Gold nanoparticles conjugated with cisplatin/doxorubicin/capecitabine lower the chemoresistance of hepatocellular carcinoma-derived cancer cells

Journal of Gastrointestinal and Liver Diseases

Volumn 21, Issue 2, 2012, Pages 188-196

  Tomuleasa, Ciprian ^a,b,c   Soritau, Olga ^b   Orza, Anamaria ^c,d   Dudea, Mircea ^c,d   Petrushev, Bobe ^c   Mosteanu, Ofelia ^c   Susman, Sergiu ^e   Florea, Adrian ^c   Pall, Emoke ^c   Aldea, Mihaela ^c   Kacso, Gabriel ^b,f   Cristea, Victor ^c   Berindan Neagoe, Ioana ^c   Irimie, Alexandru ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Ion Chiricuta Comprehensive Cancer Center   (Romania)

^c IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^d BABE BOLYAI UNIVERSITY   (Romania)

^e Octavian Fodor Regional Institute of Gastroenterology and Hepatology   (Romania)

^f UNIVERSITY OF AGRICULTURAL SCIENCES AND VETERINARY MEDICINE   (Romania)

Author keywords

Cancer cells; Drug delivery systems; Gold nanostructures; Hepatocellular carcinoma

Indexed keywords

ASPARTIC ACID; CAPECITABINE; CAPECITABINE GOLD NANOPARTICLE ASPARTATE CONJUGATE; CISPLATIN; CISPLATIN GOLD NANOPARTICLE ASPARTATE CONJUGATE; DOXORUBICIN; DOXORUBICIN GOLD NANOPARTICLE ASPARTATE CONJUGATE; GOLD NANOPARTICLE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DEOXYCYTIDINE; DRUG DERIVATIVE; FLUOROURACIL; GOLD; METAL NANOPARTICLE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARCINOMA CELL; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFECT; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; APOPTOSIS; CELL DEATH; CELL PROLIFERATION; DRUG RESISTANCE; DRUG SCREENING; LIVER TUMOR; METHODOLOGY; PATHOLOGY; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL CULTURE; ULTRASTRUCTURE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL DEATH; CELL PROLIFERATION; CISPLATIN; DEOXYCYTIDINE; DOXORUBICIN; DRUG DELIVERY SYSTEMS; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; FLUOROURACIL; GOLD; HUMANS; LIVER NEOPLASMS; METAL NANOPARTICLES; MICROSCOPY, ELECTRON, TRANSMISSION; TUMOR CELLS, CULTURED;

