Update in asthma 2011

American Journal of Respiratory and Critical Care Medicine

Volumn 186, Issue 1, 2012, Pages 35-40

  Kazani, Shamsah ^a   Israel, Elliot ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; CYTOKINE; NITRIC OXIDE;

ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CORTICOSTEROID THERAPY; DENDRITIC CELL; DISEASE EXACERBATION; DRUG SAFETY; ENVIRONMENTAL FACTOR; EOSINOPHIL; HEALTH CARE UTILIZATION; HOSPITALIZATION; HUMAN; LUNG FUNCTION; LUNG LAVAGE; MAST CELL; PRIORITY JOURNAL; RACE; REVIEW; SENSITIZATION; VOCAL CORD DISORDER;

ADRENERGIC BETA-AGONISTS; ANTIBODIES, MONOCLONAL; ASTHMA; CYTOKINES; DENDRITIC CELLS; DISEASE PROGRESSION; EOSINOPHILS; HUMANS; INTERLEUKIN-5; MAST CELLS; NITRIC OXIDE; PHENOTYPE; TREATMENT OUTCOME;

EID: 84863460325     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201204-0634UP     Document Type: Review

References (75)

1. (CDC) CfDCaP. Vital signs: asthma prevalence, disease characteristics, and self-management education: United States, 2001-2009. MMWR Morb Mortal Wkly Rep 2011;60:547-552.
2. Kazani S, Israel E. Update in asthma 2010. Am J Respir Crit Care Med 2011;184:291-296.
3. Wechsler ME, Castro M, Lehman E, Chinchilli VM, Sutherland ER, Denlinger L, Lazarus SC, Peters SP, Israel E, Network NACR. Impact of race on asthma treatment failures in the asthma clinical research network. Am J Respir Crit Care Med 2011;184:1247-1253.
4. Martinez FD, Chinchilli VM, Morgan WJ, Boehmer SJ, Lemanske RF, Mauger DT, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, et al. Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, double-blind, placebo-controlled trial. Lancet 2011;377:650-657.
5. Zeiger RS, Mauger D, Bacharier LB, Guilbert TW, Martinez FD, Lemanske RF, Strunk RC, Covar R, Szefler SJ, Boehmer S, et al.; CARE Network of the National Heart, Lung, and Blood Institute. Daily or intermittent budesonide in preschool children with recurrent wheezing. N Engl J Med 2011;365:1990-2001.
6. Hodyl NA, Stark MJ, Osei-Kumah A, Bowman M, Gibson P, Clifton VL. Fetal glucocorticoid-regulated pathways are not affected by inhaled corticosteroid use for asthma during pregnancy. Am J Respir Crit Care Med 2011;183:716-722.
7. O'Byrne PM, Pedersen S, Carlsson LG, Radner F, Thorén A, Peterson S, Ernst P, Suissa S. Risks of pneumonia in patients with asthma taking inhaled corticosteroids. Am J Respir Crit Care Med 2011;183: 589-595.
8. Price D, Musgrave SD, Shepstone L, Hillyer EV, Sims EJ, Gilbert RF, Juniper EF, Ayres JG, Kemp L, Blyth A, et al. Leukotriene antagonists as first-line or add-on asthma-controller therapy. N Engl J Med 2011;364:1695-1707.
9. Busse WW, Morgan WJ, Gergen PJ, Mitchell HE, Gern JE, Liu AH, Gruchalla RS, Kattan M, Teach SJ, Pongracic JA, et al. Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children. N Engl J Med 2011;364:1005-1015.
10. Wechsler ME, Kelley JM, Boyd IO, Dutile S, Marigowda G, Kirsch I, Israel E, Kaptchuk TJ. Active albuterol or placebo, sham acupuncture, or no intervention in asthma. N Engl J Med 2011;365:119-126.
11. Ducharme FM, Zemek RL, Chalut D, McGillivray D, Noya FJ, Resendes S, Khomenko L, Rouleau R, Zhang X. Written action plan in pediatric emergency room improves asthma prescribing, adherence, and control. Am J Respir Crit Care Med 2011;183:195-203.
