Synthesis and antitumor activity of thieno-separated tricyclic purines

Journal of Medicinal Chemistry

Volumn 43, Issue 25, 2000, Pages 4877-4883

  Seley, K L ^a   Januszczyk, P ^a   Hagos, A ^a   Zhang, L ^a   Dransfield, D T ^b  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOIMIDAZO[4',5':4,5]THIENO[3,2]PYRIMIDIN 5(6H)ONE; 6 AMINOIMIDAZO[4',5':4,5]THIENO[3,2]PYRIMIDINE; PURINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING SITE; CANCER CELL; COLORECTAL CANCER; CONTROLLED STUDY; DNA DAMAGE; DRUG ACTIVITY; DRUG BINDING; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME BINDING; ENZYME SUBSTRATE COMPLEX; HUMAN; HUMAN CELL; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL DIVISION; COLORECTAL NEOPLASMS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; PURINES; PYRIMIDINES; PYRIMIDINONES; THIOPHENES; TUMOR CELLS, CULTURED;

EID: 0034649653     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000326i     Document Type: Article

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