Youdim, Moussa B H ^d   Yue, Zhenyu ^e   Oh, Young J ^a  

^a Yonsei University   (South Korea)

^b Korea University College of Medicine   (South Korea)

^c Kyung Hee University   (South Korea)

^d TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY; BCL-2 FAMILY PROTEINS; CASPASE-3; CASPASES; CELL LINES; MICROSCOPIC STUDY; NEURONAL CELL; NIGERICIN; OVER-EXPRESSION; REGULATORY EFFECTS;

CELL CULTURE; CELL DEATH; DEGRADATION; NEURONS; ORGANIC COMPOUNDS; TISSUE;

IONOPHORES;

BIOLOGICAL MARKER; CASPASE; LC3 II PROTEIN; NIGERICIN; PROTEIN BAK; PROTEIN P62; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGY; CELL ULTRASTRUCTURE; CELL VACUOLE; CONTROLLED STUDY; NERVE CELL; NERVE CELL NECROSIS; NERVE DEGENERATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; REGULATORY MECHANISM;

ANIMALS; APOPTOSIS; AUTOPHAGY; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; CELL LINE; CELL LINE, TUMOR; CELLS, CULTURED; CHLOROQUINE; EMBRYO, MAMMALIAN; FIBROBLASTS; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; MICE; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MICROTUBULE-ASSOCIATED PROTEINS; MONENSIN; NEURONS; NIGERICIN; PROTON IONOPHORES; RNA INTERFERENCE; VACUOLES;

EID: 84863617809     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.364281     Document Type: Article

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