Hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5) communicates cellular iron and oxygen availability by distinct mechanisms

Journal of Biological Chemistry

Volumn 287, Issue 28, 2012, Pages 23710-23717

  Chollangi, Srinivas ^a   Thompson, Joel W ^a   Ruiz, Julio C ^a   Gardner, Kevin H ^a   Bruick, Richard K ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR ENVIRONMENT; CONFORMATIONAL CHANGE; DIFFERENTIAL STABILITY; DYNAMIC SENSOR; IRON HOMEOSTASIS; IRON REGULATORY PROTEINS; IRON UPTAKE; LEUCINE-RICH REPEATS; MAMMALIAN CELLS; OXYGEN DEPLETION; PROTEASOMAL DEGRADATION; SENSING MECHANISM; STRUCTURAL CHANGE; UBIQUITIN LIGASES;

AMINO ACIDS; DEGRADATION; IRON; OXYGEN; PROTEINS;

IRON COMPOUNDS;

F BOX AND LEUCINE RICH REPEAT PROTEIN 5; F BOX PROTEIN; HEMERYTHRIN; IRON; OXYGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOSENSOR; CELL LEVEL; CONTROLLED STUDY; HOMEOSTASIS; MAMMAL CELL; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OXYGEN SENSING; PREDICTION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

3T3 CELLS; ANIMALS; BINDING SITES; CIRCULAR DICHROISM; CYSTEINE PROTEINASE INHIBITORS; F-BOX PROTEINS; HEK293 CELLS; HEMERYTHRIN; HUMANS; IMMUNOBLOTTING; IRON; LEUPEPTINS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED BALB C; OXYGEN; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; UBIQUITIN-PROTEIN LIGASES;

MAMMALIA;

EID: 84863614610     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.360404     Document Type: Article

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