메뉴 건너뛰기




Volumn 279, Issue 1732, 2012, Pages 1389-1395

Effects of BRCA1 and BRCA2 mutations on female fertility

Author keywords

BRCA1; BRCA2; Fertility; Mortality; Pleiotropy; Telomeres

Indexed keywords

CANCER; FERTILITY; FITNESS; MORALITY; MUTATION; PLEIOTROPY;

EID: 84863393398     PISSN: 09628452     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rspb.2011.1697     Document Type: Article
Times cited : (89)

References (34)
  • 2
    • 0028843102 scopus 로고
    • Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium
    • Easton, D. F., Ford, D. & Bishop, D. T. 1995 Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium. Am. J. Hum. Genet. 56, 265-271.
    • (1995) Am. J. Hum. Genet , vol.56 , pp. 265-271
    • Easton, D.F.1    Ford, D.2    Bishop, D.T.3
  • 3
    • 33746476567 scopus 로고    scopus 로고
    • Spontaneous and therapeutic abortions and the risk of breast cancer among BRCA mutation carriers
    • (doi:10.1186/bcr1387)
    • Friedman, E. et al. 2006 Spontaneous and therapeutic abortions and the risk of breast cancer among BRCA mutation carriers. Breast Cancer Res. 8, R15. (doi:10.1186/bcr1387)
    • (2006) Breast Cancer Res , vol.8
    • Friedman, E.1
  • 4
    • 77249112200 scopus 로고    scopus 로고
    • Impact of BRCA mutations on female fertility and offspring sex ratio
    • Moslehi, R., Singh, R., Lessner, L. & Friedman, J. M. 2010 Impact of BRCA mutations on female fertility and offspring sex ratio. Am. J. Hum. Biol. 22, 201-205.
    • (2010) Am. J. Hum. Biol , vol.22 , pp. 201-205
    • Moslehi, R.1    Singh, R.2    Lessner, L.3    Friedman, J.M.4
  • 5
    • 62849118739 scopus 로고    scopus 로고
    • Potential excess mortality in BRCA1/2 mutation carriers beyond breast, ovarian, prostate, and pancreatic cancers, and melanoma
    • (doi:10.1371/journal.pone.0004812)
    • Mai, P. L., Chatterjee, N., Hartge, P., Tucker, M., Brody, L., Struewing, J. P., Wacholder, S. & Toland, A. E. 2009 Potential excess mortality in BRCA1/2 mutation carriers beyond breast, ovarian, prostate, and pancreatic cancers, and melanoma. PLoS ONE 4, e4812. (doi:10.1371/journal.pone.0004812)
    • (2009) PLoS ONE , vol.4
    • Mai, P.L.1    Chatterjee, N.2    Hartge, P.3    Tucker, M.4    Brody, L.5    Struewing, J.P.6    Wacholder, S.7    Toland, A.E.8
  • 6
    • 0000055057 scopus 로고
    • Pleiotropy, natural selection, and the evolution of senescence
    • (doi:10.2307/2406060)
    • Williams, G. C. 1957 Pleiotropy, natural selection, and the evolution of senescence. Evolution 11, 398-411. (doi:10.2307/2406060)
    • (1957) Evolution , vol.11 , pp. 398-411
    • Williams, G.C.1
  • 7
    • 43149121837 scopus 로고    scopus 로고
    • Negative selection on BRCA1 susceptibility alleles sheds light on the population genetics of late-onset diseases and aging theory
    • (doi:10.1371/journal.pone.0001206)
    • Pavard, S. & Metcalf, C. J. 2007 Negative selection on BRCA1 susceptibility alleles sheds light on the population genetics of late-onset diseases and aging theory. PLoSONE 2, e1206. (doi:10.1371/journal.pone.0001206)
    • (2007) PLoSONE , vol.2
    • Pavard, S.1    Metcalf, C.J.2
  • 8
    • 3543038163 scopus 로고    scopus 로고
    • Decision making with uncertain information: Learning from women in a high risk breast cancer clinic
    • (doi:10.1023/B:JOGC.0000027958.02383.a9)
    • Frost, C., Venne, V., Cunningham, D. & Gerritsen-McKane, R. 2004 Decision making with uncertain information: learning from women in a high risk breast cancer clinic. J. Genet. Couns. 13, 221. (doi:10.1023/B:JOGC.0000027958.02383.a9)