12. Bruzzese JM, Sheares BJ, Vincent EJ, Du Y, Sadeghi H, Levison MJ, Mellins RB, Evans D. Effects of a school-based intervention for urban adolescents with asthma: a controlled trial. Am J Respir Crit Care Med 2011;183:998-1006.
13. Tantisira KG, Lasky-Su J, Harada M, Murphy A, Litonjua AA, Himes BE, Lange C, Lazarus R, Sylvia J, Klanderman B, et al. Genomewide association between glcci1 and response to glucocorticoid therapy in asthma. N Engl J Med 2011;365:1173-1183.
14. Corren J, Lemanske RF, Hanania NA, Korenblat PE, Parsey MV, Arron JR, Harris JM, Scheerens H, Wu LC, Su Z, et al. Lebrikizumab treatment in adults with asthma. N Engl J Med 2011;365:1088-1098.
15. Haldar P, Brightling CE, Hargadon B, Gupta S, Monteiro W, Sousa A, Marshall RP, Bradding P, Green RH, Wardlaw AJ, et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med 2009;360:973-984.
16. Nair P, Pizzichini MM, Kjarsgaard M, Inman MD, Efthimiadis A, Pizzichini E, Hargreave FE, O'Byrne PM.Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N Engl J Med 2009;360: 985-993.
17. Castro M, Mathur S, Hargreave F, Boulet LP, Xie F, Young J, Wilkins HJ, Henkel T, Nair P; Res-5-0010 Study Group. Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study. Am J Respir Crit Care Med 2011;184:1125-1132.
18. Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X, D'Agostino R Jr, Castro M, Curran-Everett D, Fitzpatrick AM, et al. Identification of asthma phenotypes using cluster analysis in the severe asthma research program. Am J Respir Crit Care Med 2010;181: 315-323.
19. Fitzpatrick AM, Teague WG, Meyers DA, Peters SP, Li X, Li H,Wenzel SE, Aujla S, Castro M, Bacharier LB, Gaston BM, Bleecker ER, Moore WC; National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program. Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute severe asthma research program. J Allergy Clin Immunol 2011;127:382-389.e1-e13.
20. Low K, Lau KK, Holmes P, Crossett M, Vallance N, Phyland D, Hamza K, Hamilton G, Bardin PG. Abnormal vocal cord function in difficult-to-treat asthma. Am J Respir Crit Care Med 2011;184:50-56.
21. Kiljander TO, Junghard O, Beckman O, Lind T. Effect of esomeprazole 40 mg once or twice daily on asthma a randomized, placebo-controlled study. Am J Respir Crit Care Med 2010;181:1042-1048.
22. Holbrook JT, Wise RA, Gold BD, Blake K, Brown ED, Castro M, Dozor AJ, Lima JJ, Mastronarde JG, Sockrider MM, et al.; Centers WCftALAACR. Lansoprazole for children with poorly controlled asthma: a randomized controlled trial. JAMA 2012;307:373-381.
23. Van Sickle D, Magzamen S, Mullahy J. Understanding socioeconomic and racial differences in adult lung function. Am J Respir Crit Care Med 2011;184:521-527.
24. Zhang Y, McConnell R, Gilliland F, Berhane K. Ethnic differences in the effect of asthma on pulmonary function in children. Am J Respir Crit Care Med 2011;183:596-603.
25. Verrills NM, Irwin JA, He XY, Wood LG, Powell H, Simpson JL, McDonald VM, Sim A, Gibson PG. Identification of novel diagnostic biomarkers for asthma and chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2011;183:1633-1643.
26. Cottrell L, Neal WA, Ice C, Perez MK, Piedimonte G. Metabolic abnormalities in children with asthma. Am J Respir Crit Care Med 2011; 183:441-448.
27. Lee SH, Kim KH, Kim JM, Yoon SH, Kim TH, Park SW, Park JS, Uh ST, Lee HS, Kim YH. Relationship between group-specific component protein and the development of asthma. Am J Respir Crit Care Med 2011;184:528-536.
28. Turner S, Prabhu N, Danielan P, McNeill G, Craig L, Allan K, Cutts R, Helms P, Seaton A, Devereux G. First- and second-trimester fetal size and asthma outcomes at age 10 years. Am J Respir Crit Care Med 2011; 184:407-413.
