Urine interleukin-18 and cystatin-C as biomarkers of acute kidney injury in critically ill neonates

Pediatric Nephrology

Volumn 27, Issue 5, 2012, Pages 851-860

  Li, Yanhong ^a   Fu, Chenlu ^b   Zhou, Xiaofei ^b   Xiao, Zhihui ^b   Zhu, Xueming ^b   Jin, Meifang ^b   Li, Xiaozhong ^b   Feng, Xing ^b  

^a SOOCHOW UNIVERSITY   (China)

^b CHILDREN S HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

Acute kidney injury; Critically ill neonates; Diagnostic test; Urinary biomarkers; Urinary cystatin C; Urinary interleukin 18

Indexed keywords

BIOLOGICAL MARKER; CYSTATIN C; INTERLEUKIN 18;

ACUTE KIDNEY FAILURE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CRITICALLY ILL PATIENT; FEMALE; GESTATIONAL AGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MATURITY; NEWBORN; PREDICTION; PRIORITY JOURNAL; PROTEIN URINE LEVEL;

ACUTE KIDNEY INJURY; AGING; APGAR SCORE; BIOLOGICAL MARKERS; BIRTH WEIGHT; BODY WEIGHT; CRITICAL ILLNESS; CYSTATIN C; DATA COLLECTION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GESTATIONAL AGE; HUMANS; IMMUNOCHEMISTRY; INFANT, NEWBORN; INTERLEUKIN-18; LOGISTIC MODELS; MALE; PREDICTIVE VALUE OF TESTS; ROC CURVE; SEX CHARACTERISTICS;

EID: 84863454425     PISSN: 0931041X     EISSN: 1432198X     Source Type: Journal    
DOI: 10.1007/s00467-011-2072-x     Document Type: Article

References (40)