    • (2004) J. Genet. Couns , vol.13 , pp. 221
    • Frost, C.1    Venne, V.2    Cunningham, D.3    Gerritsen-McKane, R.4
  • 9
    • 7044272596 scopus 로고    scopus 로고
    • The Breast Cancer Family Registry: An infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancer
    • (doi:10.1186/bcr801)
    • John, E. M. et al. 2004 The Breast Cancer Family Registry: an infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancer. Breast Cancer Res. 6, R375-R389. (doi:10.1186/bcr801)
    • (2004) Breast Cancer Res , vol.6
    • John, E.M.1
  • 10
    • 0037087536 scopus 로고    scopus 로고
    • Clinical characteristics of individuals with germline mutations in BRCA1 and BRCA2: Analysis of 10,000 individuals
    • (doi:10.1200/JCO.20.6.1480)
    • Frank, T. S. et al. 2002 Clinical characteristics of individuals with germline mutations in BRCA1 and BRCA2: analysis of 10,000 individuals. J. Clin. Oncol. 20, 1480-1490. (doi:10.1200/JCO.20.6.1480)
    • (2002) J. Clin. Oncol , vol.20 , pp. 1480-1490
    • Frank, T.S.1
  • 12
    • 0037334489 scopus 로고    scopus 로고
    • Biomedical databases: Protecting privacy and promoting research
    • (doi:10.1016/S0167-7799(02) 00039-2)
    • Wylie, J. E. & Mineau, G. P. 2003 Biomedical databases: protecting privacy and promoting research. Trends Biotechnol. 21, 113-116. (doi:10.1016/S0167-7799(02) 00039-2)
    • (2003) Trends Biotechnol , vol.21 , pp. 113-116
    • Wylie, J.E.1    Mineau, G.P.2
  • 13
    • 35748929114 scopus 로고    scopus 로고
    • Founder mutations in BRCA1 and BRCA2 genes
    • (doi:10.1093/annonc/mdm234)
    • Ferla, R. et al. 2007 Founder mutations in BRCA1 and BRCA2 genes. Ann. Oncol. 18(Suppl. 6), vi93-vi98. (doi:10.1093/annonc/mdm234)
    • (2007) Ann. Oncol , vol.18 , Issue.SUPPL. 6
    • Ferla, R.1
  • 14
    • 19144362921 scopus 로고    scopus 로고
    • Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: Results of an international study
    • Neuhausen, S. L. et al. 1996 Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study. Am. J. Hum. Genet. 58, 271-280.
    • (1996) Am. J. Hum. Genet , vol.58 , pp. 271-280
    • Neuhausen, S.L.1
  • 15
    • 24944474798 scopus 로고    scopus 로고
    • Upregulation of the BRCA1 gene in human germ cells and in preimplantation embryos
    • (doi:10.1016/j.fertnstert.2005.02.037)
    • Giscard d'Estaing, S., Perrin, D., Lenoir, G. M., Guerin, J. F. & Dante, R. 2005 Upregulation of the BRCA1 gene in human germ cells and in preimplantation embryos. Fertil. Steril. 84, 785-788. (doi:10.1016/j.fertnstert.2005.02.037)
    • (2005) Fertil. Steril , vol.84 , pp. 785-788
    • Giscard d'Estaing, S.1    Perrin, D.2    Lenoir, G.M.3    Guerin, J.F.4    Dante, R.5
  • 16
    • 0029784528 scopus 로고    scopus 로고
    • Inactivation of themouse BRCA1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development
    • (doi:10.1101/gad.10.14.1835)
    • Liu, C. Y., Flesken-Nikitin, A., Li, S., Zeng, Y.& Lee, W.H. 1996 Inactivation of themouse BRCA1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development. Genes Dev. 10, 1835-1843. (doi:10.1101/gad.10.14.1835)
    • (1996) Genes Dev , vol.10 , pp. 1835-1843
    • Liu, C.Y.1    Flesken-Nikitin, A.2    Li, S.3    Zeng, Y.4    Lee, W.H.5
  • 17
    • 0034707053 scopus 로고    scopus 로고
    • In search of the tumour-suppressor functions of BRCA1 and BRCA2
    • (doi:10.1038/35044000)
    • Scully, R. & Livingston, D. M. 2000 In search of the tumour-suppressor functions of BRCA1 and BRCA2. Nature 408, 429-432. (doi:10.1038/35044000)
