-
1
-
-
0042195820
-
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts
-
Parrinello S, Samper E, Krtolica A, Goldstein J, Melov S, Campisi J. Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts. Nat Cell Biol. 2003; 5:741-747.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 741-747
-
-
Parrinello, S.1
Samper, E.2
Krtolica, A.3
Goldstein, J.4
Melov, S.5
Campisi, J.6
-
2
-
-
84859483420
-
Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin
-
(Albany NY)
-
Velarde MC, Flynn JM, Day NU, Melov S, Campisi J. Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin. Aging (Albany NY). 2012.
-
(2012)
Aging
-
-
Velarde, M.C.1
Flynn, J.M.2
Day, N.U.3
Melov, S.4
Campisi, J.5
-
3
-
-
79960286223
-
Signal transduction by reactive oxygen species
-
Finkel T. Signal transduction by reactive oxygen species. J Cell Biol. 2011; 194:7-15.
-
(2011)
J Cell Biol
, vol.194
, pp. 7-15
-
-
Finkel, T.1
-
4
-
-
33749986298
-
Free radicals and antioxidants in normal physiological functions and human disease
-
Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol. 2007; 39:44-84.
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 44-84
-
-
Valko, M.1
Leibfritz, D.2
Moncol, J.3
Cronin, M.T.4
Mazur, M.5
Telser, J.6
-
5
-
-
77951977494
-
Role of oxidatively induced DNA lesions in human pathogenesis
-
Sedelnikova OA, Redon CE, Dickey JS, Nakamura AJ, Georgakilas AG, Bonner WM. Role of oxidatively induced DNA lesions in human pathogenesis. Mutat Res. 2010; 704:152-159.
-
(2010)
Mutat Res
, vol.704
, pp. 152-159
-
-
Sedelnikova, O.A.1
Redon, C.E.2
Dickey, J.S.3
Nakamura, A.J.4
Georgakilas, A.G.5
Bonner, W.M.6
-
6
-
-
69949125332
-
Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence
-
Nakamura AJ, Chiang YJ, Hathcock KS, Horikawa I, Sedelnikova OA, Hodes RJ, Bonner WM. Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence. Epigenetics Chromatin. 2008; 1:6.
-
(2008)
Epigenetics Chromatin
, vol.1
, pp. 6
-
-
Nakamura, A.J.1
Chiang, Y.J.2
Hathcock, K.S.3
Horikawa, I.4
Sedelnikova, O.A.5
Hodes, R.J.6
Bonner, W.M.7
-
7
-
-
0035989388
-
Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster
-
Sun J, Folk D, Bradley TJ, Tower J. Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster. Genetics. 2002; 161:661-672.
-
(2002)
Genetics
, vol.161
, pp. 661-672
-
-
Sun, J.1
Folk, D.2
Bradley, T.J.3
Tower, J.4
-
8
-
-
33745473351
-
Defective mitochondrial gene expression results in reactive oxygen species-mediated inhibition of respiration and reduction of yeast life span
-
Bonawitz ND, Rodeheffer MS, Shadel GS. Defective mitochondrial gene expression results in reactive oxygen species-mediated inhibition of respiration and reduction of yeast life span. Mol Cell Biol. 2006; 26:4818-4829.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 4818-4829
-
-
Bonawitz, N.D.1
Rodeheffer, M.S.2
Shadel, G.S.3
-
9
-
-
34249667555
-
Effects of deleting mitochondrial antioxidant genes on life span
-
Unlu ES, Koc A. Effects of deleting mitochondrial antioxidant genes on life span. Ann N Y Acad Sci. 2007; 1100:505-509.
-
(2007)
Ann N Y Acad Sci
, vol.1100
, pp. 505-509
-
-
Unlu, E.S.1
Koc, A.2
-
10
-
-
12144288373
-
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging
-
Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, Alderson NL, Baynes JW, Epstein CJ, Huang TT, Nelson J, Strong R, Richardson A. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiol Genomics. 2003; 16:29-37.
