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Volumn 20, Issue 9, 2012, Pages 3009-3015
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Synthesis and biological evaluation of a series of thieno-expanded tricyclic purine 2′-deoxy nucleoside analogues
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Author keywords
Adenosine; Expanded purine; Guanosine; Nucleobase; Nucleosides; Tricyclic
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Indexed keywords
1 (2' DEOXY BETA DEXTRO RIBOFURANOSE 1 YL) 4,5 DIIODOIMIDAZOLE;
1 [(5 AMINOIMIDAZO[4',5':4,5]THIENO[3,2 D]PYRIMIDIN 3 YL 7 ONE)] 2,3,5 BETA DEXTRO DEOXYRIBOFURANOSE;
1 [(5 AMINOIMIDAZO[4',5':4,5]THIENO[3,2 D]PYRIMIDIN 3 YL 7 ONE)]BETA DEXTRO 2' DEOXYRIBOFURANOSE;
1 [(7 AMINOIMIDAZO)[4',5':4,5]THIENO[3,2 D]PYRIMIDIN 3 YL]BETA DEXTRO 2' DEOXYRIBOFURANOSE;
1 [2' DEOXY 3',5' DI O (4 TOLUOYL)BETA DEXTRO RIBOFURANOSE 1 YL] 4,5 DIIODOIMIDAZOLE;
2' DEOXYNUCLEOSIDE;
3' (4 METHOXYBENZLYOXY) 5' (4 METHOXYBENZYLOXYMETHYL) 1 (4,5 DIIODOIMIDAZOL 3 YL)BETA DEXTRO 2' DEOXYRIBOFURANOSE;
3' (4 METHOXYBENZLYOXY) 5' (4 METHOXYBENZYLOXYMETHYL) 1 (IMIDAZO[4',5V:4,5]THIENO[3,2 D]PYRIMIDIN 3 YL)BETA DEXTRO 2' DEOXYRIBOFURANOSE;
3' (4 METHOXYBENZLYOXY) 5' (4 METHOXYBENZYLOXYMETHYL) 1 [(5 AMINOIMIDAZO)[4',5':4,5]THIENO[2,3 D]PYRIMIDIN 3 YL]BETA DEXTRO 2' DEOXYRIBOFURANOSE;
3' (4 METHOXYBENZLYOXY) 5' (4 METHOXYBENZYLOXYMETHYL) 1 [(5 CARBOXAMIDE)[2,3 D]IMIDAZOL 3 YL]BETA DEXTRO 2' DEOXYRIBOFURANOSE;
3' (4 METHOXYBENZLYOXY) 5' (4 METHOXYBENZYLOXYMETHYL) 1 [(5 IODO 4 CARBALDEHYDE)IMIDAZOL 3 YL]BETA DEXTRO 2' DEOXYRIBOFURANOSE;
3' (4 METHOXYBENZLYOXY) 5' (4 METHOXYBENZYLOXYMETHYL) 1 [(5 IODO 4 CARBALDEHYDEOXIME)IMIDAZOL 3 YL]BETA DEXTRO 2' DEOXYRIBOFURANOSE;
3' (4 METHOXYBENZLYOXY) 5' (4 METHOXYBENZYLOXYMETHYL) 1 [(5 IODO 4 CARBONITRILE)IMIDAZOL 3 YL]BETA DEXTRO 2' DEOXYRIBOFURANOSE;
3' (4 METHOXYBENZLYOXY) 5' (4 METHOXYBENZYLOXYMETHYL) 1 [(7 AMINOIMIDAZO[4',5':4,5]THIENO[3,2 D]PYRIMIDIN 3 YL)]BETA DEXTRO 2' DEOXYRIBOFURANOSE;
3',5' (1,1,3,3 TETRAISOPROPYLDISILOXANE 1,3 DIYL) [N7 ISOBUTYRYL 7 AMINOIMIDAZO[4',5'.4,5]THIENO[3,2 D]PYRIMIDIN 3 YL 7 ONE] 2,3,5 BETA DEXTRO DEOXYRIBOFURANOSE;
3',5' (1,1,3,3 TETRAISOPROPYLDISILOXANE 1,3 DIYL) [N7 ISOBUTYRYL 7 AMINOIMIDAZO[4',5'.4,5]THIENO[3,2 D]PYRIMIDIN 3 YL 7 ONE] 2,3,5 BETA DEXTRO RIBOFURANOSE;
3',5' (1,1,3,3 TETRAISOPROPYLDISILOXANE 1,3 DIYL) [N7 ISOBUTYRYL 7 AMINOIMIDAZO[4',5'.4,5]THIENO[3,2 D]PYRIMIDIN 3 YL 7 ONE] 2,3,5 BETA DEXTRO RIBOFURANOSE 2' O THIOCARBONATE PHENYL ESTER;
ADENOSINE DERIVATIVE;
ANTINEOPLASTIC AGENT;
DEOXYGUANOSINE DERIVATIVE;
IMIDAZOLE;
PURINE;
PYRIMIDINE;
SCAFFOLD PROTEIN;
THIOPHENE DERIVATIVE;
TRICYCLIC PURINE 2' DEOXYNUCLEOSIDE DERIVATIVE;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ANTIVIRAL ACTIVITY;
ARTICLE;
CANCER INHIBITION;
CELL PROLIFERATION;
COMPLEX FORMATION;
CONTROLLED STUDY;
CYTOSTASIS;
DRUG DESIGN;
DRUG SCREENING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
LUNG FIBROBLAST;
NONHUMAN;
STRUCTURE ACTIVITY RELATION;
STRUCTURE ANALYSIS;
ANTINEOPLASTIC AGENTS;
ANTIVIRAL AGENTS;
CELL LINE, TUMOR;
CELL PROLIFERATION;
DRUG DESIGN;
GUANOSINE;
HELA CELLS;
HUMANS;
IMIDAZOLES;
PURINE NUCLEOSIDES;
PYRIMIDINES;
THIOPHENES;
VIRUS REPLICATION;
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EID: 84863406153
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2012.03.004 Document Type: Article |
Times cited : (23)
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References (40)
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