29. Camargo CA, Ingham T, Wickens K, Thadhani R, Silvers KM, Epton MJ, Town GI, Pattemore PK, Espinola JA, Crane J; Group NZAaACS. Cord-blood 25-hydroxyvitamin D levels and risk of respiratory infection, wheezing, and asthma. Pediatrics 2011;127:e180-e187.
30. Gupta A, Sjoukes A, Richards D, Banya W, Hawrylowicz C, Bush A, Saglani S. Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma. Am J Respir Crit Care Med 2011;184:1342-1349.
31. Macsali F, Real FG, Plana E, Sunyer J, Anto J, Dratva J, Janson C, Jarvis D, Omenaas ER, Zemp E, et al. Early age at menarche, lung function, and adult asthma. Am J Respir Crit Care Med 2011;183:8-14.
32. Denlinger LC, Sorkness RL, Lee WM, Evans MD, Wolff MJ, Mathur SK, Crisafi GM, Gaworski KL, Pappas TE, Vrtis RF, et al. Lower airway rhinovirus burden and the seasonal risk of asthma exacerbation. Am J Respir Crit Care Med 2011;184:1007-1014.
33. Innes AL, McGrath KW, Dougherty RH, McCulloch CE, Woodruff PG, Seibold MA, Okamoto KS, Ingmundson KJ, Solon MC, Carrington SD, et al. The H antigen at epithelial surfaces is associated with susceptibility to asthma exacerbation. Am J Respir Crit Care Med 2011; 183:189-194.
34. Lindesmith L, Moe C, Marionneau S, Ruvoen N, Jiang X, Lindblad L, Stewart P, LePendu J, Baric R. Human susceptibility and resistance to norwalk virus infection. Nat Med 2003;9:548-553. (Pubitemid 36597100)
35. Chawes BL, Bønnelykke K, Bisgaard H. Elevated eosinophil protein X in urine from healthy neonates precedes development of atopy in the first 6 years of life. Am J Respir Crit Care Med 2011;184:656-661.
36. Broekema M, Timens W, Vonk JM, Volbeda F, Lodewijk ME, Hylkema MN, Ten Hacken NH, Postma DS. Persisting remodeling and less airway wall eosinophil activation in complete remission of asthma. Am J Respir Crit Care Med 2011;183:310-316.
37. Fattouh R, Al-Garawi A, Fattouh M, Arias K, Walker TD, Goncharova S, Coyle AJ, Humbles AA, Jordana M. Eosinophils are dispensable for allergic remodeling and immunity in a model of house dust mite-induced airway disease. Am J Respir Crit Care Med 2011;183:179-188.
38. Balzar S, Fajt ML, Comhair SA, Erzurum SC, Bleecker E, Busse WW, Castro M, Gaston B, Israel E, Schwartz LB, et al. Mast cell phenotype, location, and activation in severe asthma: data from the Severe Asthma Research Program. Am J Respir Crit Care Med 2011;183:299-309.
39. Kearley J, Erjefalt JS, Andersson C, Benjamin E, Jones CP, Robichaud A, Pegorier S, Brewah Y, Burwell TJ, Bjermer L, et al. IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways. Am J Respir Crit Care Med 2011;183:865-875.
40. Bryce PJ. Revolution 9: the backwards and forwards evidence surrounding interleukin-9. Am J Respir Crit Care Med 2011;183:834-835.
41. Mouthuy J, Detry B, Sohy C, Pirson F, Pilette C. Presence in sputum of functional dust mite-specific IgE antibodies in intrinsic asthma. Am J Respir Crit Care Med 2011;184:206-214.
42. Camarda LE, Grayson MH. Can specific IgE discriminate between intrinsic and atopic asthma? Am J Respir Crit Care Med 2011;184:152-153.
43. van Rijt LS, Vos N, Willart M, Muskens F, Tak PP, van der Horst C, Hoogsteden HC, Lambrecht BN. Persistent activation of dendritic cells after resolution of allergic airway inflammation breaks tolerance to inhaled allergens in mice. Am J Respir Crit Care Med 2011;184:303-311.
44. Schwarze J, Mackenzie KJ. Neosensitization to allergens after resolution of allergic airways inflammation: a new role for airway dendritic cells. Am J Respir Crit Care Med 2011;184:283-284.
