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Volumn 27, Issue 8, 2012, Pages 445-452

The effects of ammonium perchlorate on thyroid homeostasis and thyroid-specific gene expression in rat

Author keywords

Perchlorate; Sodium iodide symporter; Thyroglobulin; Thyroid homeostasis; Thyroid specific gene; Thyroperoxidase

Indexed keywords

AMMONIUM PERCHLORATES; BODY WEIGHT; COMPETITIVE INHIBITION; DEFENSE INDUSTRY; HIGH DOSE; IODIDE UPTAKE; PERCHLORATE; THYROGLOBULIN; THYROID GLANDS; THYROID HOMEOSTASIS; THYROID HORMONES; THYROPEROXIDASE;

EID: 84863576638     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20655     Document Type: Article
Times cited : (24)

References (51)
  • 1
    • 58149282918 scopus 로고    scopus 로고
    • Agency for Toxic Substances and Disease Registry (ATSDR). Atlanta, GA: US Department of Health and Human Services, Public Health Service
    • Agency for Toxic Substances and Disease Registry (ATSDR). 2008. Toxicological Profile for Perchlorates. Atlanta, GA: US Department of Health and Human Services, Public Health Service. pp 153-154. Available at:
    • (2008) Toxicological Profile for Perchlorates , pp. 153-154
  • 3
    • 33845317579 scopus 로고    scopus 로고
    • Urinary perchlorate and thyroid hormone levels in adolescent and adult men and women living in the United States
    • Blount BC, Pirkle JL, Osterloh JD, Valentin-Blasini L, Caldwell KL. 2006. Urinary perchlorate and thyroid hormone levels in adolescent and adult men and women living in the United States. Environ Health Perspect 114: 1865-1871.
    • (2006) Environ Health Perspect , vol.114 , pp. 1865-1871
    • Blount, B.C.1    Pirkle, J.L.2    Osterloh, J.D.3    Valentin-Blasini, L.4    Caldwell, K.L.5
  • 4
    • 0028319737 scopus 로고
    • Mechanisms of chemical injury of thyroid gland
    • Capen CC. 1994. Mechanisms of chemical injury of thyroid gland. Prog Clin Biol Res 387: 173-191.
    • (1994) Prog Clin Biol Res , vol.387 , pp. 173-191
    • Capen, C.C.1
  • 5
    • 0031053510 scopus 로고    scopus 로고
    • Mechanistic data and risk assessment of selected toxic endpoints of the thyroid gland
    • Capen CC. 1997. Mechanistic data and risk assessment of selected toxic endpoints of the thyroid gland. Toxicol Pathol 25: 39-48.
    • (1997) Toxicol Pathol , vol.25 , pp. 39-48
    • Capen, C.C.1
  • 6
    • 0032422631 scopus 로고    scopus 로고
    • Correlation of mechanistic data and histopathology in the evaluation of selected toxic endpoints of the endocrine system
    • Capen CC. 1998. Correlation of mechanistic data and histopathology in the evaluation of selected toxic endpoints of the endocrine system. Toxicol Lett 102/103: 405-409.
    • (1998) Toxicol Lett , vol.102-103 , pp. 405-409
    • Capen, C.C.1
  • 7
    • 0027288003 scopus 로고
    • Iodide transport in the thyroid gland
    • 1154
    • Carrasco N. 1993. Iodide transport in the thyroid gland. Biochim Biophys Acta 1154: 65-82.
    • (1993) Biochim Biophys Acta , pp. 65-82
    • Carrasco, N.1
  • 8
    • 0023611379 scopus 로고
    • Thyrotropin stimulation of cultured thyroid cells increases steady state levels of the messenger ribonucleic acid for thyroid peroxidase
    • Chazenbalk G, Magnusson RP, Rapoport B. 1987. Thyrotropin stimulation of cultured thyroid cells increases steady state levels of the messenger ribonucleic acid for thyroid peroxidase. Mol Endocrinol 1: 913-917.
