Synthesis of [18F]-labeled (6-fluorohexyl)triphenylphosphonium cation as a potential agent for myocardial imaging using positron emission tomography

Bioconjugate Chemistry

Volumn 23, Issue 3, 2012, Pages 431-437

  Kim, Dong Yeon ^a,b   Kim, Hee Jung ^a   Yu, Kook Hyun ^a   Min, Jung Joon ^b,c  

^a Dongguk University   (South Korea)

^b Chonnam National University   (South Korea)

^c Chonnam National University Medical School   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; FLUORINE COMPOUNDS; POSITIVE IONS; POSITRON EMISSION TOMOGRAPHY; POSITRONS; POTASH; SALTS;

HYDROPHOBICS; IMAGING AGENT; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAS; NON-INVASIVE IMAGING; NUCLEOPHILIC SUBSTITUTION REACTIONS; PHOSPHONIUM SALTS; REFERENCE COMPOUNDS; SYNTHESISED; TRANSMEMBRANE POTENTIALS;

MITOCHONDRIA;

(6 FLUOROHEXYL)TRIPHENYLPHOSPHONIUM; (6 FLUOROHEXYL)TRIPHENYLPHOSPHONIUM F 18; CATION; FLUORINE 18; OXYGEN 18; PHOSPHONIUM DERIVATIVE; TETRAPHENYLPHOSPHONIUM; TRACER; TRITIUM; UNCLASSIFIED DRUG; WATER; (6-FLUOROHEXYL)TRIPHENYLPHOSPHONIUM; DIAGNOSTIC AGENT; FLUORINE; PHOSPHINE DERIVATIVE; RADIOPHARMACEUTICAL AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL CULTURE; CHEMICAL STRUCTURE; CORONARY ARTERY DISEASE; CYCLOTRON; DEVICES; DRUG CLEARANCE; DRUG STABILITY; DRUG UPTAKE; ELECTROSPRAY MASS SPECTROMETRY; FAST ATOM BOMBARDMENT MASS SPECTROMETRY; FIBROBLAST CULTURE; HEART; HEART INFARCTION; HEART MITOCHONDRION; HEART MUSCLE; HEART MUSCLE CELL; HEART SCINTISCANNING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMAGING SYSTEM; IRRADIATION; ISOTOPE LABELING; LIPOPHILICITY; LIQUID SCINTILLATION COUNTING; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR SENSOR; MOUSE; NONHUMAN; PARTITION COEFFICIENT; POSITRON EMISSION TOMOGRAPHY; PROTON NUCLEAR MAGNETIC RESONANCE; RADIOACTIVITY; RADIOCHEMISTRY; RAT; SPECTROMETER; SYNTHESIS; TISSUE DISTRIBUTION; ANIMAL; BAGG ALBINO MOUSE; HISTOLOGY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

MUS; RATTUS;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLUORINE RADIOISOTOPES; HEART; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED BALB C; PHOSPHINES; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT;

EID: 84863384126     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc2004439     Document Type: Article

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