45. Takagi T, Taguchi O, Toda M, Ruiz DB, Bernabe PG, D'Alessandro-Gabazza CN, Miyake Y, Kobayashi T, Aoki S, Chiba F, et al. Inhibition of allergic bronchial asthma by thrombomodulin is mediated by dendritic cells. Am J Respir Crit Care Med 2011;183:31-42.
46. Chang CJ, Yang YH, Liang YC, Chiu CJ, Chu KH, Chou HN, Chiang BL. A novel phycobiliprotein alleviates allergic airway inflammation by modulating immune responses. Am J Respir Crit Care Med 2011;183:15-25.
47. Ege MJ, Mayer M, Normand AC, Genuneit J, Cookson WO, Braun- Fahrländer C, Heederik D, Piarroux R, von Mutius E, Group GTS. Exposure to environmental microorganisms and childhood asthma. N Engl J Med 2011;364:701-709.
48. Herbst T, Sichelstiel A, Schär C, Yadava K, Bürki K, Cahenzli J, McCoy K, Marsland BJ, Harris NL. Dysregulation of allergic airway inflammation in the absence of microbial colonization. Am J Respir Crit Care Med 2011;184:198-205.
49. Cernadas M. It takes a microbiome: commensals, immune regulation, and allergy. Am J Respir Crit Care Med 2011;184:149-150.
50. Ingram JL, Huggins MJ, Church TD, Li Y, Francisco DC, Degan S, Firszt R, Beaver DM, Lugogo NL, Wang Y, et al. Airway fibroblasts in asthma manifest an invasive phenotype. Am J Respir Crit Care Med 2011;183:1625-1632.
51. Gauvreau GM, Boulet LP, Cockcroft DW, Fitzgerald JM, Carlsten C, Davis BE, Deschesnes F, Duong M, Durn BL, Howie KJ, et al. Effects of interleukin-13 blockade on allergen-induced airway responses in mild atopic asthma. Am J Respir Crit Care Med 2011;183:1007-1014.
52. Elias JA, Lee CG. IL-13 in asthma: the successful integration of lessons from mice and humans. Am J Respir Crit Care Med 2011;183:957-958.
53. Li H, Bradbury JA, Dackor RT, Edin ML, Graves JP, DeGraff LM, Wang PM, Bortner CD, Maruoka S, Lih FB, et al. Cyclooxygenase-2 regulates Th17 cell differentiation during allergic lung inflammation. Am J Respir Crit Care Med 2011;184:37-49.
54. Peebles RS. The ever-expanding role of prostanoids in regulating immune responses. Am J Respir Crit Care Med 2011;184:1-2.
55. Besnard AG, Sabat R, Dumoutier L, Renauld JC, Willart M, Lambrecht B, Teixeira MM, Charron S, Fick L, Erard F, et al. Dual role of IL-22 in allergic airway inflammation and its cross-talk with IL-17a. Am J Respir Crit Care Med 2011;183:1153-1163.
56. Wang YH, Voo KS, Liu B, Chen CY, Uygungil B, Spoede W, Bernstein JA, Huston DP, Liu YJ. A novel subset of cd4(+) T(h)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma. J Exp Med 2010;207: 2479-2491.
57. Michaeloudes C, Chang PJ, Petrou M, Chung KF. Transforming growth factor-b and nuclear factor E2-related factor 2 regulate antioxidant responses in airway smooth muscle cells: role in asthma. Am J Respir Crit Care Med 2011;184:894-903.
58. Kim SR, Lee KS, Park SJ, Min KH, Lee MH, Lee KA, Bartov O, Atlas D, Lee YC. A novel dithiol amide CB3 attenuates allergic airway disease through negative regulation of p38 mitogen-activated protein kinase. Am J Respir Crit Care Med 2011;183:1015-1024.
59. Font-Ribera L, Villanueva CM, Nieuwenhuijsen MJ, Zock JP, Kogevinas M, Henderson J. Swimming pool attendance, asthma, allergies, and lung function in the Avon Longitudinal Study of Parents and Children cohort. Am J Respir Crit Care Med 2011;183:582-588.
60. Bernard A, Voisin C, Sardella A. Con: Respiratory risks associated with chlorinated swimming pools: a complex pattern of exposure and effects. Am J Respir Crit Care Med 2011;183:570-572.
