Massive Transfusion of Blood in the Surgical Patient

Surgical Clinics of North America

Volumn 92, Issue 2, 2012, Pages 221-234

  Raymer, Jordan M ^a   Flynn, Lisa M ^b   Martin, Ronald F ^a,c  

^a Saint Joseph's Hospital Wisconsin   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Blood products; Blood transfusion; Transfusion related injury; Trauma

Indexed keywords

FRESH FROZEN PLASMA; RECOMBINANT BLOOD CLOTTING FACTOR 7A;

ACIDEMIA; BACTERIUM CONTAMINATION; BLEEDING; BLOOD CLOTTING DISORDER; BLOOD COMPATIBILITY; BLOOD COMPONENT THERAPY; BLOOD EXAMINATION; BLOOD PH; BLOOD STORAGE; BLOOD TRANSFUSION; BODY TEMPERATURE; CAUSE OF DEATH; CRYOPRESERVATION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ERYTHROCYTE CONCENTRATE; ERYTHROCYTE TRANSFUSION; HEMOPHILIA; HISTORY; HUMAN; HYPOTHERMIA; HYPOVOLEMIC SHOCK; NONHUMAN; PALLIATIVE THERAPY; PRACTICE GUIDELINE; PRIORITY JOURNAL; REVIEW; SURGICAL PATIENT; TRANSFUSION RELATED ACUTE LUNG INJURY;

BLOOD PRESERVATION; BLOOD TRANSFUSION; HEMORRHAGE; HUMANS; INTRAOPERATIVE CARE; WAR; WOUNDS AND INJURIES;

EID: 84863417115     PISSN: 00396109     EISSN: 15583171     Source Type: Journal    
DOI: 10.1016/j.suc.2012.01.008     Document Type: Review

References (63)

