Carbocyclic pyrimidine nucleosides as inhibitors of S-adenosylhomocysteine hydrolase

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 23, 2006, Pages 7967-7971

  Mosley, Sylvester L ^a   Bakke, Brian A ^a   Sadler, Joshua M ^a   Sunkara, Naresh K ^a   Dorgan, Kathleen M ^b   Zhou, Zhaohui Sunny ^b   Seley Radtke, Katherine L ^a  

^a UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

^b WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Carbocyclic; MTAN; Nucleoside; Pyrimidine; SAHase

Indexed keywords

1 [(2',3' (O ISOPROPYLIDENE)CYCLOPENT 1' YL]URACIL; 1 [(2',3' DIHYDROXY) 40 CYCLOPENTEN 1' YL]CYTOSINE; 1 [(2',3' DIHYDROXY)CYCLOPENT 1' YL]CYTOSINE; 1 [(2',3' DIHYDROXY)CYCLOPENT 1' YL]URACIL; 1 [(2',3' O ISOPROPYLIDENE) 40 CYCLOPENTEN 1' YL]CYTOSINE; 1 [(2',3' O ISOPROPYLIDENE) CYCLOPENTEN 1' YL]CYTOSINE; ADENOSYLHOMOCYSTEINASE; ADENOSYLHOMOCYSTEINASE INHIBITOR; PYRIMIDINE NUCLEOSIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DRUG ACTIVITY; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION;

ADENOSYLHOMOCYSTEINASE; DRUG DESIGN; KINETICS; PYRIMIDINE NUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33750061640     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.07.052     Document Type: Article

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