    • (1987) Mol Endocrinol , vol.1 , pp. 913-917
    • Chazenbalk, G.1    Magnusson, R.P.2    Rapoport, B.3
  • 9
    • 55549120181 scopus 로고    scopus 로고
    • Effects of maternal exposure to ammonium perchlorate on thyroid function and the expression of thyroid-responsive genes in Japanese quail embryos
    • Chen Y, Sible JC, McNabb FM. 2008. Effects of maternal exposure to ammonium perchlorate on thyroid function and the expression of thyroid-responsive genes in Japanese quail embryos. Gen Comp Endocrinol 159: 196-207.
    • (2008) Gen Comp Endocrinol , vol.159 , pp. 196-207
    • Chen, Y.1    Sible, J.C.2    McNabb, F.M.3
  • 10
    • 77049095577 scopus 로고    scopus 로고
    • Perchlorate transport and inhibition of the sodium iodide symporter measured with the yellow fluorescent protein variant YFP-H148Q/I152L
    • Cianchetta S, Bernardo JD, Romeo G, Rhoden KJ. 2010. Perchlorate transport and inhibition of the sodium iodide symporter measured with the yellow fluorescent protein variant YFP-H148Q/I152L. Toxicol Appl Pharmacol 243: 372-380.
    • (2010) Toxicol Appl Pharmacol , vol.243 , pp. 372-380
    • Cianchetta, S.1    Bernardo, J.D.2    Romeo, G.3    Rhoden, K.J.4
  • 11
    • 33746283468 scopus 로고    scopus 로고
    • Perchlorate versus other environmental sodium/iodide symporter inhibitors: Potential thyroid-related health effects
    • De Groef B, Decallonne BR, Geyten SV, Darras VM, Bouillon R. 2006. Perchlorate versus other environmental sodium/iodide symporter inhibitors: Potential thyroid-related health effects. Eur J Endocrinol 155: 17-25.
    • (2006) Eur J Endocrinol , vol.155 , pp. 17-25
    • De Groef, B.1    Decallonne, B.R.2    Geyten, S.V.3    Darras, V.M.4    Bouillon, R.5
  • 13
    • 0024814832 scopus 로고
    • Control of thyroperoxidase and thyroglobulin transcription by cAMP: Evidence for distinct regulatory mechanisms
    • Gerard CM, Lefort A, Christophe D, Libert F, Van Sande J, Dumont JE, Vassart G. 1989. Control of thyroperoxidase and thyroglobulin transcription by cAMP: Evidence for distinct regulatory mechanisms. Mol Endocrinol 3: 2110-2118.
    • (1989) Mol Endocrinol , vol.3 , pp. 2110-2118
    • Gerard, C.M.1    Lefort, A.2    Christophe, D.3    Libert, F.4    Van Sande, J.5    Dumont, J.E.6    Vassart, G.7
  • 14
    • 31544433721 scopus 로고    scopus 로고
    • A comparative toxicological assessment of perchlorate and thiocyanate based on competitive inhibition of iodide uptake as the common mode of action
    • Gibbs JP. 2006. A comparative toxicological assessment of perchlorate and thiocyanate based on competitive inhibition of iodide uptake as the common mode of action. Hum Ecol Risk Assess 12: 157-173.
    • (2006) Hum Ecol Risk Assess , vol.12 , pp. 157-173
    • Gibbs, J.P.1
  • 15
    • 0013934653 scopus 로고
    • Effects of thiocyanate, perchlorate and other anions on thyroidal iodine metabolism
    • Greer MA, Stott AK, Milne KA. 1966. Effects of thiocyanate, perchlorate and other anions on thyroidal iodine metabolism. Endocrinology 79: 237-247.
    • (1966) Endocrinology , vol.79 , pp. 237-247
    • Greer, M.A.1    Stott, A.K.2    Milne, K.A.3
  • 16
    • 0036719443 scopus 로고    scopus 로고
    • Health effects assessment for environmental perchlorate contamination: The dose response for inhibition of thyroid radioiodine uptake in humans
    • Greer MA, Goodman G, Pleus RC, Greer SE. 2002. Health effects assessment for environmental perchlorate contamination: The dose response for inhibition of thyroid radioiodine uptake in humans. Environ Health Pespect 9: 927-937.
