메뉴 건너뛰기




Volumn 119, Issue 26, 2012, Pages 6268-6277

ICOS-LICOS interaction is critically involved in TGN1412-mediated T-cell activation

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTIBODY TGN 1412; CYTOKINE; FC RECEPTOR; IMMUNOGLOBULIN FC FRAGMENT; INDUCIBLE T CELL COSTIMULATOR; INDUCIBLE T CELL COSTIMULATOR LIGAND; UNCLASSIFIED DRUG;

EID: 84863522488     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-12-401083     Document Type: Article
Times cited : (21)

References (42)
  • 2
    • 0029565168 scopus 로고
    • Side-effects of a monoclonal antibody, muromonab CD3/orthoclone OKT3: Bibliographic review
    • Sgro C. Side-effects of a monoclonal antibody, muromonab CD3/orthoclone OKT3: bibliographic review. Toxicology. 1995;105(1):23-29.
    • (1995) Toxicology , vol.105 , Issue.1 , pp. 23-29
    • Sgro, C.1
  • 3
    • 65349104572 scopus 로고    scopus 로고
    • Mechanisms of costimulation
    • Sharpe AH. Mechanisms of costimulation. Immunol Rev. 2009;229(1):5-11.
    • (2009) Immunol Rev. , vol.229 , Issue.1 , pp. 5-11
    • Sharpe, A.H.1
  • 5
    • 0035292756 scopus 로고    scopus 로고
    • The expanding B7 superfamily: Increasing complexity in costimulatory signals regulating T cell function
    • DOI 10.1038/85251
    • Coyle AJ, Gutierrez-Ramos JC. The expanding B7 superfamily: increasing complexity in costimulatory signals regulating T cell function. Nat Immunol. 2001;2(3):203-209. (Pubitemid 33705995)
    • (2001) Nature Immunology , vol.2 , Issue.3 , pp. 203-209
    • Coyle, A.J.1    Gutierrez-Ramos, J.-C.2
  • 7
    • 77952348017 scopus 로고    scopus 로고
    • Regulation of CD4 T-cell activation and effector function by inducible costimulator (ICOS)
    • Simpson TR, Quezada SA, Allison JP. Regulation of CD4 T-cell activation and effector function by inducible costimulator (ICOS). Curr Opin Immunol. 2010;22(3):326-332.
    • (2010) Curr Opin Immunol. , vol.22 , Issue.3 , pp. 326-332
    • Simpson, T.R.1    Quezada, S.A.2    Allison, J.P.3
  • 8
    • 78049518331 scopus 로고    scopus 로고
    • The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells
    • Paulos CM, Carpenito C, Plesa G, et al. The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells. Sci Transl Med. 2010;2(55):55ra78.
    • (2010) Sci Transl Med. , vol.2 , Issue.55
    • Paulos, C.M.1    Carpenito, C.2    Plesa, G.3
  • 10
    • 71749108311 scopus 로고    scopus 로고
    • Improved in vitro methods to predict the in vivo toxicity in man of therapeutic monoclonal antibodies including TGN1412
    • Findlay L, Eastwood D, Stebbings R, et al. Improved in vitro methods to predict the in vivo toxicity in man of therapeutic monoclonal antibodies including TGN1412. J. Immunol Methods. 2010;352(1-2):1-12.
    • (2010) J. Immunol Methods. , vol.352 , Issue.1-2 , pp. 1-12
    • Findlay, L.1    Eastwood, D.2    Stebbings, R.3
  • 11
    • 37749032491 scopus 로고    scopus 로고
    • "Cytokine storm" in the phase I trial of monoclonal antibody TGN1412: Better understanding the causes to improve preclinical testing of immunotherapeutics
    • Stebbings R, Findlay L, Edwards C, et al. "Cytokine storm" in the phase I trial of monoclonal antibody TGN1412: better understanding the causes to improve preclinical testing of immunotherapeutics. J Immunol. 2007;179(5):3325-3331.
    • (2007) J Immunol. , vol.179 , Issue.5 , pp. 3325-3331
    • Stebbings, R.1    Findlay, L.2    Edwards, C.3
  • 12
    • 43049154225 scopus 로고    scopus 로고
    • Signaling signatures and functional properties of antihuman CD28 superagonistic antibodies
    • Waibler Z, Sender LY, Merten C, et al. Signaling signatures and functional properties of antihuman CD28 superagonistic antibodies. PLoS One. 2008;3(3):e1708.
