The 5-lipoxygenase pathway is required for acute lung injury following hemorrhagic shock

Shock

Volumn 37, Issue 6, 2012, Pages 599-604

  Eun, John C ^a   Moore, Ernest E ^a,b   Mauchley, David C ^a   Johnson, Chris A ^c   Meng, Xianzhong ^a   Banerjee, Anirban ^a   Wohlauer, Max V ^a   Zarini, Simona ^c   Gijón, Miguel A ^c   Murphy, Robert C ^c  

^a UNIVERSITY OF COLORADO   (United States)

^b DENVER HEALTH MEDICAL CENTER   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

eicosanoids; inflammation; leukotrienes; mass spectrometry; Multiple organ failure; pharmacological inhibition; transgenic mice

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ARACHIDONATE 5 LIPOXYGENASE; LEUKOTRIENE B4; LEUKOTRIENE C4;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; CONTROLLED STUDY; DISEASE MODEL; EXTRAVASATION; HEMORRHAGIC SHOCK; IMMUNOFLUORESCENCE; LIQUID CHROMATOGRAPHY; LUNG LAVAGE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; SHAM PROCEDURE; TANDEM MASS SPECTROMETRY; TRANSGENIC MOUSE;

ACUTE LUNG INJURY; ANIMALS; ARACHIDONATE 5-LIPOXYGENASE; BRONCHOALVEOLAR LAVAGE FLUID; DINOPROSTONE; EICOSANOIDS; INDOLES; LEUKOTRIENE B4; LEUKOTRIENE C4; LIPOXYGENASE INHIBITORS; LUNG; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEUTROPHILS; PEROXIDASE; SHOCK, HEMORRHAGIC;

EID: 84863397406     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e31824ee7bc     Document Type: Article

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