1. Askenazi DJ, Griffin R, McGwin G, Carlo W, Ambalavanan N (2009) Acute kidney injury is independently associated with mortality in very low birthweight infants: A matched case-control analysis. Pediatr Nephrol 24:991-997
2. Toth-Heyn P, Drukker A, Guignard JP (2000) The stressed neonatal kidney: From pathophysiology to clinical management of neonatal vasomotor nephropathy. Pediatr Nephrol 14:227-239 (Pubitemid 30122149)
3. Askenazi DJ, Ambalavanan N, Goldstein SL (2009) Acute kidney injury in critically ill newborns: What do we know? What do we need to learn? Pediatr Nephrol 24:265-274
4. Andreoli SP (2004) Acute renal failure in the newborn. Semin Perinatol 28:112-123 (Pubitemid 38590912)
5. Drukker A, Guignard JP (2002) Renal aspects of the term and preterm infant: A selective update. Curr Opin Pediatr 14:175-182 (Pubitemid 34412161)
6. Gallini F, Maggio L, Romagnoli C, Marrocco G, Tortorolo G (2000) Progression of renal function in preterm neonates with gestational age < or 0 32 weeks, Pediatr Nephrol 15, 119-124
7. Cuzzolin L, Fanos V, Pinna B, di Marzio M, Perin M, Tramontozzi P, Tonetto P, Cataldi L (2006) Postnatal renal function in preterm newborns: A role of diseases, drugs and therapeutic interventions. Pediatr Nephrol 21:931-938 (Pubitemid 43885090)
8. Parikh CR, Lu JC, Coca SG, Devarajan P (2010) Tubular proteinuria in acute kidney injury: A critical evaluation of current status and future promise. Ann Clin Biochem 47:301-312
9. Devarajan P (2008) The future of pediatric acute kidney injury management-biomarkers. Semin Nephrol 28:493-498
10. Bagshaw SM, Bellomo R (2007) Early diagnosis of acute kidney injury. Curr Opin Crit Care 13:638-644 (Pubitemid 350059526)
11. Doi K, Negishi K, Ishizu T, Katagiri D, Fujita T, Matsubara T, Yahagi N, Sugaya T, Noiri E (2011) Evaluation of new acute kidney injury biomarkers in a mixed intensive care unit. Crit Care Med 39:2464-2469
12. Parikh CR, Abraham E, Ancukiewicz M, Edelstein CL (2005) Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit. J Am Soc Nephrol 16:3046-3052 (Pubitemid 44743502)
13. Parikh CR, Jani A, Melnikov VY, Faubel S, Edelstein CL (2004) Urinary interleukin-18 is a marker of human acute tubular necrosis. Am J Kidney Dis 43:405-414 (Pubitemid 38298199)
14. Nejat M, Pickering JW, Walker RJ, Westhuyzen J, Shaw GM, Frampton CM, Endre ZH (2010) Urinary cystatin C is diagnostic of acute kidney injury and sepsis, and predicts mortality in the intensive care unit. Crit Care 14:R85
15. Koyner JL, Bennett MR, Worcester EM, Ma Q, Raman J, Jeevanandam V, Kasza KE, O'Connor MF, Konczal DJ, Trevino S, Devarajan P, Murray PT (2008) Urinary cystatin C as an early biomarker of acute kidney injury following adult cardiothoracic surgery. Kidney Int 74:1059-1069
16. Royakkers AA, Korevaar JC, van Suijlen JD, Hofstra LS, Kuiper MA, Spronk PE, Schultz MJ, Bouman CS (2011) Serum and urine cystatin C are poor biomarkers for acute kidney injury and renal replacement therapy. Intensive Care Med 37:493-501
17. Haase M, Bellomo R, Story D, Davenport P, Haase-Fielitz A (2008) Urinary interleukin-18 does not predict acute kidney injury after adult cardiac surgery: A prospective observational cohort study. Crit Care 12:R96
18. Melnikov VY, Faubel S, Siegmund B, Lucia MS, Ljubanovic D, Edelstein CL (2002) Neutrophil-independent mechanisms of caspase-1-and IL-18-mediated ischemic acute tubular necrosis in mice. J Clin Investig 110:1083-1091 (Pubitemid 35215889)
19. Tschoeke SK, Oberholzer A, Moldawer LL (2006) Interleukin-18: A novel prognostic cytokine in bacteria-induced sepsis. Crit Care Med 34:1225-1233
20. Malyszko J (2010) Biomarkers of acute kidney injury in different clinical settings: A time to change the paradigm? Kidney Blood Press Res 33:368-382
21. Washburn KK, Zappitelli M, Arikan AA, Loftis L, Yalavarthy R, Parikh CR, Edelstein CL, Goldstein SL (2008) Urinary interleukin-18 is an acute kidney injury biomarker in critically ill children. Nephrol Dial Transplant 23:566-572 (Pubitemid 351767629)
22. Finney H, Newman DJ, Thakkar H, Fell JM, Price CP (2000) Reference ranges for plasma cystatin C and creatinine measurements in premature infants, neonates, and older children. Arch Dis Child 82:71-75 (Pubitemid 30305737)
23. Villa P, Jimenez M, Soriano MC, Manzanares J, Casasnovas P (2005) Serum cystatin C concentration as a marker of acute renal dysfunction in critically ill patients. Crit Care 9:R139-R143
24. Conti M, Moutereau S, Zater M, Lallali K, Durrbach A, Manivet P, Eschwege P, Loric S (2006) Urinary cystatin C as a specific marker of tubular dysfunction. Clin Chem Lab Med 44:288-291 (Pubitemid 43357687)
25. Herget-Rosenthal S, van Wijk JA, Brocker-Preuss M, Bokenkamp A (2007) Increased urinary cystatin C reflects structural and functional renal tubular impairment independent of glomerular filtration rate. Clin Biochem 40:946-951 (Pubitemid 47301786)
26. Askenazi DJ, Koralkar R, Levitan EB, Goldstein SL, Devarajan P, Khandrika S, Mehta RL, Ambalavanan N (2011) Baseline values of candidate urine acute kidney injury biomarkers vary by gestational age in premature infants. Pediatr Res 70:302-306
27. Askenazi DJ, Montesanti A, Hunley H, Koralkar R, Pawar P, Shuaib F, Liwo A, Devarajan P, Ambalavanan N (2011) Urine biomarkers predict acute kidney injury and mortality in very low birth weight infants. J Pediatr 159:907-912
28. Dorling JS, Field DJ, Manktelow B (2005) Neonatal disease severity scoring systems. Arch Dis Child Fetal Neonatal Ed 90:F11-F16 (Pubitemid 40040198)
29. Brion LP, Fleischman AR, McCarton C, Schwartz GJ (1986) A simple estimate of glomerular filtration rate in low birth weight infants during the first year of life: Noninvasive assessment of body composition and growth. J Pediatr 109:698-707 (Pubitemid 16028629)
30. Schwartz GJ, Feld LG, Langford DJ (1984) A simple estimate of glomerular filtration rate in full-term infants during the first year of life. J Pediatr 104:849-854 (Pubitemid 14119952)
31. Akcan-Arikan A, Zappitelli M, Loftis LL, Washburn KK, Jefferson LS, Goldstein SL (2007) Modified RIFLE criteria in critically ill children with acute kidney injury. Kidney Int 71:1028-1035 (Pubitemid 46741996)
32. Zappitelli M,Washburn KK, Arikan AA, Loftis L, Ma Q, Devarajan P, Parikh CR, Goldstein SL (2007) Urine neutrophil gelatinaseassociated lipocalin is an early marker of acute kidney injury in critically ill children: A prospective cohort study. Crit Care 11:R84
33. Melnikov VY, Ecder T, Fantuzzi G, Siegmund B, Lucia MS, Dinarello CA, Schrier RW, Edelstein CL (2001) Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure. J Clin Investig 107:1145-1152 (Pubitemid 32422911)
34. Fell JM, Thakkar H, Newman DJ, Price CP (1997) Measurement of albumin and low molecular weight proteins in the urine of newborn infants using a cotton wool ball collection method. Acta Paediatr 86:518-522 (Pubitemid 27244694)
35. Tsukahara H, Hiraoka M, Kuriyama M, Saito M, Morikawa K, Kuroda M, Tominaga T, Sudo M (1993) Urinary alpha 1-microglobulin as an index of proximal tubular function in early infancy. Pediatr Nephrol 7:199-201 (Pubitemid 23093707)
36. Zelenina M, Li Y, Glorieux I, Arnaud C, Cristini C, Decramer S, Aperia A, Casper C (2006) Urinary aquaporin-2 excretion during early human development. Pediatr Nephrol 21:947-952 (Pubitemid 43885092)
37. Tulassay T, Vasarhelyi B (2002) Birth weight and renal function. Curr Opin Nephrol Hypertens 11:347-352 (Pubitemid 34496785)
38. Hellerstein S, Berenbom M, Erwin P, Wilson N, DiMaggio S (2004) The ratio of urinary cystatin C to urinary creatinine for detecting decreased GFR. Pediatr Nephrol 19:521-525 (Pubitemid 38594290)
39. Uchida K, Gotoh A (2002) Measurement of cystatin-C and creatinine in urine. Clin Chim Acta 323:121-128 (Pubitemid 34804801)
40. Kumar D, Super DM, Fajardo RA, Stork EE, Moore JJ, Saker FA (2004) Predicting outcome in neonatal hypoxic respiratory failure with the score for neonatal acute physiology (SNAP) and highest oxygen index (OI) in the first 24 hours of admission. J Perinatol 24:376-381 (Pubitemid 38931093)