1. Kauvar D., Lefering R., Wade C. Impact of hemorrhage on trauma outcome: an overview of epidemiology, clinical presentation, and therapeutic considerations. J Trauma 2006, 60:S3-S11.
2. Mitra B., Cameron P., Gruen R.L., et al. The definition of massive transfusion in trauma: a critical variable in examining evidence for resuscitation. Eur J Emerg Med 2011, 18:137-142.
3. Sihler K.C., Napolitano L.M. Massive transfusion. Chest 2009, 136:1654-1667.
4. Spinella P. Warm fresh whole blood transfusion for severe hemorrhage: U.S. military and potential civilian applications. Crit Care Med 2008, 36:S340-S345.
5. Hoyt D. Blood and war-lest we forget. J Am Coll Surg 2009, 209:681-686.
6. Hess J.R., Zimrin A.B. Massive blood transfusion for trauma. Curr Opin Hematol 2005, 12:488-492.
7. Cannon J., Fischer J.E., Edward D. Churchill as a combat consultant. Ann Surg 2010, 251:566-572.
8. Hustin A. Principe d'une nouvelle method de transfusion. Journal Medical de Bruxelles 1914, 2:436.
9. Lewisohn R. Blood transfusion by citrate method. Surg Gynecol Obstet 1915, 21:37-47.
10. Weil R. Sodium citrate in the transfusion of blood. JAMA 1915, 64(5):425-426.
11. Rous P., Turner J. The transfusion of kept cells. J Exp Med 1916, 23:239-247.
12. Hess J.R., Brohi K., Dutton R.P., et al. The coagulopathy of trauma: a review of mechanisms. J Trauma 2008, 65:748-754.
13. Zimrin A.B., Hess J.R. Current issues relating to the transfusion of stored red blood cells. Vox Sang 2009, 96:93-103.
14. Gilliss B., Looney M. Reducing noninfectious risk of blood transfusion. Anesthesiology 2011, 115:635-649.
15. Stoll C., Wolkers W. Membrane stability during biopreservation of blood. Transfus Med Hemother 2011, 38:89-97.
16. Lelubre C., Piagnerelli M., Vincent J.L. Association between duration of storage of transfused red blood cells and morbidity and mortality in adult patients: myth or reality?. Transfusion 2009, 49:1384-1389.
17. Hassan M., Pham T., Cuschieri J., et al. The association between the transfusion of older blood and outcomes after trauma. Shock 2011, 35:3-8.
18. Zallen G., Offner P., Moore E., et al. Age of transfused blood is an independent risk factor for postinjury multiple organ failure. Am J Surg 1999, 178:570-572.
19. Offner P., Moore E., Biffl W., et al. Increased rate of infection associated with transfusion of old blood after severe injury. Arch Surg 2002, 137:711-717.
20. Malone D., Dunne J., Tracy K., et al. Blood transfusion, independent of shock severity, is associated with worse outcome in trauma. J Trauma 2003, 54:898-907.
21. Alter H., Klein H. The hazards of blood transfusion in a historical perspective. Blood 2008, 112:2617-2626.
22. Blumberg N., Bove J. Uncrossmatched blood for emergency transfusion. JAMA 1978, 240:2057-2059.
23. Dutton R., Shih D., Edelman B., et al. Safety of uncrossmatched type-O red cells for resuscitation from hemorrhagic shock. J Trauma 2005, 59:1445-1449.
24. Schwab C. Immediate trauma resuscitation with type O uncrossmatched blood: a two-year prospective experience. J Trauma 1986, 26:897-902.
25. Inaba K., Pedro G.R., Shulman I., et al. The impact of uncross-matched blood transfusion on the need for massive transfusion and mortality: analysis of 5166 uncross-matched units. J Trauma 2008, 65:1222-1226.
26. Sebesta M.A. Special lessons learned from Iraq. Surg Clin North Am 2006, 86:711-726.
27. Tsuei B., Kearney P. Hypothermia in the trauma patient. Injury 2004, 35:7-15.
28. Jurkovich G., Greiser W. Hypothermia in trauma victims: an ominous predictor of survival. J Trauma 1987, 27:1019-1024.
29. Sihler K.C., Napolitano L.M. Complications of massive transfusion. Chest 2010, 137:209-220.
30. Johansson P., Ostrowsk R., Secher N. Management of major blood loss: an update. Acta Anaesthesiol Scand 2010, 54:1039-1049.
31. Meng Z., Wolberg A., Monroe D. The effect of temperature and pH on the activity of factor VIIa: implications for the efficacy of high dose factor VIIa in hypothermic and acidotic patients. J Trauma 2003, 55:886-891.
32. Davis J., Parks S., Kaups K., et al. Admission base deficits predicts transfusion requirement and risks of complications. J Trauma 1996, 41:769-774.
33. Thorsen K., Ringdal K.G., Soreide E., et al. Clinical and cellular effects of hypothermia, acidosis and coagulopathy in major injury. Br J Surg 2011, 98:894-907.
34. Repine T.B., Perkins J.G., Kauvar D.S., et al. The use of fresh whole blood in massive transfusion. J Trauma 2006, 60:S59-S69.
35. Spinella P., Perkins J., Grathwohl K., et al. Warm fresh blood is independently associated with improved survival for patients with combat-related traumatic injuries. J Trauma 2009, 66:S69-S76.
