Interleukin-9 receptor gene is transcriptionally regulated by nucleolin in T-Cell lymphoma cells

Molecular Carcinogenesis

Volumn 51, Issue 8, 2012, Pages 619-627

  Shang, Yi ^a,b   Kakinuma, Shizuko ^a   Nishimura, Mayumi ^a   Kobayashi, Yoshiro ^b   Nagata, Kisaburo ^b   Shimada, Yoshiya ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b TOHO UNIVERSITY   (Japan)

Author keywords

Il9r; Nucleolin; T cell lymphoma

Indexed keywords

INTERLEUKIN 9 RECEPTOR; NUCLEOLIN;

5' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; AT RICH SEQUENCE; CELL NUCLEUS; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN STRUCTURE; DNA FLANKING REGION; FEMALE; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; T CELL LYMPHOMA; TRANSCRIPTION REGULATION;

5' FLANKING REGION; AMINO ACID SEQUENCE; ANIMALS; AT RICH SEQUENCE; BASE SEQUENCE; BLOTTING, WESTERN; CELL NUCLEUS; CHROMATIN IMMUNOPRECIPITATION; DNA, NEOPLASM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; IMMUNOHISTOCHEMISTRY; LYMPHOMA, T-CELL; MALE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, INTERLEUKIN-9; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA-BINDING PROTEINS; TUMOR CELLS, CULTURED;

EID: 84863476207     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20834     Document Type: Article

References (32)

