New farnesyltransferase inhibitors in the phenothiazine series

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 14, 2012, Pages 4517-4522

  Belei, Dalila ^a   Dumea, Carmen ^a   Samson, Alexandrina ^a   Farce, Amaury ^b,c   Dubois, Joëlle ^d   Bîcu, Elena ^a   Ghinet, Alina ^a,b,e  

^a ALEXANDRU IOAN CUZA UNIVERSITY OF IASI   (Romania)

^b UNIV LILLE   (France)

^c Faculté des Sciences Pharmaceutiques et Biologiques Université de Lille   (France)

^d INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

^e UNIVERSITÉ CATHOLIQUE DE LILLE   (France)

Author keywords

Anticancer agent; Farnesyltransferase inhibitor; Phenothiazine; Triazole

Indexed keywords

1,2,3 TRIAZOLE DERIVATIVE; ANTINEOPLASTIC AGENT; PHENOTHIAZINE DERIVATIVE; PROTEIN FARNESYLTRANSFERASE INHIBITOR;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; FLUORESCENCE; HUMAN; HUMAN TISSUE;

CELL LINE, TUMOR; CELL SURVIVAL; FARNESYLTRANSTRANSFERASE; HUMANS; MOLECULAR STRUCTURE; PHENOTHIAZINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84863429998     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.06.007     Document Type: Article

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