    • (2002) Environ Health Pespect , vol.9 , pp. 927-937
    • Greer, M.A.1    Goodman, G.2    Pleus, R.C.3    Greer, S.E.4
  • 20
    • 0031010758 scopus 로고    scopus 로고
    • Regulation by thyroid-stimulating hormone of sodium/iodide symporter gene expression and protein levels in FRTL-5 cells
    • Kogai T, Endo T, Saito T, Miyazaki A, Kawaguchi A, Onaya T. 1997. Regulation by thyroid-stimulating hormone of sodium/iodide symporter gene expression and protein levels in FRTL-5 cells. Endocrinology 138: 2227-2232.
    • (1997) Endocrinology , vol.138 , pp. 2227-2232
    • Kogai, T.1    Endo, T.2    Saito, T.3    Miyazaki, A.4    Kawaguchi, A.5    Onaya, T.6
  • 22
    • 34447096645 scopus 로고    scopus 로고
    • Occurrence of perchlorate in drinking water sources of metropolitan area in Japan
    • Kosaka K, Asami M, Matsuoka Y, Kamoshita M, Kunikane S. 2007. Occurrence of perchlorate in drinking water sources of metropolitan area in Japan. Water Res 41: 3474-3482.
    • (2007) Water Res , vol.41 , pp. 3474-3482
    • Kosaka, K.1    Asami, M.2    Matsuoka, Y.3    Kamoshita, M.4    Kunikane, S.5
  • 23
    • 2342648122 scopus 로고    scopus 로고
    • Interspecies differences in susceptibility to perturbation of thyroid homeostasis: A case study with perchlorate
    • Lewandowski TA, Seeley MR, Beck BD. 2004. Interspecies differences in susceptibility to perturbation of thyroid homeostasis: A case study with perchlorate. Regul Toxicol Pharmacol 39: 348-362.
    • (2004) Regul Toxicol Pharmacol , vol.39 , pp. 348-362
    • Lewandowski, T.A.1    Seeley, M.R.2    Beck, B.D.3
  • 24
    • 34249661768 scopus 로고    scopus 로고
    • Iodine deficiency activates antioxidant genes and causes DNA damage in the thyroid gland of rats and mice
    • 1773
    • Maier J, van Steeg H, van Oostrom C, Paschke R, Weiss RE, Krohn K. 2007. Iodine deficiency activates antioxidant genes and causes DNA damage in the thyroid gland of rats and mice. Biochim Biophys Acta 1773: 990-999.
    • (2007) Biochim Biophys Acta , pp. 990-999
    • Maier, J.1    van Steeg, H.2    van Oostrom, C.3    Paschke, R.4    Weiss, R.E.5    Krohn, K.6
  • 25
    • 0018743066 scopus 로고
    • 4) and potassium iodide (KI) on the serum concentrations of thyrotrophin (TSH) and thyroid hormones in the rat
    • 4) and potassium iodide (KI) on the serum concentrations of thyrotrophin (TSH) and thyroid hormones in the rat. Acta Endocrinol 91: 271-281.
    • (1979) Acta Endocrinol , vol.91 , pp. 271-281
    • Männistö, P.T.1    Ranta, T.2    Leppäluoto, J.3
  • 26
    • 66349101879 scopus 로고    scopus 로고
    • Competitive inhibition of thyroidal uptake of dietary iodide by perchlorate does not describe perturbations in rat serum total T4 and TSH
    • McLanahan ED, Andersen ME, Campbell JL, Fisher JW. 2009. Competitive inhibition of thyroidal uptake of dietary iodide by perchlorate does not describe perturbations in rat serum total T4 and TSH. Environ Health Perspect 117: 731-738.
    • (2009) Environ Health Perspect , vol.117 , pp. 731-738
    • McLanahan, E.D.1    Andersen, M.E.2    Campbell, J.L.3    Fisher, J.W.4
  • 30
    • 77952876664 scopus 로고    scopus 로고
    • Genetics and phenomics of hypothyroidism and goiter due to TPO mutations
    • Ris-Stalpers C, Bikker H. 2010. Genetics and phenomics of hypothyroidism and goiter due to TPO mutations. Mol Cell Endocrinol 322: 38-43.