36. Spinella P., Perkins J., Grathwohl K., et al. Risks associated with fresh whole blood transfusions in a combat support hospital. Crit Care Med 2007, 35:2576-2581.
37. Linden J., Davey R., Burch J., et al. The September 11th, 2001 disaster and the New York blood supply. Transfusion 2002, 42:1385-1387.
38. Spahn D.R., Rossaint R. Coagulopathy and blood component transfusion in trauma. Br J Anaesth 2005, 95:130-139.
39. Jansen J., Thomas R., Louson M., et al. Damage control resuscitation for patients with major trauma. BMJ 2009, 338:1436-1440.
40. Mitra B., Mori A., Cameron P.A., et al. Fresh frozen plasma use during massive blood transfusion in trauma resuscitation. Injury 2010, 41:35-39. Int J Care Injured.
41. Zink K.A., Sambasivan C.N., Holcomb J.B., et al. A high ratio of plasma and platelets to packed red blood cells in the first 6 hours of massive transfusion improves outcomes in a large multicenter study. Am J Surg 2009, 197:565-570.
42. Borgman M.A., Spinella P.C., Perkins J.G., et al. The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital. J Trauma 2007, 63:805-813.
43. Johansson P., Stensalle J. Hemostatic resuscitation for massive bleeding: the paradigm of plasma and platelets-a review of the current literature. Transfusion 2010, 50:701-710.
44. Duschesne J.C., Hunt J.P., Wahl G., et al. Review of the current blood transfusions strategies in a mature level I trauma center: were we wrong for the last 60 years?. J Trauma 2008, 65:272-276.
45. Davenport R., Curry N., Manson J., et al. Hemostatic effects of fresh frozen plasma may be maximal at red cell ratios of 1:2. J Trauma 2011, 70:90-96.
46. Holcomb J.B., Wade C.E., Michalek C.E., et al. Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients. Ann Surg 2008, 248:447-458.
47. Sperry J.L., Ochoa J.B., Gunn S.R., et al. An FFP:PRBC transfusion ratio >1:1.5 is associated with a lower risk of mortality after massive transfusion. J Trauma 2008, 65:986-993.
48. Toy P., Popovsky M., Abraham E., et al. Transfusion related acute lung injury: definition and review. Crit Care Med 2005, 33:721-726.
49. Sheppard C., Lodgberg L., Zimring J., et al. Transfusion related acute lung injury. Hematol Oncol Clin North Am 2007, 21:163-176.
50. Kleinman S., Caulfield T., Chan P., et al. Toward an understanding of transfusion related acute lung injury: statement of a consensus panel. Transfusion 2004, 44:1774-1789.
51. Silliman C., Boshkov L., Mehdizadehkashi Z., et al. Transfusion related acute lung injury: epidemiology and prospective analysis of etiologic factors. Blood 2003, 101:454-462.
52. Looney M., Gillis B., Matthay M. Pathophysiology of transfusion-related acute lung injury. Curr Opin Hematol 2010, 17:418-423.
53. Hess J.R. Translating research in the intensive care unit into effective educational strategies. Crit Care Med 2010, 38:981-982.
54. Cherry T., Steciuk M., Reddy V., et al. Transfusion related acute lung injury: past and present. Am J Clin Pathol 2008, 129:287-297.
55. Mitra B., Cameron P., Phillips L. Recombinant factor VIIa in trauma patients with the triad of death. Injury 2011, 1:1-6.
56. Gonzalez E, Jastrow K, Holcomb J, et al. Schwartz's principles of surgery. 9th edition. Available at: Accessed January 9, 2012. http://www.accesssurgery.com.
57. Boffard K., Riou B., Warren B., et al. Recombinant factor VIIa as adjunctive therapy for bleeding in severely injured trauma patients: two parallel randomized, placebo-controlled, double-blind clinical trials. J Trauma 2005, 59:8-18.
58. Dutton R., Hauser C., Boffard K., et al. Scientific and logistical challenges in designing the CONTROL trial: recombinant factor VIIa in severe trauma patients with refractory bleeding. Clin Trials 2009, 6:467-479.
59. Rizoli S., Boffard K., Riou B., et al. Recombinant activated factor VII as an adjunctive therapy for bleeding control in severe trauma patients with coagulopathy: subgroup analysis from two randomized trials. Crit Care 2006, 10:R178.
60. Meng Z., Wolberg A., Monroe D., et al. The effect of temperature and pH on factor VIIa: implications for the efficacy of high dose factor VIIa in hypothermic and acidotic patients. J Trauma 2003, 55:855-861.
61. Yucel N., Lefering R., Maegele M., et al. Trauma associated severe hemorrhage (TASH)-score: probability of mass transfusion as surrogate for life threatening hemorrhage after multiple trauma. J Trauma 2006, 60:1228-1237.
62. Nunez T., Vosckrensensky I., Dossett L., et al. Early prediction of massive transfusion in trauma: simple as ABC (assessment of blood consumption)?. J Trauma 2009, 66:346-352.
63. Spinella P., Perkins J., McLaughlin D., et al. The effect of recombinant activated factor VII on mortality in combat-related casualties with severe trauma and massive transfusion. J Trauma 2008, 64:286-294.