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Volumn 35, Issue 7, 2012, Pages 1069-1075

Sertindole, a Potent Antagonist at Dopamine D2 Receptors, Induces Autophagy by Increasing Reactive Oxygen Species in SH-SY5Y Neuroblastoma Cells

Author keywords

ATG5; Autophagy; Reactive oxygen species; Sertindole; SH SY5Y cell

Indexed keywords

AUTOPHAGY PROTEIN 5; REACTIVE OXYGEN METABOLITE; SERTINDOLE;

EID: 84863556708     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b12-00009     Document Type: Article
Times cited : (36)

References (41)
  • 1
    • 35448981935 scopus 로고    scopus 로고
    • Autophagy: From phenomenology to molecular understanding in less than a decade
    • Klionsky DJ. Autophagy: from phenomenology to molecular understanding in less than a decade. Nat. Rev. Mol. Cell Biol., 8, 931-937 (2007).
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 931-937
    • Klionsky, D.J.1
  • 2
    • 81055144784 scopus 로고    scopus 로고
    • Autophagy: Renovation of cells and tissues
    • Mizushima N, Komatsu M. Autophagy: renovation of cells and tissues. Cell, 147, 728-741 (2011).
    • (2011) Cell , vol.147 , pp. 728-741
    • Mizushima, N.1    Komatsu, M.2
  • 3
    • 82755161734 scopus 로고    scopus 로고
    • Autophagy and disease: Always two sides to a problem
    • Sridhar S, Botbol Y, Macian F, Cuervo AM. Autophagy and disease: always two sides to a problem. J. Pathol., 226, 255-273 (2012).
    • (2012) J. Pathol. , vol.226 , pp. 255-273
    • Sridhar, S.1    Botbol, Y.2    Macian, F.3    Cuervo, A.M.4
  • 4
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature, 451, 1069-1075 (2008).
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 5
    • 79960635284 scopus 로고    scopus 로고
    • Fighting neurodegeneration with rapamycin: Mechanistic insights
    • Bové J, Martínez-Vicente M, Vila M. Fighting neurodegeneration with rapamycin: mechanistic insights. Nat. Rev. Neurosci., 12, 437-452 (2011).
    • (2011) Nat. Rev. Neurosci. , vol.12 , pp. 437-452
    • Bové, J.1    Martínez-Vicente, M.2    Vila, M.3
  • 10
    • 78650448754 scopus 로고    scopus 로고
    • Chemical modulators of autophagy as biological probes and potential therapeutics
    • Fleming A, Noda T, Yoshimori T, Rubinsztein DC. Chemical modulators of autophagy as biological probes and potential therapeutics. Nat. Chem. Biol., 7, 9-17 (2011).
    • (2011) Nat. Chem. Biol. , vol.7 , pp. 9-17
    • Fleming, A.1    Noda, T.2    Yoshimori, T.3    Rubinsztein, D.C.4
  • 17
    • 25144466069 scopus 로고    scopus 로고
    • The choice of antipsychotic drugs for schizophrenia
    • Freedman R. The choice of antipsychotic drugs for schizophrenia. N. Engl. J. Med., 353, 1286-1288 (2005).
    • (2005) N. Engl. J. Med. , vol.353 , pp. 1286-1288
    • Freedman, R.1
  • 18
    • 45949095610 scopus 로고    scopus 로고
    • Sertindole: Pharmacological and clinical profile and role in the treatment of schizophrenia
    • Spina E, Zoccali R. Sertindole: pharmacological and clinical profile and role in the treatment of schizophrenia. Expert Opin. Drug Metab. Toxicol., 4, 629-638 (2008).
    • (2008) Expert Opin. Drug Metab. Toxicol. , vol.4 , pp. 629-638
    • Spina, E.1    Zoccali, R.2
  • 19
    • 77950352932 scopus 로고    scopus 로고
    • The European post-marketing observational sertindole study: An investigation of the safety of antipsychotic drug treatment
    • Kasper S, Möller HJ, Hale A. The European post-marketing observational sertindole study: an investigation of the safety of antipsychotic drug treatment. Eur. Arch. Psychiatry Clin. Neurosci., 260, 59-68 (2010).