    • (2000) Nature , vol.408 , pp. 429-432
    • Scully, R.1    Livingston, D.M.2
  • 18
    • 0043198132 scopus 로고    scopus 로고
    • Association between BRCA1 mutations and ratio of female to male births in offspring of families with breast cancer, ovarian cancer, or both
    • (doi:10.1001/jama.290.7.929)
    • de la Hoya, M., Fernandez, J. M., Tosar, A., Godino, J., Sanchez de Abajo, A., Vidart, J. A., Pérez-Segura, P. & Díaz-Rubio, E. 2003 Association between BRCA1 mutations and ratio of female to male births in offspring of families with breast cancer, ovarian cancer, or both. JAMA 290, 929-931. (doi:10.1001/jama.290.7.929)
    • (2003) JAMA , vol.290 , pp. 929-931
    • de la Hoya, M.1    Fernandez, J.M.2    Tosar, A.3    Godino, J.4    de Abajo, A.S.5    Vidart, J.A.6    Pérez-Segura, P.7    Díaz-Rubio, E.8
  • 19
    • 77949916951 scopus 로고    scopus 로고
    • Fertility in women with BRCA mutations: A case-control study
    • (doi:10.1016/j.fertnstert.2008.12.052)
    • Pal, T., Keefe, D., Sun, P. & Narod, S. A. 2010 Fertility in women with BRCA mutations: a case-control study. Fertil. Steril. 93, 1805-1808. (doi:10.1016/j.fertnstert.2008.12.052)
    • (2010) Fertil. Steril , vol.93 , pp. 1805-1808
    • Pal, T.1    Keefe, D.2    Sun, P.3    Narod, S.A.4
  • 20
    • 32544442886 scopus 로고    scopus 로고
    • Disruption of BRCA1 function results in telomere lengthening and increased anaphase bridge formation in immortalized cell lines
    • (doi:10.1002/gcc.20290)
    • French, J. D., Dunn, J., Smart, C. E., Manning, N. & Brown, M. A. 2006 Disruption of BRCA1 function results in telomere lengthening and increased anaphase bridge formation in immortalized cell lines. Genes Chromosomes Cancer 45, 277-289. (doi:10.1002/gcc.20290)
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 277-289
    • French, J.D.1    Dunn, J.2    Smart, C.E.3    Manning, N.4    Brown, M.A.5
  • 21
    • 0242721645 scopus 로고    scopus 로고
    • BRCA1 inhibition of telomerase activity in cultured cells
    • (doi:10.1128/MCB.23.23.8668-8690.2003)
    • Xiong, J. et al. 2003 BRCA1 inhibition of telomerase activity in cultured cells. Mol. Cell Biol. 23, 8668-8690. (doi:10.1128/MCB.23.23.8668-8690.2003)
    • (2003) Mol. Cell Biol , vol.23 , pp. 8668-8690
    • Xiong, J.1
  • 22
    • 73649113140 scopus 로고    scopus 로고
    • BRCA1 localization to the telomere and its loss from the telomere in response to DNA damage
    • (doi:10.1074/jbc.M109.025825)
    • Ballal, R. D., Saha, T., Fan, S., Haddad, B. R. & Rosen, E. M. 2009 BRCA1 localization to the telomere and its loss from the telomere in response to DNA damage. J. Biol. Chem. 284, 36 083-36 098. (doi:10.1074/jbc.M109.025825)
    • (2009) J. Biol. Chem , vol.284 , pp. 36083-36098
    • Ballal, R.D.1    Saha, T.2    Fan, S.3    Haddad, B.R.4    Rosen, E.M.5
  • 23
    • 33644750447 scopus 로고    scopus 로고
    • A role for Brca1 in chromosome end maintenance
    • (doi:10.1093/hmg/ddl002)
    • McPherson, J. P. et al. 2006 A role for Brca1 in chromosome end maintenance. Hum. Mol. Genet. 15, 831-838. (doi:10.1093/hmg/ddl002)
    • (2006) Hum. Mol. Genet , vol.15 , pp. 831-838
    • McPherson, J.P.1
  • 24
    • 0037308404 scopus 로고    scopus 로고
    • Association between telomere length in blood and mortality in people aged 60 years or older
    • (doi:10.1016/S0140-6736(03)12384-7)
    • Cawthon, R. M., Smith, K. R., O'Brien, E., Sivatchenko, A. & Kerber, R. A. 2003 Association between telomere length in blood and mortality in people aged 60 years or older. Lancet 361, 393-395. (doi:10.1016/S0140-6736(03)12384-7)