61. Holgate ST. The acetaminophen enigma in asthma. Am J Respir Crit Care Med 2011;183:147-148.
62. Beasley RW, Clayton TO, Crane J, Lai CK, Montefort SR, Mutius E, Stewart AW, Group IPTS. Acetaminophen use and risk of asthma, rhinoconjunctivitis, and eczema in adolescents: international study of asthma and allergies in childhood phase three. Am J Respir Crit Care Med 2011;183:171-178.
63. Amberbir A, Medhin G, Alem A, Britton J, Davey G, Venn A. The role of acetaminophen and geohelminth infection on the incidence of wheeze and eczema: a longitudinal birth-cohort study. Am J Respir Crit Care Med 2011;183:165-170.
64. Burgess JK, Boustany S, Moir LM, Weckmann M, Lau JY, Grafton K, Baraket M, Hansbro PM, Hansbro NG, Foster PS, et al. Reduction of tumstatin in asthmatic airways contributes to angiogenesis, inflammation, and hyperresponsiveness. Am J Respir Crit Care Med 2010; 181:106-115.
65. Imaoka H, Punia N, Irshad A, Ying S, Corrigan CJ, Howie K, O'Byrne PM, Gauvreau GM, Sehmi R. Lung homing of endothelial progenitor cells in humans with asthma after allergen challenge. Am J Respir Crit Care Med 2011;184:771-778.
66. Grainge CL, Lau LC, Ward JA, Dulay V, Lahiff G, Wilson S, Holgate S, Davies DE, Howarth PH. Effect of bronchoconstriction on airway remodeling in asthma. N Engl J Med 2011;364:2006-2015.
67. Atochina-Vasserman EN, Winkler C, Abramova H, Schaumann F, Krug N, Gow AJ, Beers MF, Hohlfeld JM. Segmental allergen challenge alters multimeric structure and function of surfactant protein D in humans. Am J Respir Crit Care Med 2011;183:856-864.
68. Dweik RA, Sorkness RL, Wenzel S, Hammel J, Curran-Everett D, Comhair SAA, Bleecker E, Busse W, Calhoun WJ, Castro M, et al. Use of exhaled nitric oxide measurement to identify a reactive, at-risk phenotype among patients with asthma. Am J Respir Crit Care Med 2010;181:1033-1041.
69. Olin AC, Rosengren A, Thelle DS, Lissner L, Toren K. Increased fraction of exhaled nitric oxide predicts new-onset wheeze in a general population. Am J Respir Crit Care Med 2010;181:324-327.
70. Breton CV, Byun HM, Wang X, Salam MT, Siegmund K, Gilliland FD. DNA methylation in the arginase-nitric oxide synthase pathway is associated with exhaled nitric oxide in children with asthma. Am J Respir Crit Care Med 2011;184:191-197.
71. Duan QL, Gaume BR, Hawkins GA, Himes BE, Bleecker ER, Klanderman B, Irvin CG, Peters SP, Meyers DA, Hanrahan JP, et al. Regulatory haplotypes in ARG1 are associated with altered bronchodilator response. Am J Respir Crit Care Med 2011;183:449-454.
72. Sott JA, North ML, Rafii M, Huang H, Pencharz P, Subbarao P, Belik J, Grasemann H. Asymmetric dimethylarginine is increased in asthma. Am J Respir Crit Care Med 2011;184:779-785.
73. Ritz T, Ayala ES, Trueba AF, Vance CD, Auchus RJ. Acute stressinduced increases in exhaled nitric oxide in asthma and their association with endogenous cortisol. Am J Respir Crit Care Med 2011;183: 26-30.
74. Vieira RP, Müller T, Grimm M, von Gernler V, Vetter B, Dürk T, Cicko S, Ayata CK, Sorichter S, Robaye B, et al. Purinergic receptor type 6 contributes to airway inflammation and remodeling in experimental allergic airway inflammation. Am J Respir Crit Care Med 2011;184: 215-223.
75. Ferreira MA, Matheson MC, Duffy DL, Marks GB, Hui J, Le Souëf P, Danoy P, Baltic S, Nyholt DR, Jenkins M, et al. Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. Lancet 2011;378: 1006-1014.