    • (2010) Eur. Arch. Psychiatry Clin. Neurosci. , vol.260 , pp. 59-68
    • Kasper, S.1    Möller, H.J.2    Hale, A.3
  • 20
    • 0032410714 scopus 로고    scopus 로고
    • The antipsychotic agent sertindole is a high affinity antagonist of the human cardiac potassium channel HERG
    • Rampe D, Murawsky MK, Grau J, Lewis EW. The antipsychotic agent sertindole is a high affinity antagonist of the human cardiac potassium channel HERG. J. Pharmacol. Exp. Ther., 286, 788-793 (1998).
    • (1998) J. Pharmacol. Exp. Ther. , vol.286 , pp. 788-793
    • Rampe, D.1    Murawsky, M.K.2    Grau, J.3    Lewis, E.W.4
  • 21
    • 0034815059 scopus 로고    scopus 로고
    • The antipsychotic drugs sertindole and pimozide block erg3, a human brain K(+) channel
    • Kang J, Chen XL, Rampe D. The antipsychotic drugs sertindole and pimozide block erg3, a human brain K(+) channel. Biochem. Biophys. Res. Commun., 286, 499-504 (2001).
    • (2001) Biochem. Biophys. Res. Commun. , vol.286 , pp. 499-504
    • Kang, J.1    Chen, X.L.2    Rampe, D.3
  • 22
    • 33646204392 scopus 로고    scopus 로고
    • Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size
    • Hosokawa N, Hara Y, Mizushima N. Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size. FEBS Lett., 580, 2623-2629 (2006).
    • (2006) FEBS Lett. , vol.580 , pp. 2623-2629
    • Hosokawa, N.1    Hara, Y.2    Mizushima, N.3
  • 24
    • 80052876115 scopus 로고    scopus 로고
    • Niclosamide induces mitochondria fragmentation and promotes both apoptotic and autophagic cell death
    • Park SJ, Shin JH, Kang H, Hwang JJ, Cho DH. Niclosamide induces mitochondria fragmentation and promotes both apoptotic and autophagic cell death. BMB Rep, 44, 517-522 (2011).
    • (2011) BMB Rep. , vol.44 , pp. 517-522
    • Park, S.J.1    Shin, J.H.2    Kang, H.3    Hwang, J.J.4    Cho, D.H.5
  • 26
    • 79951630345 scopus 로고    scopus 로고
    • Gene expression signature is shared by patients with Alzheimer's disease and schizophrenia at the superior temporal gyrus
    • Horesh Y, Katsel P, Haroutunian V, Domany E. Gene expression signature is shared by patients with Alzheimer's disease and schizophrenia at the superior temporal gyrus. Eur. J. Neurol., 18, 410-424 (2011).
    • (2011) Eur. J. Neurol. , vol.18 , pp. 410-424
    • Horesh, Y.1    Katsel, P.2    Haroutunian, V.3    Domany, E.4
  • 27
    • 58149096404 scopus 로고    scopus 로고
    • ApoL1, a BH3-only lipid-binding protein, induces autophagic cell death
    • Zhaorigetu S, Wan G, Kaini R, Jiang Z, Hu CA. ApoL1, a BH3-only lipid-binding protein, induces autophagic cell death. Autophagy, 4, 1079-1082 (2008).
    • (2008) Autophagy , vol.4 , pp. 1079-1082
    • Zhaorigetu, S.1    Wan, G.2    Kaini, R.3    Jiang, Z.4    Hu, C.A.5
  • 28
    • 77957666080 scopus 로고    scopus 로고
    • Glutaminolysis yields a metabolic by-product that stimulates autophagy
    • Eng CH, Abraham RT. Glutaminolysis yields a metabolic by-product that stimulates autophagy. Autophagy, 6, 968-970 (2010).
    • (2010) Autophagy , vol.6 , pp. 968-970
    • Eng, C.H.1    Abraham, R.T.2
  • 30
    • 0032479846 scopus 로고    scopus 로고
    • Intrastriatal injection of dopamine results in DNA damage and apoptosis in rats
    • Hattori A, Luo Y, Umegaki H, Munoz J, Roth GS. Intrastriatal injection of dopamine results in DNA damage and apoptosis in rats. Neuroreport, 9, 2569-2572 (1998).
    • (1998) Neuroreport , vol.9 , pp. 2569-2572
    • Hattori, A.1    Luo, Y.2    Umegaki, H.3    Munoz, J.4    Roth, G.S.5
  • 32
    • 33644499124 scopus 로고    scopus 로고
