Estrogenic activity of B-fluorinated o-carborane-1,2-bisphenol synthesized via SNAr reaction

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 14, 2012, Pages 4728-4730

  Ohta, Kiminori ^a   Ogawa, Takumi ^a   Endo, Yasuyuki ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Carboranes; Estrogen; Estrogen receptors; SERMs

Indexed keywords

1,2 BIS(4 HYDROXYPHENYL) O CARBORANE BISPHENOL; BE 310; BE 360; CARBORANE DERIVATIVE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; SELECTIVE ESTROGEN RECEPTOR MODULATOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ESTROGEN ACTIVITY; FLUORINATION; IC 50; SUBSTITUTION REACTION;

ANIMALS; BORON COMPOUNDS; CELL PROLIFERATION; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; HUMANS; MCF-7 CELLS; MICE; MOLECULAR STRUCTURE; PHENOLS; STRUCTURE-ACTIVITY RELATIONSHIP;

MUS;

EID: 84863423840     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.05.068     Document Type: Article

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