Enhanced anti-cancer effect of 5-fluorouracil loaded into thermo-responsive conjugated linoleic acid-incorporated poloxamer hydrogel on metastatic colon cancer models

Journal of Nanoscience and Nanotechnology

Volumn 11, Issue 2, 2011, Pages 1425-1428

  Bae, Woo Kyun ^a   Lee, Ji Hee ^a   Lee, Sang Joon ^b   Park, Myong Suk ^a   Hwang, Jun Eul ^a   Shim, Hyun Jeong ^a   Cho, Sang Hee ^a   Guo, Ding Ding ^c   Cho, Chong Su ^c   Park, In Kyu ^b   Chung, Ik Joo ^a  

^a Chonnam National University   (South Korea)

^b Chonnam National University Medical School   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

5 fluorouracil; Colon cancer; Conjugated linoleic acid coupled pluronic F127

Indexed keywords

5-FLUOROURACIL; ANTICANCER ACTIVITIES; COLON CANCER; CONJUGATED LINOLEIC ACID-COUPLED PLURONIC F127; DRUG DELIVERY SYSTEM; IN-VIVO; INTRAPERITONEAL; LINOLEIC; PLURONIC F-127; POLOXAMER; THERMO-RESPONSIVE; TUMOR GROWTH;

CELL DEATH; DISEASES; DRUG DELIVERY; HYDROGELS; UNSATURATED FATTY ACIDS;

LINOLEIC ACID;

ANTINEOPLASTIC AGENT; CASP3 PROTEIN, MOUSE; CASPASE 3; CONJUGATED LINOLEIC ACID; FLUOROURACIL; POLOXAMER; PROTEIN BCL 2;

ANIMAL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; COLON TUMOR; DRUG DELIVERY SYSTEM; DRUG EFFECT; HYDROGEL; LIVER TUMOR; METABOLISM; METASTASIS; MOUSE; NANOTECHNOLOGY; PATHOLOGY; PERITONEUM TUMOR; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; COLONIC NEOPLASMS; DRUG DELIVERY SYSTEMS; FLUOROURACIL; HYDROGELS; LINOLEIC ACIDS, CONJUGATED; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; NANOTECHNOLOGY; PERITONEAL NEOPLASMS; POLOXAMER; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 79954994739     PISSN: 15334880     EISSN: None     Source Type: Journal    
DOI: 10.1166/jnn.2011.3403     Document Type: Conference Paper

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