    • Dopamine in neurotoxicity and neuroprotection: What do D2 receptors have to do with it?
    • Bozzi Y, Borrelli E. Dopamine in neurotoxicity and neuroprotection: what do D2 receptors have to do with it? Trends Neurosci., 29, 167-174 (2006).
    • (2006) Trends Neurosci. , vol.29 , pp. 167-174
    • Bozzi, Y.1    Borrelli, E.2
  • 33
    • 79954629446 scopus 로고    scopus 로고
    • Dopamine D2-receptor knockout mice are protected against dopaminergic neurotoxicity induced by methamphetamine or MDMA
    • Granado N, Ares-Santos S, Oliva I, O'Shea E, Martin ED, Colado MI, Moratalla R. Dopamine D2-receptor knockout mice are protected against dopaminergic neurotoxicity induced by methamphetamine or MDMA. Neurobiol. Dis., 42, 391-403 (2011).
    • (2011) Neurobiol. Dis. , vol.42 , pp. 391-403
    • Granado, N.1    Ares-Santos, S.2    Oliva, I.3    O'Shea, E.4    Martin, E.D.5    Colado, M.I.6    Moratalla, R.7
  • 34
    • 0037955959 scopus 로고    scopus 로고
    • Neuroprotective mechanisms of antiparkinsonian dopamine D2-receptor subfamily agonists
    • Kitamura Y, Taniguchi T, Shimohama S, Akaike A, Nomura Y. Neuroprotective mechanisms of antiparkinsonian dopamine D2-receptor subfamily agonists. Neurochem. Res., 28, 1035-1040 (2003).
    • (2003) Neurochem. Res. , vol.28 , pp. 1035-1040
    • Kitamura, Y.1    Taniguchi, T.2    Shimohama, S.3    Akaike, A.4    Nomura, Y.5
  • 36
    • 0028100663 scopus 로고
    • Dopamine-induced protection of striatal neurons against kainate receptor-mediated glutamate cytotoxicity in vitro
    • Amano T, Ujihara H, Matsubayashi H, Sasa M, Yokota T, Tamura Y, Akaike A. Dopamine-induced protection of striatal neurons against kainate receptor-mediated glutamate cytotoxicity in vitro. Brain Res., 655, 61-69 (1994).
    • (1994) Brain Res. , vol.655 , pp. 61-69
    • Amano, T.1    Ujihara, H.2    Matsubayashi, H.3    Sasa, M.4    Yokota, T.5    Tamura, Y.6    Akaike, A.7
  • 37
    • 0031214452 scopus 로고    scopus 로고
    • Attenuation of oxidative neuronal necrosis by a dopamine D1 agonist in mouse cortical cell cultures
    • Noh JS, Gwag BJ. Attenuation of oxidative neuronal necrosis by a dopamine D1 agonist in mouse cortical cell cultures. Exp. Neurol., 146, 604-608 (1997).
    • (1997) Exp. Neurol. , vol.146 , pp. 604-608
    • Noh, J.S.1    Gwag, B.J.2
  • 38
    • 0028068121 scopus 로고
    • Bromocriptine protects mice against 6-hydroxydopamine and scavenges hydroxyl free radicals in vitro
    • Ogawa N, Tanaka K, Asanuma M, Kawai M, Masumizu T, Kohno M, Mori A. Bromocriptine protects mice against 6-hydroxydopamine and scavenges hydroxyl free radicals in vitro. Brain Res., 657, 207-213 (1994).
    • (1994) Brain Res. , vol.657 , pp. 207-213
    • Ogawa, N.1    Tanaka, K.2    Asanuma, M.3    Kawai, M.4    Masumizu, T.5    Kohno, M.6    Mori, A.7
  • 40
    • 78650890352 scopus 로고    scopus 로고
    • Regulation of autophagy by ROS: Physiology and pathology
    • Scherz-Shouval R, Elazar Z. Regulation of autophagy by ROS: physiology and pathology. Trends Biochem. Sci., 36, 30-38 (2011).
    • (2011) Trends Biochem. Sci. , vol.36 , pp. 30-38
    • Scherz-Shouval, R.1    Elazar, Z.2
  • 41
    • 79956118584 scopus 로고    scopus 로고
    • Autophagy signaling through reactive oxygen species
    • Huang J, Lam GY, Brumell JH. Autophagy signaling through reactive oxygen species. Antioxid. Redox Signal., 14, 2215-2231 (2011).
    • (2011) Antioxid. Redox Signal. , vol.14 , pp. 2215-2231
    • Huang, J.1    Lam, G.Y.2    Brumell, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.