    • (2010) Mol Cell Endocrinol , vol.322 , pp. 38-43
    • Ris-Stalpers, C.1    Bikker, H.2
  • 33
    • 0023664176 scopus 로고
    • Thyroglobulin gene expression is regulated by insulin and insulin-like growth factor I, as well as thyrotropin, in FRTL-5 thyroid cells
    • Santisteban P, Kohn LD, Di Lauro R. 1987. Thyroglobulin gene expression is regulated by insulin and insulin-like growth factor I, as well as thyrotropin, in FRTL-5 thyroid cells. J Biol Chem 262: 4048-4052.
    • (1987) J Biol Chem , vol.262 , pp. 4048-4052
    • Santisteban, P.1    Kohn, L.D.2    Di Lauro, R.3
  • 34
    • 0037373327 scopus 로고    scopus 로고
    • The porcine sodium/iodide symporter gene exhibits an uncommon expression pattern related to the use of alternative splice sites not present in the human or murine species
    • Selmi-Ruby S, Watrin C, Trouttet-Masson S, Bernier-Valentin F, Flachon V, Munari-Silem Y, Rousset B. 2003. The porcine sodium/iodide symporter gene exhibits an uncommon expression pattern related to the use of alternative splice sites not present in the human or murine species. Endocrinology 144: 1074-1085.
    • (2003) Endocrinology , vol.144 , pp. 1074-1085
    • Selmi-Ruby, S.1    Watrin, C.2    Trouttet-Masson, S.3    Bernier-Valentin, F.4    Flachon, V.5    Munari-Silem, Y.6    Rousset, B.7
  • 35
    • 34547945777 scopus 로고    scopus 로고
    • Perchlorate in sewage sludge, rice, bottled water and milk collected from different areas in China
    • Shi Y, Zhang P, Wang Y, Shi J, Cai Y, Mou S, Jiang G. 2007. Perchlorate in sewage sludge, rice, bottled water and milk collected from different areas in China. Environ Int 33: 955-962.
    • (2007) Environ Int , vol.33 , pp. 955-962
    • Shi, Y.1    Zhang, P.2    Wang, Y.3    Shi, J.4    Cai, Y.5    Mou, S.6    Jiang, G.7
  • 36
    • 33749992853 scopus 로고    scopus 로고
    • Evaluation of ammonium perchlorate in the endocrine disruptor screening and testing program's male pubertal protocol: Ability to detect effects on thyroid endpoints
    • Stoker TE, Ferrell JM, Laws SC, Cooper RL, Buckalew A. 2006. Evaluation of ammonium perchlorate in the endocrine disruptor screening and testing program's male pubertal protocol: Ability to detect effects on thyroid endpoints. Toxicology 228: 58-65.
    • (2006) Toxicology , vol.228 , pp. 58-65
    • Stoker, T.E.1    Ferrell, J.M.2    Laws, S.C.3    Cooper, R.L.4    Buckalew, A.5
  • 37
    • 84863592026 scopus 로고    scopus 로고
    • Chlorate survey and development trend analysis
    • Article in Chinese).
    • Sun YZ, Cao HW, Ge YL. 2007. Chlorate survey and development trend analysis. Inorganic Chem Ind 39: 12-15 (Article in Chinese).
    • (2007) Inorganic Chem Ind , vol.39 , pp. 12-15
    • Sun, Y.Z.1    Cao, H.W.2    Ge, Y.L.3
  • 40
    • 77952876312 scopus 로고    scopus 로고
    • Genetics and phenomics of hypothyroidism and goiter due to thyroglobulin mutations
    • Targovnik HM, Esperante SA, Rivolta CM. 2010. Genetics and phenomics of hypothyroidism and goiter due to thyroglobulin mutations. Mol Cell Endocrinol 322: 44-55.
