Selective transport of a new class of purine antimetabolites by the protozoan parasite Trypanosoma brucei

Nucleosides, Nucleotides and Nucleic Acids

Volumn 23, Issue 8-9, 2004, Pages 1441-1444

  Wallace, L J M ^a   Candlish, D ^a   Hagos, A ^b   Seley, K L ^b,c   De Koning, H P ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

Author keywords

Drug selectivity; Drug uptake; Purine antimetabolite; Purine transporter; Trypanosoma brucei

Indexed keywords

ADENINE DERIVATIVE; ANTIMETABOLITE; GUANINE DERIVATIVE; HYPOXANTHINE DERIVATIVE; TRI B 001; TRI B 002; TRI B 003; UNCLASSIFIED DRUG;

CANCER; COMPETITIVE INHIBITION; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACCUMULATION; DRUG SELECTIVITY; DRUG TARGETING; DRUG TRANSPORT; DRUG UPTAKE; ERYTHROCYTE; HUMAN; HUMAN CELL; IN VITRO STUDY; INFECTION; NONHUMAN; TARGET CELL; TRYPANOSOMA BRUCEI;

ALLOPURINOL; ANIMALS; ANTIMETABOLITES; BIOLOGICAL TRANSPORT; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; HUMANS; KINETICS; MODELS, CHEMICAL; NUCLEOBASE TRANSPORT PROTEINS; OXAZINES; PURINES; RATS; TRYPANOSOMA BRUCEI BRUCEI; XANTHENES;

PROTOZOA; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

EID: 10344242019     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-200027660     Document Type: Conference Paper

References (8)

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