The Use of Low-Calorie Sweeteners by Children: Implications for Weight Management

Journal of Nutrition

Volumn 142, Issue 6, 2012, Pages

  Foreyt, John ^a   Kleinman, Ronald ^b   Brown, Rebecca J ^c   Lindstrom, Rachel ^d  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d America on the Move Foundation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SWEETENING AGENT;

ADOLESCENT HEALTH; ARTICLE; CHILD HEALTH; CORRELATION ANALYSIS; DIET; FOOD INTAKE; GENETIC ANALYSIS; HUMAN; LIFESTYLE; LOW CALORY DIET; OBESITY; WEIGHT CONTROL; WEIGHT GAIN; WEIGHT REDUCTION;

ADOLESCENT; ADOLESCENT NUTRITIONAL PHYSIOLOGICAL PHENOMENA; CHILD; CHILD NUTRITIONAL PHYSIOLOGICAL PHENOMENA; CHILD, PRESCHOOL; ENERGY INTAKE; HUMANS; INFANT; OBESITY; SWEETENING AGENTS; UNITED STATES; WEIGHT LOSS;

EID: 84863541940     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.111.149609     Document Type: Article

References (63)

1. Ogden CL, Carroll MD, Curtin LR, Lamb MM, Flegal KM. Prevalence of high body mass index in US children and adolescents, 2007-2008. JAMA. 2010;303:242-9.
2. Popkin BM. Recent dynamics suggest selected countries catching up to US obesity. Am J Clin Nutr. 2010;91 Suppl:S284-8.
3. Stewart ST, Cutler DM, Rosen AB. Forecasting the effects of obesity and smoking on US life expectancy. N Engl J Med. 2009;361:2252-60.
4. SEARCH for Diabetes in Youth Study Group, Liese AD, D'Agostino RB Jr, Hamman RF, Kilgo PD, Lawrence JM, Liu LL, Loots B, Linder B, Marcovina S, et al. The burden of diabetes mellitus among US youth: prevalence estimates from the SEARCH for Diabetes in Youth Study Group. Pediatrics. 2006;118:1510-8.
5. Pacifico L, Anania C, Martino F, Cantisani V, Pascone R, Marcantonio A, Chiesa C. Functional and morphological vascular change in pediatric nonalcoholic fatty liver disease. Hepatology. 2010;52:1643-51.
6. Freedman DS, Mei Z, Srinivasan SR, Berenson GS, Dietz WH. Cardiovascular risk factors and excess adiposity among overweight children and adolescents: the Bogalusa Heart Study. J Pediatr. 2007;150: 12-7.
7. CDC. Prevalence of abnormal lipid levels among youths: United States, 1999-2006. MMWR Morb Mortal Wkly Rep. 2010;59:29-33.
8. Wang G, Dietz WH. Economic burden of obesity in youths aged 6 to 17 years: 1979-1999. Pediatrics. 2002;109:E81.
9. Moseley KL, Freed GL, Goold SD. Which sources of child health advice do parents follow? Clin Pediatr (Phila). 2011;50:50-6.
10. CDC. CDC grand rounds: childhood obesity in the United States. MMWR Morb Mortal Wkly Rep. 2011;60:42-6.
11. WHO Multicentre Growth Reference Study Group. WHO Child Growth Standards based on length/height, weight and age. Acta Paediatr Suppl. 2006;450:76-85.
12. Grummer-Strawn LM, Reinold C, Krebs NF, CDC. Use ofWorld Health Organization and CDC growth charts for children aged 0-59 months in the United States. MMWR Recomm Rep. 2010;59:1-15.
13. Ben-Joseph EP, Dowshen SA, Izenberg N. Do parents understand growth charts? A national, internet-based survey. Pediatrics. 2009;124:1100-9.
14. Laraway KA, Birch LL, Shaffer ML, Paul IM. Parent perception of healthy infant and toddler growth. Clin Pediatr (Phila). 2010;49:343-9.
15. Taveras EM, Rifas-Shiman SL, Sherry B, Oken E, Haines J, Kleinman K, Rich-Edwards JW, Gillman MW. Crossing growth percentiles in infancy and risk of obesity in childhood. Arch Pediatr Adolesc Med. 2011; 165:993-8.
16. Jimenez-Cruz A, Bacardi-Gascon M, Castillo-Ruiz O, Mandujano-Trujillo Z, Pichardo-Osuna. Low income, Mexican mothers' perception of their infants' weight status and beliefs about their foods and physical activity. Child Psychiatry Hum Dev. 2010;41:490-500.
17. Manios Y, Moschonis G, Grammatikaki E, Anastasiadou A, Liarigkovinos T. Determinants of childhood obesity and association with maternal perception of their children's weight status: The "GENESIS" Study. J Am Diet Assoc. 2010;110:1527-31.
18. Towns N, D'Auria J. Parental perceptions of their child's overweight: an integrative review of the literature. J Pediatr Nurs. 2009;24:115-30.