    • (2010) Mol Cell Endocrinol , vol.322 , pp. 44-55
    • Targovnik, H.M.1    Esperante, S.A.2    Rivolta, C.M.3
  • 41
    • 26944478884 scopus 로고    scopus 로고
    • Long-term environmental exposure to perchlorate through drinking water and thyroid function during pregnancy and the neonatal period
    • Téllez RT, Chacón PM, Abarca CR, Blount BC, Van Landingham CB, Crump KS, Gibbs JP. 2005. Long-term environmental exposure to perchlorate through drinking water and thyroid function during pregnancy and the neonatal period. Thyroid 15: 963-975.
    • (2005) Thyroid , vol.15 , pp. 963-975
    • Téllez, R.T.1    Chacón, P.M.2    Abarca, C.R.3    Blount, B.C.4    Van Landingham, C.B.5    Crump, K.S.6    Gibbs, J.P.7
  • 42
    • 33745101085 scopus 로고    scopus 로고
    • Development of a health-protective drinking water level for perchlorate
    • Ting D, Howd RA, Fan AM, Alexeeff GV. 2006. Development of a health-protective drinking water level for perchlorate. Environ Health Perspect 114: 881-886.
    • (2006) Environ Health Perspect , vol.114 , pp. 881-886
    • Ting, D.1    Howd, R.A.2    Fan, A.M.3    Alexeeff, G.V.4
  • 44
    • 0030921147 scopus 로고    scopus 로고
    • Moderate doses of iodide in vivo inhibit cell proliferation and the expression of thyroidperoxidase and Na/I symporter mRNA in dog thyroid
    • Uyttersprot N, Pelgrims N, Carrasco N, Gerry C, Maenhaut C, Dumont JE, Miot F. 1997. Moderate doses of iodide in vivo inhibit cell proliferation and the expression of thyroidperoxidase and Na/I symporter mRNA in dog thyroid. Mol Cell Endocrinol 131: 195-203.
    • (1997) Mol Cell Endocrinol , vol.131 , pp. 195-203
    • Uyttersprot, N.1    Pelgrims, N.2    Carrasco, N.3    Gerry, C.4    Maenhaut, C.5    Dumont, J.E.6    Miot, F.7
  • 47
    • 0026743033 scopus 로고
    • The thyrotropin receptor and the regulation of thyrocyte function and growth
    • Vassart G, Dumont JE. 1992. The thyrotropin receptor and the regulation of thyrocyte function and growth. Endocr Rev 13: 596-611.
    • (1992) Endocr Rev , vol.13 , pp. 596-611
    • Vassart, G.1    Dumont, J.E.2
  • 48
    • 0031894033 scopus 로고    scopus 로고
    • Perchlorate and the thyroid gland
    • Wolff J. 1998. Perchlorate and the thyroid gland. Pharmacol Rev 50: 89-105.
    • (1998) Pharmacol Rev , vol.50 , pp. 89-105
    • Wolff, J.1
  • 49
    • 0000815028 scopus 로고
    • Plasma inorganic iodide as a homeostatic regulator of thyroid function
    • Wolff J, Chaikoff IL. 1948. Plasma inorganic iodide as a homeostatic regulator of thyroid function. J Biol Chem 174: 555-564.
    • (1948) J Biol Chem , vol.174 , pp. 555-564
    • Wolff, J.1    Chaikoff, I.L.2
  • 50
    • 0038662787 scopus 로고    scopus 로고
    • Genes regulated by thyrotropin and iodide in cultured human thyroid follicles: Analysis by cDNA microarray
    • Yamazaki K, Yamada E, Kanaji Y, Yanagisawa T, Kato Y, Takano K, Obara T, Sato K. 2003. Genes regulated by thyrotropin and iodide in cultured human thyroid follicles: Analysis by cDNA microarray. Thyroid 13: 149-158.
    • (2003) Thyroid , vol.13 , pp. 149-158
    • Yamazaki, K.1    Yamada, E.2    Kanaji, Y.3    Yanagisawa, T.4    Kato, Y.5    Takano, K.6    Obara, T.7    Sato, K.8


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