-
(2003)
Physiol Genomics
, vol.16
, pp. 29-37
-
-
Van Remmen, H.1
Ikeno, Y.2
Hamilton, M.3
Pahlavani, M.4
Wolf, N.5
Thorpe, S.R.6
Alderson, N.L.7
Baynes, J.W.8
Epstein, C.J.9
Huang, T.T.10
Nelson, J.11
Strong, R.12
Richardson, A.13
-
11
-
-
29144458899
-
Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production
-
Trifunovic A, Hansson A, Wredenberg A, Rovio AT, Dufour E, Khvorostov I, Spelbrink JN, Wibom R, Jacobs HT, Larsson NG. Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production. Proc Natl Acad Sci U S A. 2005; 102:17993-17998.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 17993-17998
-
-
Trifunovic, A.1
Hansson, A.2
Wredenberg, A.3
Rovio, A.T.4
Dufour, E.5
Khvorostov, I.6
Spelbrink, J.N.7
Wibom, R.8
Jacobs, H.T.9
Larsson, N.G.10
-
12
-
-
77953627194
-
Somatic mitochondrial DNA mutations in mammalian aging
-
Larsson NG. Somatic mitochondrial DNA mutations in mammalian aging. Annu Rev Biochem. 2010; 79:683-706.
-
(2010)
Annu Rev Biochem
, vol.79
, pp. 683-706
-
-
Larsson, N.G.1
-
13
-
-
70350439125
-
Overexpression of Mn superoxide dismutase does not increase life span in mice
-
Jang YC, Perez VI, Song W, Lustgarten MS, Salmon AB, Mele J, Qi W, Liu Y, Liang H, Chaudhuri A, Ikeno Y, Epstein CJ, Van Remmen H, Richardson A. Overexpression of Mn superoxide dismutase does not increase life span in mice. J Gerontol A Biol Sci Med Sci. 2009; 64:1114-1125.
-
(2009)
J Gerontol A Biol Sci Med Sci
, vol.64
, pp. 1114-1125
-
-
Jang, Y.C.1
Perez, V.I.2
Song, W.3
Lustgarten, M.S.4
Salmon, A.B.5
Mele, J.6
Qi, W.7
Liu, Y.8
Liang, H.9
Chaudhuri, A.10
Ikeno, Y.11
Epstein, C.J.12
Van Remmen, H.13
Richardson, A.14
-
14
-
-
61449184625
-
Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans
-
Van Raamsdonk JM, Hekimi S. Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans. PLoS Genet. 2009; 5:e1000361.
-
(2009)
PLoS Genet
, vol.5
-
-
Van Raamsdonk, J.M.1
Hekimi, S.2
-
15
-
-
23844456959
-
Manganese superoxide dismutase induces p53-dependent senescence in colorectal cancer cells
-
Behrend L, Mohr A, Dick T, Zwacka RM. Manganese superoxide dismutase induces p53-dependent senescence in colorectal cancer cells. Mol Cell Biol. 2005; 25:7758-7769.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 7758-7769
-
-
Behrend, L.1
Mohr, A.2
Dick, T.3
Zwacka, R.M.4
-
16
-
-
0027365312
-
Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species
-
Ku HH, Brunk UT, Sohal RS. Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species. Free Radic Biol Med. 1993; 15:621-627.
-
(1993)
Free Radic Biol Med
, vol.15
, pp. 621-627
-
-
Ku, H.H.1
Brunk, U.T.2
Sohal, R.S.3
-
17
-
-
80054746755
-
The role of mitochondria in neurodegenerative diseases
-
Filosto M, Scarpelli M, Cotelli MS, Vielmi V, Todeschini A, Gregorelli V, Tonin P, Tomelleri G, Padovani A. The role of mitochondria in neurodegenerative diseases. J Neurol. 2011; 258:1763-1774.
-
(2011)
J Neurol
, vol.258
, pp. 1763-1774
-
-
Filosto, M.1
Scarpelli, M.2
Cotelli, M.S.3
Vielmi, V.4
Todeschini, A.5
Gregorelli, V.6
Tonin, P.7
Tomelleri, G.8
Padovani, A.9
|