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Volumn 97, Issue 7, 2012, Pages

Androgens inhibit the stimulatory action of 17β-estradiol on normal human breast tissue in explant cultures

Author keywords

[No Author keywords available]

Indexed keywords

17BETA HYDROXY 3 OXO 4 ANDROSTENE; AMPHIREGULIN; ANDROGEN; ANDROGEN RECEPTOR; ANDROSTANOLONE; APOLIPOPROTEIN D; BICALUTAMIDE; CYCLIN D1; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FULVESTRANT; MESSENGER RNA; PROSTATE SPECIFIC ANTIGEN; STEROID RECEPTOR; TESTOSTERONE; TREFOIL FACTOR 1; UNCLASSIFIED DRUG;

EID: 84863597131     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-3228     Document Type: Article
Times cited : (32)

References (41)
  • 1
    • 33745728370 scopus 로고    scopus 로고
    • Dehydroepiandrosterone, androgens and the mammary gland
    • DOI 10.1080/09513590600624440, PII M14789033N58826J
    • Labrie F 2006 Dehydroepiandrosterone, androgens and the mammary gland. Gynecol Endocrinol 22:118-130 (Pubitemid 43995028)
    • (2006) Gynecological Endocrinology , vol.22 , Issue.3 , pp. 118-130
    • Labrie, F.1
  • 3
  • 4
    • 11444264897 scopus 로고    scopus 로고
    • Endogenous estrogen, androgen, and progesterone concentrations and breast cancer risk among postmenopausal women
    • DOI 10.1093/jnci/djh336
    • Missmer SA, Eliassen AH, Barbieri RL, Hankinson SE 2004 Endogenous estrogen, androgen, and progesterone concentrations and breast cancer risk among postmenopausal women. J Natl Cancer Inst 96:1856-1865 (Pubitemid 40081323)
    • (2004) Journal of the National Cancer Institute , vol.96 , Issue.24 , pp. 1856-1865
    • Missmer, S.A.1    Eliassen, A.H.2    Barbieri, R.L.3    Hankinson, S.E.4
  • 5
    • 0024269969 scopus 로고
    • Stimulatory effects of androgen and antiandrogen on the in vitro proliferation of human mammary carcinoma cells
    • DOI 10.1007/BF00398183
    • Hackenberg R, Hofmann J, Hölzel F, Schulz KD 1988 Stimulatory effects of androgen and antiandrogen on the in vitro proliferation of human mammary carcinoma cells. J Cancer Res Clin Oncol 114:593-601 (Pubitemid 19011676)
    • (1988) Journal of Cancer Research and Clinical Oncology , vol.114 , Issue.6 , pp. 593-601
    • Hackenberg, R.1    Hofmann, J.2    Holzel, F.3    Schulz, K.-D.4
  • 7
    • 79960989401 scopus 로고    scopus 로고
    • Androgen receptor expression is significantly associated with better outcomes in estrogen receptor-positive breast cancers
    • Park S, Koo JS, Kim MS, Park HS, Lee JS, Lee JS, Kim SI, Park BW, Lee KS 2011 Androgen receptor expression is significantly associated with better outcomes in estrogen receptor-positive breast cancers. Ann Oncol 22:1755-1762
    • (2011) Ann Oncol , vol.22 , pp. 1755-1762
    • Park, S.1    Koo, J.S.2    Kim, M.S.3    Park, H.S.4    Lee, J.S.5    Lee, J.S.6    Kim, S.I.7    Park, B.W.8    Lee, K.S.9
  • 8
    • 33747886393 scopus 로고    scopus 로고
    • Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole
    • DOI 10.1158/0008-5472.CAN-05-3984
    • Macedo LF, Guo Z, Tilghman SL, Sabnis GJ, Qiu Y, Brodie A 2006 Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole. Cancer Res 66:7775-7782 (Pubitemid 44289238)
    • (2006) Cancer Research , vol.66 , Issue.15 , pp. 7775-7782
    • Macedo, L.F.1    Guo, Z.2    Tilghman, S.L.3    Sabnis, G.J.4    Qiu, Y.5    Brodie, A.6
  • 10
    • 2942670633 scopus 로고    scopus 로고
    • Testosterone effects on the breast: Implications for testosterone therapy for women
    • DOI 10.1210/er.2003-0016
    • Somboonporn W, Davis SR 2004 Testosterone effects on the breast: implications for testosterone therapy for women. Endocr Rev 25:374-388 (Pubitemid 38780666)
    • (2004) Endocrine Reviews , vol.25 , Issue.3 , pp. 374-388
    • Somboonporn, W.1    Davis, S.R.2
  • 11
    • 0033818180 scopus 로고    scopus 로고
    • Testosterone inhibits estrogen-induced mammary epithelial proliferation and suppresses estrogen receptor expression
    • Zhou J, Ng S, Adesanya-Famuiya O, Anderson K, Bondy CA 2000 Testosterone inhibits estrogen-induced mammary epithelial proliferation and suppresses estrogen receptor expression. FASEB J 14:1725-1730
    • (2000) FASEB J , vol.14 , pp. 1725-1730
