Identification of novel RARβ2 transcript variants with short 5′-UTRs in normal and cancerous breast epithelial cells

Oncogene

Volumn 24, Issue 7, 2005, Pages 1296-1301

  Peng, Xinjian ^a,b   Mehta, Rajendra G ^a,b   Tonetti, Debra A ^a   Christov, Konstantin ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b IIT RESEARCH INSTITUTE   (United States)

Author keywords

5 UTR; Breast cancer; RAR 2; Transcript variants; Translation

Indexed keywords

MESSENGER RNA; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID;

5' UNTRANSLATED REGION; ARTICLE; BREAST CANCER; CELL STRAIN MCF 7; CONTROLLED STUDY; GENE IDENTIFICATION; HUMAN; HUMAN CELL; OPEN READING FRAME; PRIORITY JOURNAL; PROMOTER REGION; RARBETA2 GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSLATION REGULATION; TUMOR SUPPRESSOR GENE; BREAST TUMOR; CELL LINE; DRUG EFFECT; EPITHELIUM CELL; GENETIC TRANSCRIPTION; GENETICS; MAMMARY GLAND; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN SYNTHESIS; TRANSCRIPTION INITIATION SITE; UPREGULATION;

5' UNTRANSLATED REGIONS; BASE SEQUENCE; BREAST NEOPLASMS; CELL LINE; EPITHELIAL CELLS; GENES, TUMOR SUPPRESSOR; HUMANS; MAMMARY GLANDS, HUMAN; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PROMOTER REGIONS (GENETICS); PROTEIN BIOSYNTHESIS; RECEPTORS, RETINOIC ACID; RETINOIDS; RNA, MESSENGER; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC; TRETINOIN; UP-REGULATION;

EID: 14644415917     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208284     Document Type: Article

References (22)

1. Carmichael J, DeGraff WG, Gazdar AF, Minna JD and Mitchell JB. (1987). Cancer Res., 47, 936-942.
2. Chambon P. (1996). FASEB J., 10, 940-954.
3. Chen LI, Sommer K and Swisshelm K. (2002). J. Biol. Chem., 277, 35411-35421.
4. Deng G, Lu Y, Zlotnikov G, Thor AD and Smith HS. (1996). Science, 249, 1577-1580.
5. de The H, Marchio A, Tiollais P and Dejean A. (1987). Nature, 330, 667-670.
6. Giguere V. (1994). Endocr. Rev., 15, 61-79.
7. Gray NK and Wickens M. (1998). Annu. Rev. Cell Dev. Biol., 14, 399-458.
8. Leroy P, Krust A, Zelent A, Mendelsohn C, Garnier JM, Kastner P, Dierich A and Chambon P. (1991). EMBO J., 10, 59-69.
9. Li XS, Shao ZM, Sheikh MS, Eiseman JL, Sentz D, Jetten AM, Chen JC, Dawson MI, Aisner S, Rishi AK, Gutierrez P, Schnapper L and Fontana JA. (1995). J Cell. Physiol., 165, 449-458.
10. Lippman SM, Heyman RA and Kurie JM. (1995). J. Cell. Biochem., 22 (Suppl), 1-10.
11. Lotan R. (1996). FASEB J., 10, 1031-1039.
12. Peng X, Maruo T, Cao Y, Punj V, Mehta R, Das Gupta TK and Christov K. (2004a). Cancer Res. (in press).
13. Peng X, Yun D and Christov K. (2004b). Int. J. Oncol., 25, 961-971.
14. Santner SJ, Dawson PJ, Tait L, Soule HD, Eliason J, Mohamed AN, Wolman SR, Heppner GH and Miller FR. (2001). Breast Cancer Res. Treat., 65, 101-110.
15. Sirchia SM, Ferguson AT, Sironi E, Subramanyan A, Orlandi R, Sukumar S and Sacchi N. (2000). Oncogene, 19, 1556-1563.
16. Sommer KM, Chen LI, Treuting PM, Smith LT and Swisshelm K. (1999). Proc. Natl. Acad. Sci. USA, 96, 8651-8656.
17. Swisshelm K, Ryan K, Lee X, Tsou HC, Peacocke M and Sager R. (1994). Cell Growth Differ., 5, 133-141.
18. Tallman MS and Wiernik PH. (1992). J. Clin. Pharmacol., 32, 868-888.
19. Widschwendter M, Berger J, Daxenbichler G, Muller-Holzner E, Widschwendter A, Mayr A, Marth C and Zeimet AG. (1997). Cancer Res., 57, 4158-4161.
20. Xu XC, Sneige N, Liu X, Nandagiri R, Lee JJ, Lukmanji F, Hortobagyi G, Lippman SM, Dhingra K and Lotan R. (1997). Cancer Res., 57, 4992-4996.
21. Zelent A, Mendelsohn P, Kastner P, Krust A, Garnier JM, Ruffenach F, Leroy P and Chambon P. (1991). EMBO J., 10, 71-81.
22. Zimmer A, Zimmer AM and Reynolds K. (1994). J. Cell Biol., 27, 1111-1119.