    • (2008) PLoS One , vol.3 , Issue.3
    • Waibler, Z.1    Sender, L.Y.2    Merten, C.3
  • 13
    • 0026544070 scopus 로고
    • Characterization of IgG FcR-mediated proliferation of human T cells induced by mouse and human anti-CD3 monoclonal antibodies. Identification of a functional polymorphism to human IgG2 anti-CD3
    • Parren PW,Warmerdam PA, Boeije LC, Capel PJ, van de Winkel JG, Aarden LA. Characterization of IgG FcR-mediated proliferation of human T cells induced by mouse and human anti-CD3 monoclonal antibodies. Identification of a functional polymorphism to human IgG2 anti-CD3. J Immunol. 1992;148(3):695-701.
    • (1992) J Immunol. , vol.148 , Issue.3 , pp. 695-701
    • Parren, P.W.1    Warmerdam, P.A.2    Boeije, L.C.3    Capel, P.J.4    Van De Winkel, J.G.5    Aarden, L.A.6
  • 14
    • 0022618123 scopus 로고
    • 1 and IgG(2b) switch variants and direct evidence for accessory function of macrophage Fc receptors
    • Smith KG, Austyn JM, Hariri G, Beverley PC, Morris PJ. T-cell activation by anti-T3 antibodies: comparison of IgG1 and IgG2b switch variants and direct evidence for accessory function of macrophage Fc receptors. Eur J Immunol. 1986;16(5):478-486. (Pubitemid 16103043)
    • (1986) European Journal of Immunology , vol.16 , Issue.5 , pp. 478-486
    • Smith, K.G.C.1    Austyn, J.M.2    Hairiri, G.3
  • 15
    • 0020578878 scopus 로고
    • Polymorphism in mitogenic effect of IgG1 monoclonal antibodies against T3 antigen on human T cells
    • Tax WJ, Willems HW, Reekers PP, Capel PJ, Koene RA. Polymorphism in mitogenic effect of IgG1 monoclonal antibodies against T3 antigen on human T cells. Nature. 1983;304(5925):445-447. (Pubitemid 13077944)
    • (1983) Nature , vol.304 , Issue.5925 , pp. 445-447
    • Tax, W.J.M.1    Willems, H.W.2    Reekers, P.P.M.3
  • 16
    • 0025204280 scopus 로고
    • Anti-CD3 murine monoclonal isotype switch variants tested for toxicity and immunologic monitoring in four chimpanzees
    • Parleviet KJ, Jonker M, ten Berge RJ, et al. Anti-CD3 murine monoclonal isotype switch variants tested for toxicity and immunologic monitoring in four chimpanzees. Transplantation. 1990;50(5):889-892.
    • (1990) Transplantation , vol.50 , Issue.5 , pp. 889-892
    • Parleviet, K.J.1    Jonker, M.2    Ten Berge, R.J.3
  • 17
    • 0025991961 scopus 로고
    • OKT3E, an anti-CD3 antibody that does not elicit side effects or antiidiotype responses in chimpanzees
    • Rao PE, Olini G, Kille J, et al. OKT3E, an anti-CD3 antibody that does not elicit side effects or antiidiotype responses in chimpanzees. Transplantation. 1991;52(4):691-697.
    • (1991) Transplantation , vol.52 , Issue.4 , pp. 691-697
    • Rao, P.E.1    Olini, G.2    Kille, J.3
  • 19
    • 55549108671 scopus 로고    scopus 로고
    • Toward experimental assessment of receptor occupancy: TGN1412 revisited
    • Waibler Z, Sender LY, Kamp C, et al. Toward experimental assessment of receptor occupancy: TGN1412 revisited. J Allergy Clin Immunol. 2008;122(5):890-892.