EID: 84863481058     PISSN: 18418724     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Parkin DM, Bray F, Ferlay J, Pisani P. Estimating the world cancer burden: Globocan 2000. Int J Cancer 2001; 94: 153-156.
2. Bruix J, Sherman M; Practice Guidelines Committee, American Association for the Study of Liver Diseases. Management of hepatocellular carcinoma. Hepatology 2005; 42: 1208-1236.
3. Yang XR, Xu Y, Yu B, et al. High expression levels of putative hepatic stem/progenitor cell biomarkers related to tumour angiogenesis and poor prognosis of hepatocellular carcinoma. Gut 2010; 59: 953-962.
4. Yeo W, Mok TS, Zee B, et al. A randomized phase III study of doxorubicin versus cisplatin/Interferon f{hook}¿-2b/ Doxorubicin/ Fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma. J Natl Cancer Inst 2005; 97: 1532-1538.
5. Miklaova N, Fischer-Fodor E, Lonnecke P, et al. Antiproliferative effect of novel platinum(II) and palladium(II) complexes on hepatic tumor stem cells in vitro. Eur J Med Chem 2012;49:41-47.
6. Forner A, Llovet JM, Bruix J. Hepatocellular carcinoma. Lancet 2012;379:1245-1255.
7. Singal AK, Anand BS. Management of hepatitis C virus infection in HIV/HCV co-infected patients: clinical review. World J Gastroenterol 2009; 15: 3713-3724.
8. Sharma P, Saini SD, Kuhn LB, et al. Knowledge of hepatocellular carcinoma screening guidelines and clinical practices among gastroenterologist. Dig Dis Sci 2011; 56: 569-577.
9. Jelic S, Sotiropoulos GC; ESMO Guidelines Working Group. Hepatocellular carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2010; 21 Suppl 5: v59-v64.
10. Riehle KJ, Dan YY, Campbell JS, Fausto N. New concepts in liver regeneration. J Gastroenterol Hepatol 2011; 26 Suppl 1: 203-212.
11. Mukherjee P, Bhattacharya R, Wang, et al. Antiangiogenic properties of gold nanoparticles. Clin Cancer Res 2005; 11: 3530-3534.
12. Sinha R, Kim GJ, Nie S, Shin DM. Nanotechnology in cancer therapeutics: bioconjugated nanoparticles for drug delivery. Mol Cancer Ther 2006; 5: 1909-1917.
13. Ghosh P, Han G, De M, Kim CK, Rotello VM. Gold nanoparticles in delivery applications. Adv Drug Deliv Rev 2008; 60: 1307-1315.
14. Bartczak D, Kanaras AG. Preparation of peptide functionalized gold nanoparticles using one pot EDC/sulfo-NHS coupling. Langmuir 2011; 27: 10119-10123.
15. Oh JH, Lee JS. Salt concentration-induced dehybridisation of DNAgold nanoparticle conjugate assemblies for diagnostic applications. Chem Commun (Camb) 2010; 46: 6382-6384.
16. Yan B. Impacts of nanotechnology on medicinal chemistry and drug discovery. Curr Med Chem 2011; 18: 2044.
17. Lim ZZ, Li JE, Ng CT, Yung LY, Bay BH. Gold nanoparticles in cancer therapy. Acta Pharmacol Sin 2011; 32: 983-990.
18. Kudo M. The 2008 Okuda lecture: Management of hepatocellular carcinoma: from surveillance to molecular targeted therapy. J Gastroenterol Hepatol 2010; 25: 439-452.
19. Zhou H, Rogler LE, Teperman L, Morgan G, Rogler CE. Identification of hepatocytic and bile ductular cell lineages and candidate stem cells in bipolar ductular reactions in cirrhotic human liver. Hepatology 2007;45:716-724.
20. Tomuleasa C, Soritau O, Rus-Ciuca D, et al. Isolation and characterization of hepatic cancer cells with stem-like properties from hepatocellular carcinoma. J Gastrointestin Liver Dis 2010;19:61-67.
21. Wang P, Cong M, Liu TH, et al. Primary isolated hepatic oval cells maintain progenitor cell phenotypes after two-year prolonged cultivation. J Hepatol 2010;53:863-871.
22. Sasaki K, Kon J, Mizuguchi T, et al. Proliferation of hepatocyte progenitor cells isolated from adult human livers in serum-free medium. Cell Transplant 2008;17:1221-1230.
23. Wege H, Brummendorf TH. Telomerase activation in liver regeneration and hepatocarcinogenesis: Dr. Jekyll or Mr. Hyde? Curr Stem Cell Res Ther 2007;2:31-38.
24. Levy R, Shaheen U, Cesbron Y, See V. Gold nanoparticles delivery in mammalian live cells: a critical review. Nano Rev 2010; 1: 10.3402/nano.v1i0.4889.
25. Kah JC, Kho KW, Lee CG, et al. Early diagnosis of oral cancer based on the surface plasmon resonance of gold nanoparticles. Int J Nanomedicine 2007; 2: 785-798.
26. Ren L, Huang XL, Zhang B, et al. Cisplatin-loaded Au-Au2S nanoparticles for potential cancer therapy: cytotoxicity, in vitro carcinogenicity, and cellular uptake. J Biomed Mater Res A 2008; 85: 787-796.
27. Schaeffer N, Tan B, Dickinson C, et al. Fluorescent or not? Sizedependent fluorescence switching for polymer-stabilized gold clusters in the 1.1.1.7 nm size range. Chem Commun (Camb) 2008; 34: 3986-3988.
28. Guevel XL, Hotzer B, Jung G, Hollemeyer K, Trouillet V, Schneider M. Formation of fluorescent metal (Au, Ag) nanoclusters capped in bovine serum albumin followed by fluorescence and spectroscopy. J Phys Chem C 2011; 115: 10955-10963.
29. Wong R, Frenette C. Updates in the management of hepatocellular carcinoma. Gastroenterol Hepatol (N Y) 2011; 7: 16-24.
30. Rampone B, Schiavone B, Martino A, Viviano C, Confuorto G. Current management strategy of hepatocellular carcinoma. World J Gastroenterol 2009; 15: 3210-3216.
31. Leung TW, Patt YZ, Lau WY, et al. Complete pathological remission is possible with systemic combination chemotherapy for inoperable hepatocellular carcinoma. Clin Cancer Res 1999; 5: 1676-1681.
32. Yeo W, Mok TS, Zee B, et al. A randomized phase III study of doxorubicin versus cisplatin/interferon alpha-2b/doxorubicin/ fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma. J Natl Cancer Inst 2005; 97: 1532-1538.
33. Quante M, Wang TC. Stem cells in gastroenterology and hepatology. Nat Rev Gastroenterol Hepatol 2009; 6: 724-737.
34. Nicolis SK. Cancer stem cells and "stemness" genes in neurooncology. Neurobiol Dis 2007; 25: 217-229.
35. Kettenbach J, Stadler A, Katzler IV, et al. Drug-loaded microspheres for the treatment of liver cancer: review of current results. Cardiovasc Intervent Radiol 2008; 31: 468-476.
36. Bae WK, Lee JH, Lee SJ, et al. Enhanced anti-cancer effect of 5-fluorouracil loaded into thermo-responsive conjugated linoleic acid-incorporated poloxamer hydrogel on metastatic colon cancer models. J Nanosci Nanotechnol 2011; 11: 1425-1428.
37. Xu Y, Mahmood M, Li Z, et al. Cobalt nanoparticles coated with graphitic shells as localized radio frequency absorbers for cancer therapy. Nanotechnology 2008; 19: 435102.
38. Mahmood M, Casciano DA, Mocan T, et al. Cytotoxicity and biological effects of functional nanomaterials delivered to various cell lines. J Appl Toxicol 2010; 30: 74-83.