Discovery of novel PI3Kγ/δ inhibitors as potential agents for inflammation

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 14, 2012, Pages 4546-4549

  Ellard, Katie ^a   Sunose, Mihiro ^a   Bell, Kathryn ^a   Ramsden, Nigel ^a   Bergamini, Giovanna ^b   Neubauer, Gitte ^b  

^a Cellzome Ltd   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Asthma; Inflammation; PI3K ; Triazolopyridine; Ureas

Indexed keywords

DEXAMETHASONE; PHOSPHATIDYLINOSITOL 3 KINASE ALPHA INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; DRUG EFFICACY; DRUG SELECTIVITY; MOUSE; NONHUMAN; PNEUMONIA; REVIEW;

EID: 84863443954     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.05.121     Document Type: Article

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