Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1

Journal of Medicinal Chemistry

Volumn 55, Issue 6, 2012, Pages 2803-2810

  Larson, Eric T ^a,c   Ojo, Kayode K ^b   Murphy, Ryan C ^b   Johnson, Steven M ^b   Zhang, Zhongsheng ^a   Kim, Jessica E ^a   Leibly, David J ^b   Fox, Anna M W ^b   Reid, Molly C ^b   Dale, Edward J ^b   Perera, B Gayani K ^b   Kim, Jae ^a   Hewitt, Stephen N ^b   Hol, Wim G J ^a   Verlinde, Christophe L M J ^a   Fan, Erkang ^a   Van Voorhis, Wesley C ^b   Maly, Dustin J ^b   Merritt, Ethan A ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; PROTEIN KINASE C; PYRAZOLOPYRIMIDINE DERIVATIVE; SCAFFOLD PROTEIN;

APICOMPLEXA; ARTICLE; CHROMOSOME POSITIONING; CRYPTOSPORIDIUM PARVUM; CRYSTAL STRUCTURE; HUMAN; NONHUMAN; ONCOGENE SRC; TOXOPLASMA GONDII;

ANTIPROTOZOAL AGENTS; BENZIMIDAZOLES; CALCIUM; CRYPTOSPORIDIUM PARVUM; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTOZOAN PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TOXOPLASMA;

EID: 84863387278     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm201725v     Document Type: Article

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