    • Zhou, J.1    Ng, S.2    Adesanya-Famuiya, O.3    Anderson, K.4    Bondy, C.A.5
  • 13
    • 33750697301 scopus 로고    scopus 로고
    • Effects of estradiol and medroxyprogesterone acetate on morphology, proliferation and apoptosis of human breast tissue in organ cultures
    • Eigeliene N, Härkönen P, Erkkola R 2006 Effects of estradiol and medroxyprogesterone acetate on morphology, proliferation and apoptosis of human breast tissue in organ cultures.BMCCancer 6:246
    • (2006) BMCCancer , vol.6 , pp. 246
    • Eigeliene, N.1    Härkönen, P.2    Erkkola, R.3
  • 15
    • 68349100033 scopus 로고    scopus 로고
    • Normal breast tissue implanted into athymic nude mice identifies biomarkers of the effects of human pregnancy levels of estrogen
    • Phila
    • Blance RN, Sims AH, Anderson E, Howell A, Clarke RB 2009 Normal breast tissue implanted into athymic nude mice identifies biomarkers of the effects of human pregnancy levels of estrogen. Cancer Prev Res (Phila) 2:257-264
    • (2009) Cancer Prev Res , vol.2 , pp. 257-264
    • Blance, R.N.1    Sims, A.H.2    Anderson, E.3    Howell, A.4    Clarke, R.B.5
  • 18
    • 33745106870 scopus 로고    scopus 로고
    • Effects of oestrogen on gene expression in epithelium and stroma of normal human breast tissue
    • DOI 10.1677/erc.1.01165
    • Wilson CL, Sims AH, Howell A, Miller CJ, Clarke RB 2006 Effects of oestrogen on gene expression in epithelium and stroma of normal human breast tissue. Endocr Relat Cancer 13:617-628 (Pubitemid 43886681)
    • (2006) Endocrine-Related Cancer , vol.13 , Issue.2 , pp. 617-628
    • Wilson, C.L.1    Sims, A.H.2    Howell, A.3    Miller, C.J.4    Clarke, R.B.5
  • 19
    • 10344247660 scopus 로고    scopus 로고
    • Expression of Prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) in ileum and other extraprostatic tissues
    • DOI 10.1002/ijc.20605
    • Olsson AY, Bjartell A, Lilja H, Lundwall A 2005 Expression of prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) in ileum and other extraprostatic tissues. Int J Cancer 113:290-297 (Pubitemid 39628320)
    • (2005) International Journal of Cancer , vol.113 , Issue.2 , pp. 290-297
    • Olsson, A.Y.1    Bjartell, A.2    Lilja, H.3    Lundwall, A.4
  • 21
    • 33746102558 scopus 로고    scopus 로고
    • Fulvestrant (ICI 182,780) down-regulates androgen receptor expression and diminishes androgenic responses in LNCaP human prostate cancer cells
    • DOI 10.1158/1535-7163.MCT-06-0065
    • Bhattacharyya RS, Krishnan AV, Swami S, Feldman D 2006 Fulvestrant (ICI 182,780) down-regulates androgen receptor expression and diminishes androgenic responses in LNCaP human prostate cancer cells. Mol Cancer Ther 5:1539-1549 (Pubitemid 44070491)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.6 , pp. 1539-1549
    • Bhattacharyya, R.S.1    Krishnan, A.V.2    Swami, S.3    Feldman, D.4
  • 22
    • 82355163442 scopus 로고    scopus 로고
    • Minireview: Recent advances in extranuclear steroid receptor actions
    • Hammes SR, Levin ER 2011 Minireview: recent advances in extranuclear steroid receptor actions. Endocrinology 152:4489-4495
    • (2011) Endocrinology , vol.152 , pp. 4489-4495
    • Hammes, S.R.1    Levin, E.R.2
  • 24
    • 0036242843 scopus 로고    scopus 로고
    • Androgens and mammary growth and neoplasia
    • PII S0015028202029795
    • Dimitrakakis C, Zhou J, Bondy CA 2002 Androgens and mammary growth and neoplasia. Fertil Steril 77(Suppl 4):S26-S33 (Pubitemid 34465841)
    • (2002) Fertility and Sterility , vol.77 , Issue.SUPPL. 4
    • Dimitrakakis, C.1    Zhou, J.2    Bondy, C.A.3
  • 27
    • 8644236707 scopus 로고    scopus 로고
    • Postmenopausal testosterone therapy and breast cancer risk
    • DOI 10.1016/j.maturitas.2004.06.020, PII S0378512204002245
    • Somboonporn W, Davis SR 2004 Postmenopausal testosterone therapy and breast cancer risk. Maturitas 49:267-275 (Pubitemid 39505180)
    • (2004) Maturitas , vol.49 , Issue.4 , pp. 267-275
    • Somboonporn, W.1    Davis, S.R.2
  • 28
    • 0024264118 scopus 로고
    • Androgens inhibit basal and estrogen-induced cell proliferation in the ZR-75-1 human breast cancer cell line
    • DOI 10.1007/BF01805942