    • (2008) J Allergy Clin Immunol. , vol.122 , Issue.5 , pp. 890-892
    • Waibler, Z.1    Sender, L.Y.2    Kamp, C.3
  • 20
    • 34247122497 scopus 로고    scopus 로고
    • The impact of glycosylation on the biological function and structure of human immunoglobulins
    • DOI 10.1146/annurev.immunol.25.022106.141702
    • Arnold JN, Wormald MR, Sim RB, Rudd PM, Dwek RA. The impact of glycosylation on the biological function and structure of human immunoglobulins. Annu Rev Immunol. 2007;25:21-50. (Pubitemid 46697901)
    • (2007) Annual Review of Immunology , vol.25 , pp. 21-50
    • Arnold, J.N.1    Wormald, M.R.2    Sim, R.B.3    Rudd, P.M.4    Dwek, R.A.5
  • 21
    • 37549036732 scopus 로고    scopus 로고
    • Fcgamma receptors as regulators of immune responses
    • Nimmerjahn F, Ravetch JV. Fcgamma receptors as regulators of immune responses. Nat Rev Immunol. 2008;8(1):34-47.
    • (2008) Nat Rev Immunol. , vol.8 , Issue.1 , pp. 34-47
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 22
    • 1142298744 scopus 로고    scopus 로고
    • Human antibody-Fc receptor interactions illuminated by crystal structures
    • Woof JM, Burton DR. Human antibody-Fc receptor interactions illuminated by crystal structures. Nat Rev Immunol. 2004;4(2):89-99. (Pubitemid 38209203)
    • (2004) Nature Reviews Immunology , vol.4 , Issue.2 , pp. 89-99
    • Woof, J.M.1    Burton, D.R.2
  • 23
    • 0027087331 scopus 로고
    • Costimulation of T lymphocytes: The role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy
    • DOI 10.1016/S0092-8674(05)80055-8
    • Schwartz RH. Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. Cell. 1992;71(7):1065-1068. (Pubitemid 23016541)
    • (1992) Cell , vol.71 , Issue.7 , pp. 1065-1068
    • Schwartz, R.H.1
  • 24
    • 33748428203 scopus 로고    scopus 로고
    • T-cell costimulation - Biology, therapeutic potential, and challenges
    • DOI 10.1056/NEJMp068087
    • Sharpe AH, Abbas AK. T-cell costimulation-biology, therapeutic potential, and challenges. N Engl J Med. 2006;355(10):973-975. (Pubitemid 44343539)
    • (2006) New England Journal of Medicine , vol.355 , Issue.10 , pp. 973-975
    • Sharpe, A.H.1    Abbas, A.K.2
  • 25
    • 77956304908 scopus 로고    scopus 로고
    • Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells
    • Eastwood D, Findlay L, Poole S, et al. Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells. Br J Pharmacol. 2010;161(3):512-526.
    • (2010) Br J Pharmacol. , vol.161 , Issue.3 , pp. 512-526
    • Eastwood, D.1    Findlay, L.2    Poole, S.3
  • 26
    • 84255160968 scopus 로고    scopus 로고
    • Preculture of PBMC at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412
    • Römer PS, Berr S, Avota E, et al. Preculture of PBMC at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412. Blood. 2011;118(26):6772-6782
    • (2011) Blood , vol.118 , Issue.26 , pp. 6772-6782
    • Römer, P.S.1    Berr, S.2    Avota, E.3
  • 27
    • 79956341877 scopus 로고    scopus 로고
    • Endothelial cells co-stimulate peripheral blood mononuclear cell responses to monoclonal antibody TGN1412 in culture
    • Findlay L, Sharp G, Fox B, et al. Endothelial cells co-stimulate peripheral blood mononuclear cell responses to monoclonal antibody TGN1412 in culture. Cytokine. 2011;55(1):141-151.
    • (2011) Cytokine , vol.55 , Issue.1 , pp. 141-151
    • Findlay, L.1    Sharp, G.2    Fox, B.3
  • 29
    • 0032777788 scopus 로고    scopus 로고
    • Immunobiology of human vascular endothelium
    • Pober JS. Immunobiology of human vascular endothelium. Immunol Res. 19(2-3):225-232, 1999. (Pubitemid 29401379)
    • (1999) Immunologic Research , vol.19 , Issue.2-3 , pp. 225-232
    • Pober, J.S.1
  • 30
    • 0031705761 scopus 로고    scopus 로고
    • Endothelial cells as antigen-presenting cells: Role in human transplant rejection
    • DOI 10.1007/s000180050226
    • Rose ML. Endothelial cells as antigen-presenting cells: role in human transplant rejection. Cell Mol Life Sci. 1998;54(9):965-978. (Pubitemid 28461685)
    • (1998) Cellular and Molecular Life Sciences , vol.54 , Issue.9 , pp. 965-978
    • Rose, M.L.1
  • 31
    • 0028902423 scopus 로고
    • Human vascular endothelial cells process and present autoantigen to human T cell lines
    • Savage CO, Brooks CJ, Harcourt GC, et al. Human vascular endothelial cells process and present autoantigen to human T cell lines. Int Immunol. 1995;7(3):471-479.
