Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation

Protein and Cell

Volumn 3, Issue 6, 2012, Pages 434-440

  Liu, Yan ^a   Zhu, Yun ^a   Ye, Sheng ^a   Zhang, Rongguang ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

Author keywords

cell adhesion; crystal structure; integrin; kindlin 2; membrane; PH domain

Indexed keywords

FERM DOMAIN CONTAING PROTEIN; INTEGRIN; KINDLIN 2 PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; GENE INSERTION; MEMBRANE BINDING; PLECKSTRIN HOMOLOGY DOMAIN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE;

EID: 84863477602     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-012-2046-1     Document Type: Article

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