    • Poulin R, Baker D, Labrie F 1988 Androgens inhibit basal and estrogen-induced cell proliferation in the ZR-75-1 human breast cancer cell line. Breast Cancer Res Treat 12:213-225 (Pubitemid 19019103)
    • (1988) Breast Cancer Research and Treatment , vol.12 , Issue.2 , pp. 213-225
    • Poulin, R.1    Baker, D.2    Labrie, F.3
  • 29
    • 34247643957 scopus 로고    scopus 로고
    • Testosterone inhibits estrogen/progestogen-induced breast cell proliferation in postmenopausal women
    • DOI 10.1097/01.gme.0000232033.92411.51
    • Hofling M, Hirschberg AL, Skoog L, Tani E, Hagerström T, von Schoultz B 2007 Testosterone inhibits estrogen/progestogen-induced breast cell proliferation in postmenopausal women. Menopause 14:183-190 (Pubitemid 46673468)
    • (2007) Menopause , vol.14 , Issue.2 , pp. 183-190
    • Hofling, M.1    Hirschberg, A.L.2    Skoog, L.3    Tani, E.4    Hagerstrom, T.5    Von Schoultz, B.6
  • 33
    • 0032894681 scopus 로고    scopus 로고
    • Androgens down-regulate bcl-2 protooncogene expression in ZR-75-1 human breast cancer cells
    • DOI 10.1210/en.140.1.416
    • Lapointe J, Fournier A, Richard V, Labrie C 1999 Androgens down-regulate bcl-2 protooncogene expression in ZR-75-1 human breast cancer cells. Endocrinology 140:416-421 (Pubitemid 29011187)
    • (1999) Endocrinology , vol.140 , Issue.1 , pp. 416-421
    • Lapointe, J.1    Fournier, A.2    Richard, V.3    Labrie, C.4
  • 34
    • 80053135925 scopus 로고    scopus 로고
    • Differential effects of exogenous androgen and an androgen receptor antagonist in the peri- and postpubertal murine mammary gland
    • Peters AA, Ingman WV, Tilley WD, Butler LM 2011 Differential effects of exogenous androgen and an androgen receptor antagonist in the peri- and postpubertal murine mammary gland. Endocrinology 152:3728-3737
    • (2011) Endocrinology , vol.152 , pp. 3728-3737
    • Peters, A.A.1    Ingman, W.V.2    Tilley, W.D.3    Butler, L.M.4
  • 35
    • 0037989013 scopus 로고    scopus 로고
    • Extragonadal synthesis of sex steroids: Intracrinology
    • Labrie F 2003 Extragonadal synthesis of sex steroids: intracrinology. Ann Endocrinol (Paris) 64:95-107 (Pubitemid 36565163)
    • (2003) Annales d'Endocrinologie , vol.64 , Issue.2 , pp. 95-107
    • Labrie, F.1
  • 36
    • 0037396439 scopus 로고    scopus 로고
    • Endocrine and intracrine sources of androgens in women: Inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone
    • DOI 10.1210/er.2001-0031
    • Labrie F, Luu-The V, Labrie C, Bélanger A, Simard J, Lin SX, Pelletier G 2003 Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. Endocr Rev 24:152-182 (Pubitemid 36515283)
    • (2003) Endocrine Reviews , vol.24 , Issue.2 , pp. 152-182
    • Labrie, F.1    Luu-The, V.2    Labrie, C.3    Belanger, A.4    Simard, J.5    Lin, S.-X.6    Pelletier, G.7
  • 38
    • 0030670385 scopus 로고    scopus 로고
    • Dissociation between steroid receptor expression and cell proliferation in the human breast
    • Clarke RB, Howell A, Potten CS, Anderson E 1997 Dissociation between steroid receptor expression and cell proliferation in the human breast. Cancer Res 57:4987-4991 (Pubitemid 27498105)
    • (1997) Cancer Research , vol.57 , Issue.22 , pp. 4987-4991
    • Clarke, R.B.1    Howell, A.2    Potten, C.S.3    Anderson, E.4
  • 39
    • 0034735853 scopus 로고    scopus 로고
    • Estrogen receptor beta in the breast: Role in estrogen responsiveness and development of breast cancer
    • DOI 10.1016/S0960-0760(00)00130-8, PII S0960076000001308
    • Gustafsson JA, Warner M 2000 Estrogen receptor beta in the breast: role in estrogen responsiveness and development of breast cancer. J Steroid Biochem Mol Biol 74:245-248 (Pubitemid 32140403)
    • (2000) Journal of Steroid Biochemistry and Molecular Biology , vol.74 , Issue.5 , pp. 245-248
    • Gustafsson, J.-A.1    Warner, M.2
  • 41
    • 40449122270 scopus 로고    scopus 로고
    • Sex hormone receptors and testosterone in postmenopausal women
    • DOI 10.1097/gme.0b013e3181614317, PII 0004219220081502000002
    • Bentov Y, Casper RF 2008 Sex hormone receptors and testosterone in postmenopausal women. Menopause 15:210-211 (Pubitemid 351354976)
    • (2008) Menopause , vol.15 , Issue.2 , pp. 210-211
    • Bentov, Y.1    Casper, R.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.