    • (1995) Int Immunol. , vol.7 , Issue.3 , pp. 471-479
    • Savage, C.O.1    Brooks, C.J.2    Harcourt, G.C.3
  • 32
    • 0028337494 scopus 로고
    • Antigen presentation by human dermal microvascular endothelial cells: Immunoregulatory effect of IFN-gamma and IL-10
    • Vora M, Yssel H, de Vries JE, Karasek MA. Antigen presentation by human dermal microvascular endothelial cells. Immunoregulatory effect of IFN-gamma and IL-10. J Immunol. 1994;152(12):5734-5741. (Pubitemid 24174152)
    • (1994) Journal of Immunology , vol.152 , Issue.12 , pp. 5734-5741
    • Vora, M.1    Yssel, H.2    De Vries, J.E.3    Karasek, M.A.4
  • 33
    • 0025310546 scopus 로고
    • Endothelial cells augment T cell interleukin 2 production by a contact-dependent mechanism involving CD2/LFA-3 interaction
    • DOI 10.1084/jem.171.5.1453
    • Hughes CC, Savage CO, Pober JS. Endothelial cells augment T cell interleukin 2 production by a contact-dependent mechanism involving CD2/LFA-3 interaction. J Exp Med. 1990;171(5):1453-1467. (Pubitemid 20167543)
    • (1990) Journal of Experimental Medicine , vol.171 , Issue.5 , pp. 1453-1467
    • Hughes, C.C.W.1    Savage, C.O.S.2    Pober, J.S.3
  • 34
    • 0033840148 scopus 로고    scopus 로고
    • Vascular endothelial cells provide T cells with costimulatory signals via the OX40/gp34 system
    • Kunitomi A, Hori T, Imura A, Uchiyama T. Vascular endothelial cells provide T cells with costimulatory signals via the OX40/gp34 system. J Leukoc Biol. 2000;68(1):111-118.
    • (2000) J Leukoc Biol. , vol.68 , Issue.1 , pp. 111-118
    • Kunitomi, A.1    Hori, T.2    Imura, A.3    Uchiyama, T.4
  • 35
    • 79954577066 scopus 로고    scopus 로고
    • B7-h2 is a costimulatory ligand for CD28 in human
    • Yao S, Zhu Y, Zhu G, et al. B7-h2 is a costimulatory ligand for CD28 in human. Immunity. 2011;34(5):729-740.
    • (2011) Immunity , vol.34 , Issue.5 , pp. 729-740
    • Yao, S.1    Zhu, Y.2    Zhu, G.3
  • 40
    • 66949171812 scopus 로고    scopus 로고
    • Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOSdeficient patients
    • Takahashi N, Matsumoto K, Saito H, et al. Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOSdeficient patients. J Immunol. 2009;182(9):5515-5527.
    • (2009) J Immunol. , vol.182 , Issue.9 , pp. 5515-5527
    • Takahashi, N.1    Matsumoto, K.2    Saito, H.3
  • 41
    • 62449309334 scopus 로고    scopus 로고
    • Anti-CTLA-4 therapy results in higher CD4+ICOShi T cell frequency and IFN-gamma levels in both nonmalignant and malignant prostate tissues
    • Chen H, Liakou CI, Kamat A, et al. Anti-CTLA-4 therapy results in higher CD4+ICOShi T cell frequency and IFN-gamma levels in both nonmalignant and malignant prostate tissues. Proc Natl Acad Sci U S A. 2009;106(8):2729-2734.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.8 , pp. 2729-2734
    • Chen, H.1    Liakou, C.I.2    Kamat, A.3
  • 42
    • 54449091476 scopus 로고    scopus 로고
    • CTLA-4 blockade increases IFNgamma-producing CD4+ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients
    • Liakou CI, Kamat A, Tang DN, et al. CTLA-4 blockade increases IFNgamma-producing CD4+ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients. Proc Natl Acad Sci U S A. 2008;105(39):14987-14992.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.39 , pp. 14987-14992
    • Liakou, C.I.1    Kamat, A.2    Tang, D.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.