1. Nakase K, Kita K, Miwa H, et al. Clinical and prognostic significance of cytokine receptor expression in adult acute lymphoblastic leukemia: Interleukin-2 receptor alpha-chain predicts a poor prognosis. Leukemia 2007; 21: 326-332.
2. Testa U, Riccioni R, Diverio D, Rossini A, Lo Coco F, Peschle C. Interleukin-3 receptor in acute leukemia. Leukemia 2004; 18: 219-226.
3. Barata JT, Keenan TD, Silva A, Nadler LM, Boussiotis VA, Cardoso AA. Common gamma chain-signaling cytokines promote proliferation of T-cell acute lymphoblastic leukemia. Haematologica 2004; 89: 1459-1467.
4. Gruss HJ, Brach MA, Drexler HG, Bross KJ, Herrmann F. Interleukin 9 is expressed by primary and cultured Hodgkin and Reed-Sternberg cells. Cancer Res 1992; 52: 1026-1031.
5. Nagato T, Kobayashi H, Kishibe K, et al. Expression of interleukin-9 in nasal natural killer/T-cell lymphoma cell lines and patients. Clin Cancer Res 2005; 11: 8250-8257.
6. Matsushita K, Arima N, Ohtsubo H, et al. Frequent expression of interleukin-9 mRNA and infrequent involvement of interleukin-9 in proliferation of primary adult T-cell leukemia cells and HTLV-I infected T-cell lines. Leuk Res 1997; 21: 211-216.
7. Glimelius I, Edstrom A, Amini RM, et al. IL-9 expression contributes to the cellular composition in Hodgkin lymphoma. Eur J Haematol 2006; 76: 278-283.
8. Houssiau FA, Renauld JC, Stevens M, et al. Human T cell lines and clones respond to IL-9. J Immunol 1993; 150: 2634-2640.
9. Renauld JC, Vink A, Louahed J, Van Snick J. Interleukin-9 is a major anti-apoptotic factor for thymic lymphomas. Blood 1995; 85: 1300-1305.
10. Shang Y, Kakinuma S, Amasaki Y, Nishimura M, Kobayashi Y, Shimada Y. Aberrant activation of interleukin-9 receptor and downstream Stat3/5 in primary T-cell lymphomas in vivo in susceptible B6 and resistant C3H mice. In Vivo 2008; 22: 713-720.
11. Nishimura M, Kakinuma S, Yamamoto D, et al. Elevated interleukin-9 receptor expression and response to interleukins-9 and -7 in thymocytes during radiation-induced T-cell lymphomagenesis in B6C3F1 mice. J Cell Physiol 2004; 198: 82-90.
12. Chang MS, Engel G, Benedict C, Basu R, McNinch J. Isolation and characterization of the human interleukin-9 receptor gene. Blood 1994; 83: 3199-3205.
13. Suda T, Murray R, Fischer M, Yokota T, Zlotnik A. Tumor necrosis factor-alpha and P40 induce day 15 murine fetal thymocyte proliferation in combination with IL-2. J Immunol 1990; 144: 1783-1787.
14. De Smedt M, Verhasselt B, Kerre T, et al. Signals from the IL-9 receptor are critical for the early stages of human intrathymic T cell development. J Immunol 2000; 164: 1761-1767.
15. Peng X, Mehta RG, Tonetti DA, Christov K. Identification of novel RARbeta2 transcript variants with short 5′-UTRs in normal and cancerous breast epithelial cells. Oncogene 2005; 24: 1296-1301.
16. Orrick LR, Olson MO, Busch H. Comparison of nucleolar proteins of normal rat liver and Novikoff hepatoma ascites cells by two-dimensional polyacrylamide gel electrophoresis. Proc Natl Acad Sci USA 1973; 70: 1316-1320.
17. Bugler B, Caizergues-Ferrer M, Bouche G, Bourbon H, Amalric F. Detection and localization of a class of proteins immunologically related to a 100-kDa nucleolar protein. Eur J Biochem 1982; 128: 475-480.
18. Tuteja R, Tuteja N. Nucleolin: A multifunctional major nucleolar phosphoprotein. Crit Rev Biochem Mol Biol 1998; 33: 407-436.
19. Grinstein E, Du Y, Santourlidis S, Christ J, Uhrberg M, Wernet P. Nucleolin regulates gene expression in CD34-positive hematopoietic cells. J Biol Chem 2007; 282: 12439-12449.
20. Samuel S, Twizere JC, Beifuss KK, Bernstein LR. Nucleolin binds specifically to an AP-1 DNA sequence and represses AP1-dependent transactivation of the matrix metalloproteinase-13 gene. Mol Carcinog 2008; 47: 34-46.
21. Tsou JH, Chang KY, Wang WC, et al. Nucleolin regulates c-Jun/Sp1-dependent transcriptional activation of cPLA2alpha in phorbol ester-treated non-small cell lung cancer A549 cells. Nucleic Acids Res 2008; 36: 217-227.
22. Huddleson JP, Ahmad N, Lingrel JB. Up-regulation of the KLF2 transcription factor by fluid shear stress requires nucleolin. J Biol Chem 2006; 281: 15121-15128.
23. Sharma S, Kelly TK, Jones PA. Epigenetics in cancer. Carcinogenesis 2010; 31: 27-36.
24. Kakinuma S, Nishimura M, Sasanuma S, et al. Spectrum of Znfn1a1 (Ikaros) inactivation and its association with loss of heterozygosity in radiogenic T-cell lymphomas in susceptible B6C3F1 mice. Radiat Res 2002; 157: 331-340.
25. Kim J, Sif S, Jones B, et al. Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity 1999; 10: 345-355.
26. Koipally J, Kim J, Jones B, et al. Ikaros chromatin remodeling complexes in the control of differentiation of the hemo-lymphoid system. Cold Spring Harb Symp Quant Biol 1999; 64: 79-86.
27. Lopez-Nieva P, Santos J, Fernandez-Piqueras J. Defective expression of Notch1 and Notch2 in connection to alterations of c-Myc and Ikaros in gamma-radiation-induced mouse thymic lymphomas. Carcinogenesis 2004; 25: 1299-1304.
28. Angelov D, Bondarenko VA, Almagro S, et al. Nucleolin is a histone chaperone with FACT-like activity and assists remodeling of nucleosomes. EMBO J 2006; 25: 1669-1679.
29. Otake Y, Soundararajan S, Sengupta TK, et al. Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA. Blood 2007; 109: 3069-3075.
30. Zhang J, Tsaprailis G, Bowden GT. Nucleolin stabilizes Bcl-X L messenger RNA in response to UVA irradiation. Cancer Res 2008; 68: 1046-1054.
31. Ishimaru D, Ramalingam S, Sengupta TK, et al. Regulation of Bcl-2 expression by HuR in HL60 leukemia cells and A431 carcinoma cells. Mol Cancer Res 2009; 7: 1354-1366.
32. Zhang B, Wang H, Jiang B, et al. Nucleolin/C23 is a negative regulator of hydrogen peroxide-induced apoptosis in HUVECs. Cell Stress Chaperones 2010; 15: 249-257.