    • (2003) Lancet , vol.361 , pp. 393-395
    • Cawthon, R.M.1    Smith, K.R.2    O'Brien, E.3    Sivatchenko, A.4    Kerber, R.A.5
  • 25
    • 16844384347 scopus 로고    scopus 로고
    • Telomere length predicts embryo fragmentation after in vitro fertilization in women: Toward a telomere theory of reproductive aging in women
    • (doi:10.1016/j.ajog.2005.01.036)
    • Keefe, D. L., Franco, S., Liu, L., Trimarchi, J., Cao, B., Weitzen, S., Agarwal, S. & Blasco, M. A. 2005 Telomere length predicts embryo fragmentation after in vitro fertilization in women: toward a telomere theory of reproductive aging in women. Am. J. Obstet. Gynecol. 192, 1256-1260. (doi:10.1016/j.ajog.2005.01.036)
    • (2005) Am. J. Obstet. Gynecol , vol.192 , pp. 1256-1260
    • Keefe, D.L.1    Franco, S.2    Liu, L.3    Trimarchi, J.4    Cao, B.5    Weitzen, S.6    Agarwal, S.7    Blasco, M.A.8
  • 26
    • 33744983280 scopus 로고    scopus 로고
    • The telomere theory of reproductive senescence in women
    • (doi:10.1097/01.gco.0000193019.05686.49)
    • Keefe, D. L., Marquard, K. & Liu, L. 2006 The telomere theory of reproductive senescence in women. Curr. Opin. Obstet. Gynecol. 18, 280-285. (doi:10.1097/01.gco.0000193019.05686.49)
    • (2006) Curr. Opin. Obstet. Gynecol , vol.18 , pp. 280-285
    • Keefe, D.L.1    Marquard, K.2    Liu, L.3
  • 27
    • 21744431507 scopus 로고    scopus 로고
    • Is telomere length one of the determinants of reproductive life span?
    • (doi:10.1007/s00404-004-0690-2)
    • Aydos, S. E., Elhan, A. H. & Tukun, A. 2005 Is telomere length one of the determinants of reproductive life span? Arch. Gynecol. Obstet. 272, 113-116. (doi:10.1007/s00404-004-0690-2)
    • (2005) Arch. Gynecol. Obstet , vol.272 , pp. 113-116
    • Aydos, S.E.1    Elhan, A.H.2    Tukun, A.3
  • 30
    • 0033610723 scopus 로고    scopus 로고
    • Pregnancy and risk of early breast cancer in carriers of BRCA1 and BRCA2
    • (doi:10.1016/S0140-6736(99) 04336-6)
    • Jernstrom, H. et al. 1999 Pregnancy and risk of early breast cancer in carriers of BRCA1 and BRCA2. Lancet 354, 1846-1850. (doi:10.1016/S0140-6736(99) 04336-6)
    • (1999) Lancet , vol.354 , pp. 1846-1850
    • Jernstrom, H.1
  • 32
    • 0042322237 scopus 로고    scopus 로고
    • Genetic testing for a BRCA1 mutation: Prophylactic surgery and screening behavior in women 2 years post testing
    • (doi:10.1002/ajmg.a.10102)
    • Botkin, J. R. et al. 2003 Genetic testing for a BRCA1 mutation: prophylactic surgery and screening behavior in women 2 years post testing. Am. J. Med. Genet. A 118, 201-209. (doi:10.1002/ajmg.a.10102)
    • (2003) Am. J. Med. Genet. A , vol.118 , pp. 201-209
    • Botkin, J.R.1
  • 33
    • 0035680432 scopus 로고    scopus 로고
    • Hormonal prevention of hereditary breast cancer
    • (doi:10.1111/j.1749-6632.2001.tb02726.x)
    • Narod, S. A. 2001 Hormonal prevention of hereditary breast cancer. Ann. NY Acad. Sci. 952, 36-43. (doi:10.1111/j.1749-6632.2001.tb02726.x)
    • (2001) Ann. NY Acad. Sci , vol.952 , pp. 36-43
    • Narod, S.A.1
  • 34
    • 28044451561 scopus 로고    scopus 로고
    • Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers
    • (doi:10.1002/ijc.21273)
    • Cullinane, C. A. 2005 Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers. Int. J. Cancer 117, 988-991. (doi:10.1002/ijc.21273)
    • (2005) Int. J. Cancer , vol.117 , pp. 988-991
    • Cullinane, C.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.