19. American Academy of Pediatrics. Prevention and treatment of childhood overweight and obesity; 2010 [cited 2011 Dec 8]. Available from: http://www.aap.org/obesity/letsmove.
20. Sylvetsky A, Rother KI, Brown R. Artificial sweetener use among children: epidemiology, recommendations, metabolic outcomes, and future directions. Pediatr Clin North Am. 2011;58:1467-80.
21. Nelson G, Hoon MA, Chandrashekar J, Zhang Y, Ryba NJ, Zuker CS. Mammalian sweet taste receptors. Cell. 2001;106:381-90.
22. Benton D. Can artificial sweeteners help control body weight and prevent obesity? Nutr Res Rev. 2005;18:63-76.
23. Williams CL, Strobino BA, Brotanek J. Weight control among obese adolescents: a pilot study. Int J Food Sci Nutr. 2007;58:217-30.
24. Bellisle F, Altenburg de Assis MA, Fieux B, Preziosi P, Galan P, Guy-Grand B, Hercberg S. Use of 'light' foods and drinks in French adults: biological, anthropometric and nutritional correlates. J Hum Nutr Diet. 2001;14:191-206.
25. Husøy T, Mangschou B, Fotland TO, Kolset SO, Jakobsen HN, Tommerberg I, Bergsten C, Alexander J, Frost Andersen L. Reducing added sugar intake in Norway by replacing sugar sweetened beverages with beverages containing intense sweeteners: a risk benefit assessment. Food Chem Toxicol. 2008;46:3099-105.
26. Guthrie JF, Morton JF. Food sources of added sweeteners in the diets of Americans. J Am Diet Assoc. 2000;100:43-51, quiz 49-50.
27. Bellisle F, Drewnowski A. Intense sweeteners, energy intake and the control of body weight. Eur J Clin Nutr. 2007;61:691-700.
28. Morris DH, Cuneo P, Stuart MJ, Mance MJ, Bell KJ, Puleo E, Ahmadi S, Ward A, Rippe JM. High-intensity sweetener, energy and nutrient intakes of overweight women and men participating in a weight-loss program. Nutr Res. 1993;13:123-32.
29. Brown RJ, de Banate MA, Rother KI. Artificial sweeteners: a systematic review of metabolic effects in youth. Int J Pediatr Obes. 2010;5: 305-12.
30. Mattes RD, Popkin BM. Nonnutritive sweetener consumption in humans: effects on appetite and food intake and their putative mechanisms. Am J Clin Nutr. 2009;89:1-14.
31. Forshee RA, StoreyML. Total beverage consumption and beverage choices among children and adolescents. Int J Food Sci Nutr. 2003;54:297-307.
32. Giammattei J, Blix G, Marshak HH,Wollitzer AO, Pettitt DJ. Television watching and soft drink consumption: associations with obesity in 11-to 13-year-old schoolchildren. Arch Pediatr Adolesc Med. 2003;157: 882-6.
33. O'Connor TM, Yang SJ, Nicklas TA. Beverage intake among preschool children and its effect on weight status. Pediatrics. 2006;118:e1010-8.
34. Berkey CS, Rockett HR, Field AE, Gillman MW, Colditz GA. Sugaradded beverages and adolescent weight change. Obes Res. 2004;12: 778-88.
35. Blum JW, Jacobsen DJ, Donnelly JE. Beverage consumption patterns in elementary school aged children across a two-year period. J Am Coll Nutr. 2005;24:93-8.
36. Striegel-Moore RH, Thompson D, Affenito SG, Franko DL, Obarzanek E, Barton BA, Schreiber GB, Daniels SR, Schmidt M, Crawford PB. Correlates of beverage intake in adolescent girls: the National Heart, Lung, and Blood Institute Growth and Health Study. J Pediatr. 2006; 148:183-7.
37. Johnson L, Mander AP, Jones LR, Emmett PM, Jebb SA. Is sugarsweetened beverage consumption associated with increased fatness in children? Nutrition. 2007;23:557-63.
38. Ludwig DS. Relation between consumption of sugar sweetened drinks and childhood obesity: a prospective, observational analysis. Lancet. 2001;357:505-8.
39. Kral TV, Stunkard AJ, Berkowitz RI, Stallings VA, Moore RH, Faith MS. Beverage consumption patterns of children born at different risk of obesity. Obesity (Silver Spring). 2008;16:1802-8.
40. Bellissimo N, Thomas SG, Goode RC, Anderson GH. Effect of shortduration physical activity and ventilation threshold on subjective appetite and short-term energy intake in boys. Appetite. 2007;49: 644-51.
41. Bellissimo N, Pencharz PB, Thomas SG, Anderson GH. Effect of television viewing atmealtime on food intake after a glucose preload in boys. Pediatr Res. 2007;61:745-9.
