Antibiotic-impregnated catheters for the prevention of CSF shunt infections: A systematic review and meta-analysis

British Journal of Neurosurgery

Volumn 26, Issue 2, 2012, Pages 175-184

  Thomas, Rebecca ^a,b   Lee, Sharon ^a   Patole, Sanjay ^b,c   Rao, Shripada ^a,b,c  

^a PRINCESS MARGARET HOSPITAL FOR CHILDREN   (Australia)

^b KING EDWARD MEMORIAL HOSPITAL   (Australia)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Antibiotic impregnation; Cerebrospinal fluid; External ventricular drain; Infection; Review; Ventriculoperitoneal shunt

Indexed keywords

ANTIBIOTIC AGENT;

ANTIBIOTIC IMPREGNATED CATHETER; CATHETER; CENTRAL NERVOUS SYSTEM INFECTION; CEREBROSPINAL FLUID INFECTION; CEREBROSPINAL FLUID SHUNTING; EXTERNAL VENTRICULAR DRAIN; HUMAN; META ANALYSIS; PRIORITY JOURNAL; REVIEW; SYSTEMATIC REVIEW; VENTRICULO PERITONEAL SHUNT;

ADOLESCENT; ADULT; AGED; ANTI-BACTERIAL AGENTS; CATHETER-RELATED INFECTIONS; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID SHUNTS; CHILD; CHILD, PRESCHOOL; EQUIPMENT CONTAMINATION; HUMANS; INFANT; MIDDLE AGED; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84863389514     PISSN: 02688697     EISSN: 1360046X     Source Type: Journal    
DOI: 10.3109/02688697.2011.603856     Document Type: Review

References (40)

