Reduction in shunt infection using antibiotic impregnated CSF shunt catheters: An Australian prospective study

Journal of Clinical Neuroscience

Volumn 14, Issue 6, 2007, Pages 526-531

  Pattavilakom, Ananthababu ^a   Xenos, Chris ^a   Bradfield, Owen ^a   Danks, R Andrew ^b  

^a MONASH MEDICAL CENTRE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Antibiotic impregnated CSF shunt catheters; Ceftriaone; Clindamycin; CSF shunt infection; Rifampicin

Indexed keywords

ANTIBIOTIC AGENT; CEFTRIAXONE; CLINDAMYCIN; FLUCLOXACILLIN; RIFAMPICIN; VANCOMYCIN;

AGED; ARTICLE; AUSTRALIA; CATHETER; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID SHUNTING; CLINICAL PRACTICE; CONTROLLED STUDY; FEMALE; GRAM NEGATIVE INFECTION; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROPHYLAXIS; RISK ASSESSMENT; SCHOOL CHILD; SHUNT INFECTION;

AGED; ANTI-BACTERIAL AGENTS; AUSTRALIA; CATHETERS, INDWELLING; CEREBROSPINAL FLUID SHUNTS; CHI-SQUARE DISTRIBUTION; CHILD; CLINDAMYCIN; DELAYED-ACTION PREPARATIONS; DRUG THERAPY, COMBINATION; FOLLOW-UP STUDIES; HUMANS; INFANT, NEWBORN; INFECTION CONTROL; PROSPECTIVE STUDIES; PROSTHESIS-RELATED INFECTIONS; RIFAMPIN; STATISTICS, NONPARAMETRIC; SURGICAL WOUND INFECTION; TREATMENT OUTCOME;

EID: 34047272859     PISSN: 09675868     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jocn.2006.11.003     Document Type: Article

References (21)

1. Govender S.T., Nathoo N., and Van Dellen J.R. Evaluation of an antibiotic-impregnated shunt system for the treatment of hydrocephalus. J Neurosurg 101 (2003) 831-839
2. Kanev P.M., and Sheehan J.M. Reflections on shunt infection. Pediatr Neurosurg 96 (2003) 285-290
3. McGirt M.J., Leveque J.C., Wellons III J.C., et al. Cerebrospinal fluid shunt survival and etiology of failures: a seven-year institutional experience. Pediatr Neurosurg 36 (2002) 248-255
4. McGirt M.J., Zaas A., Fuchs H.E., et al. Risk factors for pediatric ventriculoperitoneal shunt infection and predictors of infectious pathogens. Clin Infect Dis 36 (2003) 858-862
5. Pople I.K., Bayston R., and Hayward R.D. Infection of cerebrospinal fluid shunts in infants: a study of etiological factors. J Neurosurg 77 (1992) 29-36
6. Shapiro S., Boaz J., Kleiman M., et al. Origin of organisms infecting ventricular shunts. Neurosurgery 22 (1988) 868-872
7. Van Noort R., and Bayston R. Mechanical properties of antibacterial silicone rubber for hydrocephalus shunts. J Biomed Mater Res 13 (1979) 623-630
8. Bayston R. Preliminary studies on the impregnation of silastic elastomers with antimicrobial substances. Dev Med Child Neurol Suppl 37 (1976) 50-54
9. Bayston R., Grove N., Siegel J., et al. Prevention of hydrocephalus shunt catheter colonisation in vitro by impregnation with antimicrobials. J Neurol Neurosurg Psychiatry 52 (1989) 605-609
10. Bayston R., and Milner R.D. Antimicrobial activity of silicone rubber used in hydrocephalus shunts, after impregnation with antimicrobial substances. J Clin Pathol 34 (1981) 1057-1062
11. Abed W.T., Alavijeh M.S., Bayston R., et al. An evaluation of the epileptogenic properties of a rifampicin/clindamycin-impregnated shunt catheter. Br J Neurosurg 8 (1994) 725-730
12. Bayston R., and Lambert E. Duration of protective activity of cerebrospinal fluid shunt catheters impregnated with antimicrobial agents to prevent bacterial catheter-related infection. J Neurosurg 87 (1997) 247-251
13. Aryan H.E., Meltzer H.S., Park M.S., et al. Initial experience with antibiotic-impregnated silicone catheters for shunting of cerebrospinal fluid in children. Childs Nerv Syst 21 (2005) 56-61
14. Sciubba D.M., Stuart R.M., McGirt M.J., et al. Effect of antibiotic-impregnated shunt catheters in decreasing the incidence of shunt infection in the treatment of hydrocephalus. J Neurosurg 103 Suppl.2 (2005) 131-136
15. Ashpole R.D. New instrumentation for assembly of shunt systems. Eur J Pediatr Surg 2 Suppl.1 (1992) 6
16. Odio C., McCracken Jr. G.H., and Nelson J.D. CSF shunt infections in pediatrics. A seven-year experience. Am J Dis Child 138 (1984) 1103-1s108
17. Wang K.W., Chang W.N., Shih T.Y., et al. Infection of cerebrospinal fluid shunts: causative pathogens, clinical features, and outcomes. Jpn J Infect Dis 57 (2004) 44-48
18. Turgut M., Alabaz D., Erbey F., et al. Cerebrospinal fluid shunt infections in children. Pediatr Neurosurg 41 (2005) 131-136
19. Ronan A., Hogg G.G., and Klug G.L. Cerebrospinal fluid shunt infections in children. Pediatr Infect Dis J 14 (1995) 782-786
20. Choux M., Genitori L., Lang D., et al. Shunt implantation: reducing the incidence of shunt infection. J Neurosurg 77 (1992) 875-880
21. Pattavilakom A., Kotasnas D., Korman T.M., et al. Duration of in vivo antimicrobial activity of antibiotic-impregnated cerebrospinal fluid catheters. Neurosurgery 58 (2006) 930-935