42. Birch LL, Deysher M. Caloric compensation and sensory specific satiety: evidence for self regulation of food intake by young children. Appetite. 1986;7:323-31.
43. Birch LL, McPhee L, Sullivan S. Children's food intake following drinks sweetened with sucrose or aspartame: time course effects. Physiol Behav. 1989;45:387-95.
44. Anderson GH, Saravis S, Schacher R, Zlotkin S, Leiter LA. Aspartame: effect on lunch-time food intake, appetite and hedonic response in children. Appetite. 1989;13:93-103.
45. Birch LL, Deysher M. Conditioned and unconditioned caloric compensation: evidence for self-regulation of food intake in young children. Learn Motiv. 1985;16:341-55.
46. Johnson SL, Taylor-Holloway LA. Non-Hispanic white and Hispanic elementary school children's self-regulation of energy intake. Am J Clin Nutr. 2006;83:1276-82.
47. Knopp RH, Brandt K, Arky RA. Effects of aspartame in young persons during weight reduction. J Toxicol Environ Health. 1976;2:417-28.
48. Ebbeling CB, Feldman HA, Osganian SK, Chomitz VR, Ellenbogen SJ, Ludwig DS. Effects of decreasing sugar-sweetened beverage consumption on body weight in adolescents: a randomized, controlled pilot study. Pediatrics. 2006;117:673-80.
49. Rodearmel SJ, Wyatt HR, Stroebele N, Smith SM, Ogden LG, Hill JO. Small changes in dietary sugar and physical activity as an approach to preventing excessive weight gain: the America On the Move family study. Pediatrics. 2007;120:e869-79.
50. Hill JO, Wyatt HR, Reed GW, Peters JC. Obesity and the environment: where do we go from here? Science. 2003;299:853-5.
51. Rolls BJ, Morris EL, Roe LS. Portion size of food affects energy intake in normal-weight and overweight men and women. Am J Clin Nutr. 2002;76:1207-13.
52. Stroebele N, de Castro JM, Stuht J, Catenacci V, Wyatt HR, Hill JO. A small-changes approach reduces energy intake in free-living humans. J Am Coll Nutr. 2009;28:63-8.
53. Rodearmel SJ, Wyatt HR, Barry MJ, Dong F, Pan D, Israel RG, Cho SS, McBurney MI, Hill JO. A family-based approach to preventing excessive weight gain. Obesity (Silver Spring). 2006;14:1392-401.
54. Johnson RJ, Segal MS, Sautin Y, Nakagawa T, Feig DI, Kang DH, Gersch MS, Benner S, Sanchex-Lozada LG. Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease. Am J Clin Nutr. 2007;86:899-906.
55. Wang, YC, Bleich SN, Gortmaker SL. Increasing caloric contribution from sugar-sweetened beverages and 100% fruit juices among US children and adolescents, 1988-2004. Pediatrics. 2008;121:e1604-14.
56. Swithers SE, Martin AA, Davidson TL. High-intensity sweeteners and energy balance. Physiol Behav. 2010;100:55-62.
57. Landrigan PJ, Trasande L, Thorpe LE, Gwynn C, Lioy PJ, D'Alton ME, Lipkind HS, Swanson J, Wadhwa PD, Clark EB, et al. The National Children's Study: a 21-year prospective study of 100,000 American children. Pediatrics. 2006;118:2173-86.
58. Dyer J, Salmon KS, Zibrik L, Shirazi-Beechey SP. Expression of sweet taste receptors of the T1R family in the intestinal tract and enteroendocrine cells. Biochem Soc Trans. 2005;33:302-5.
59. Jang HJ, Kokrashvili Z, Theodorakis MJ, Carlson OD, Kim BJ, Zhou J, Kim HH, Xu X, Chan SL, Rauh VA, et al. Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. Proc Natl Acad Sci USA. 2007;104:15069-74.
60. Margolskee RF, Dyer J, Kokrashvili Z, Salmon KS, Ilegems E, Daly K, Maillet EL, Ninomiya Y, Mosinger B, Shirazi-Beechey SP. T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1. Proc Natl Acad Sci USA. 2007;104:15075-80.
61. Mace OJ, Affleck J, Patel N, Kellett GL. Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2. J Physiol. 2007;582:379-92.
62. Brown RJ, Walter M, Rother KI. Ingestion of diet soda before a glucose load augments glucagon-like peptide-1 secretion. Diabetes Care. 2009;32:2184-6.
63. Brown RJ. Metabolic effects of non-nutritive sweeteners; 2001 [cited 2011 Feb 22]. Available from: http://www.clinicaltrials.gov/ct2/show/NCT01200940.