1. S imon TD, Hall M, Riva-Cambrin J, Albert JE, Jeffries HE, Lafleur B, et al Infection rates following initial cerebrospinal fluid shunt placement across pediatric hospitals in the United States. J Neurosurg Pediatr 2009;4:156-65.
2. Prusseit J, Simon M, von der Brelie C, Heep A, Molitor E, Volz S, et al Epidemiology, prevention and management of ventriculoperitoneal shunt infections in children. Pediatr Neurosurg 2009;45:325-36.
3. B lount JP, Campbell JA, Haines SJ. Complications in ventricular cerebrospinal fluid shunting. Neurosurg Clin N Am 1993;4: 633-56.
4. M cGirt MJ, Leveque JC, Wellons JC, 3rd, Villavicencio AT, Hopkins JS, Fuchs HE, et al Cerebrospinal fluid shunt survival and etiology of failures: a seven-year institutional experience. Pediatr Neurosurg 2002;36:248-55.
5. Walters BC, Hoffman HJ, Hendrick EB, Humphreys RP. Cerebrospinal fluid shunt infection. Influences on initial management and subsequent outcome. J Neurosurg 1984;60: 1014-21.
6. H arrop JS, Sharan AD, RatliffJ, Prasad S, Jabbour P, Evans JJ, e t al Impact of a standardized protocol and antibiotic-impregnated catheters on ventriculostomy infection rates in cerebrovascular patients. Neurosurgery 2010;67:187-91; discussion 91.
7. Eymann R, Chehab S, Strowitzki M, Steudel WI, Kiefer M. Clinical and economic consequences of antibiotic-impregnated cerebrospinal fluid shunt catheters. J Neurosurg Pediatr 2008;1:444-50.
8. Eymann R, Steudel WI, Kiefer M. Infection rate with application of an antibiotic-impregnated catheter for shunt implantation in children-a retrospective analysis. Klin Peadiatr 2009;221:69-73.
9. Bayston R, Ashraf W, Fisher L. Prevention of infection in neurosurgery: role of ' antimicrobial ' catheters. J Hosp Infect 2007;65 Suppl 2:39-42.
10. Ratilal B, Costa J, Sampaio C. Antibiotic prophylaxis for surgical introduction of intracranial ventricular shunts. Cochrane Database Syst Rev 2006;3:CD005365.
11. Gutierrez-Gonzalez R, Boto GR. Do antibiotic-impregnated catheters prevent infection in CSF diversion procedures? Review of the literature. J Infect 2010;61:9-20.
12. Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, et al Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 2000;283:2008-12.
13. , TetzlaffJ, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol 2009;62:1006-12.
14. Deeks JJ, Dinnes J, D ' Amico R, Sowden AJ, Sakarovitch C, Song F, et al Evaluating non-randomised intervention studies. Health Technol Assess 2003;7:iii-x, 1-173.
15. Agarwal N RS, Lee S, Keil A. Prevention of CSF shunt infections in the neonatal population: an audit of the new protocol. 14th Annual Congress of the Perinatal Society of Australia and New Zealand Wellington, New Zealand. J Pediatr Child Health 2010;46:57.
16. A lbanese A, De Bonis P, Sabatino G, Capone G, Marchese E, Vignati A, et al Antibiotic-impregnated ventriculo-peritoneal shunts in patients at high risk of infection. Acta Neurochir (Wien) 2009;151:1259-63.
17. A ryan HE, Meltzer HS, Park MS, Bennett RL, Jandial R, Levy ML. Initial experience with antibiotic-impregnated silicone catheters for shunting of cerebrospinal fluid in children. Childs Nerv Syst 2005;21:56-61.
18. Govender ST, Nathoo N, van Dellen JR. Evaluation of an antibioticimpregnated shunt system for the treatment of hydrocephalus. J Neurosurg 2003;99:831-9.
19. Gutierrez-Gonzalez R, Boto GR, Fernandez-Perez C, del Prado N. Protective effect of rifampicin and clindamycin impregnated devices against Staphylococcus spp. infection after cerebrospinal fluid diversion procedures. BMC Neurol 2010;10:93.
20. Gutierrez-Gonzalez R, Boto GR, Gonzalez N, Viudez I, Perez-Zamarron A, Rivero-Garvia M. [Effect of antibiotic-impregnated catheters on the incidence of infection after cerebrospinal fluid shunting]. Med Clin (Barc) 2008;131:121-4.
21. Hayhurst C, Cooke R, Williams D, Kandasamy J, O' Brien DF, Mallucci CL. The impact of antibiotic-impregnated catheters on shunt infection in children and neonates. Childs Nerv Syst 2008;24:557-62.
22. Kan P, Kestle J. Lack of efficacy of antibiotic-impregnated shunt systems in preventing shunt infections in children. Childs Nerv Syst 2007;23:773-7.
23. Muttaiyah S, Ritchie S, John S, Mee E, Roberts S. Efficacy of antibiotic-impregnated external ventricular drain catheters. J Clin Neurosci 2010;17:296-8.
24. Parker SL, Attenello FJ, Sciubba DM, Garces-Ambrossi GL, Ahn E, Weingart J, et al Comparison of shunt infection incidence in highrisk subgroups receiving antibiotic-impregnated versus standard shunts. Childs Nerv Syst 2009;25:77-83; discussion 85.
25. Pattavilakom A, Xenos C, Bradfield O, Danks RA. Reduction in shunt infection using antibiotic impregnated CSF shunt catheters: an Australian prospective study. J Clin Neurosci 2007;14:526-31.
26. Ritz R, Roser F, Morgalla M, Dietz K, Tatagiba M, Will BE. Do antibiotic-impregnated shunts in hydrocephalus therapy reduce the risk of infection? An observational study in 258 patients. BMC Infect Dis 2007;7:38.
27. Tamburrini G, Massimi L, Caldarelli M, Di Rocco C. Antibiotic impregnated external ventricular drainage and third ventriculostomy in the management of hydrocephalus associated with posterior cranial fossa tumours. Acta Neurochir (Wien) 2008;150:1049-55; discussion 55-6.
28. Wong GK, Poon WS, Ng SC, Ip M. The impact of ventricular catheter impregnated with antimicrobial agents on infections in patients with ventricular catheter: interim report. Acta Neurochir Suppl 2008;102:53-5.
29. Zabramski JM, Whiting D, Darouiche RO, Horner TG, Olson J, Robertson C, et al Efficacy of antimicrobial-impregnated external ventricular drain catheters: a prospective, randomized, controlled trial. J Neurosurg 2003;98:725-30.
30. Rivero-Garvia M, Marquez-Rivas J, Jimenez-Mejias ME, Neth O, Rueda-Torres AB. Reduction in external ventricular drain infection rate. Impact of a minimal handling protocol and antibioticimpregnated catheters. Acta neurochirurgica 2011;153:647-51.
31. Richards HK, Seeley HM, Pickard JD. Efficacy of antibioticimpregnated shunt catheters in reducing shunt infection: data from the United Kingdom Shunt Registry. J Neurosurg Pediatr 2009;4:389-93.
32. Sloffer CA, Augspurger L, Wagenbach A, Lanzino G. Antimicrobialimpregnated external ventricular catheters: does the very low infection rate observed in clinical trials apply to daily clinical practice? Neurosurgery 2005;56:1041-4; discussion 41-4.
33. Fichtner J, Guresir E, Seifert V, Raabe A. Efficacy of silver-bearing external ventricular drainage catheters: a retrospective analysis. J Neurosurg 2010;112:840-6.
34. Izci Y, Secer H, Akay C, Gonul E. Initial experience with silverimpregnated polyurethane ventricular catheter for shunting of cerebrospinal fluid in patients with infected hydrocephalus. Neurol Res 2009;31:234-7.
35. Lackner P, Beer R, Broessner G, Helbok R, Galiano K, Pleifer C, e t al Efficacy of silver nanoparticles-impregnated external ventricular drain catheters in patients with acute occlusive hydrocephalus. Neurocrit Care 2008;8:360-5.
36. Rozzelle CJ, Leonardo J, Li V. Antimicrobial suture wound closure for cerebrospinal fluid shunt surgery: a prospective, double-blinded, randomized controlled trial. J Neurosurg Pediatr 2008;2:111-7.
37. Hayashi T, Shirane R, Kato T, Tominaga T. Efficacy of intraoperative wound irrigation for preventing shunt infection. J Neurosurg Pediatr 2008;2:25-8.
38. W ong GK, Ip M, Poon WS, Mak CW, Ng RY. Antibioticsimpregnated ventricular catheter versus systemic antibiotics for prevention of nosocomial CSF and non-CSF infections: a prospective randomised clinical trial. J Neurol Neurosurg Psychiatry 2010;81:1064-7.
39. Jepsen P, Johnsen SP, Gillman MW, Sorensen HT. Interpretation of observational studies. Heart 2004;90:956-60.
40. http://www.who.int/ictrp/en/