Curcuminoid analogs inhibit nitric oxide production from LPS-activated microglial cells

Journal of Natural Medicines

Volumn 66, Issue 2, 2012, Pages 400-405

  Tocharus, Jiraporn ^a   Jamsuwan, Sataporn ^b   Tocharus, Chainarong ^a   Changtam, Chatchawan ^c   Suksamrarn, Apichart ^c  

^a Faculty of Medicine Chiang Mai University   (Thailand)

^b NARESUAN UNIVERSITY   (Thailand)

^c RAMKHAMHAENG UNIVERSITY   (Thailand)

Author keywords

Curcuminoid analog; Di O demethylcurcumin; HAPI microglia; Inducible nitric oxide synthase; O Demethyldemethoxycurcumin

Indexed keywords

CURCUMIN; CURCUMINNOID DERIVATIVE; DEMETHOXYCURCUMIN; DI O DEMETHYLCURCUMIN; DIDEMETHOXYCURCUMIN; HEXAHYDROBISDEMETHOXYCURCUMIN; HEXAHYDROCURCUMIN; HEXAHYDRODEMETHOXYCURCUMIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; MONO O DEMETHYLCURCUMIN; NEUROPROTECTIVE AGENT; NITRIC OXIDE; TETRAHYDROBISDEMETHOXYCURCUMIN; TETRAHYDROCURCUMIN; TETRAHYDRODEMETHOXYCURCUMIN; UNCLASSIFIED DRUG; DRUG DERIVATIVE; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL ACTIVATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; GENE EXPRESSION; IC 50; MICROGLIA; NEUROPROTECTION; NONHUMAN; PHARMACOLOGICAL BLOCKING; RAT; ANIMAL; BIOSYNTHESIS; CELL LINE; CHEMISTRY; DRUG EFFECT; METABOLISM;

ANIMALS; CELL LINE; CURCUMIN; LIPOPOLYSACCHARIDES; MICROGLIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; RATS;

EID: 84863506806     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-011-0599-6     Document Type: Article

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