Impaired associative taste learning and abnormal brain activation in kinase-defective eEF2K mice

Learning and Memory

Volumn 19, Issue 3, 2012, Pages 116-125

  Gildish, Iness ^a   Manor, David ^a   David, Orit ^a   Sharma, Vijendra ^a   Williams, David ^b   Agarwala, Usha ^c   Wang, Xuemin ^c   Kenney, Justin W ^c   Proud, Chris G ^b,c   Rosenblum, Kobi ^a  

^a UNIVERSITY OF HAIFA   (Israel)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ELONGATION FACTOR 2; ELONGATION FACTOR 2 KINASE; MANGANESE; THREONINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASSOCIATIVE MEMORY; AVERSIVE BEHAVIOR; BRAIN CORTEX; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HIPPOCAMPUS; IMAGE ENHANCEMENT; LEARNING DISORDER; MALE; MEMORY CONSOLIDATION; MEMORY DISORDER; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATE DEPENDENT LEARNING; TASTE;

ANIMALS; ASSOCIATION LEARNING; BEHAVIOR, ANIMAL; BRAIN CHEMISTRY; CONDITIONING (PSYCHOLOGY); ELONGATION FACTOR 2 KINASE; MAGNETIC RESONANCE IMAGING; MANGANESE; MEMORY; MICE; PHOSPHORYLATION; TASTE PERCEPTION;

EID: 84863372213     PISSN: 10720502     EISSN: 15495485     Source Type: Journal    
DOI: 10.1101/lm.023937.111     Document Type: Article

References (49)

1. Abel T, Lattal KM. 2001. Molecular mechanisms of memory acquisition, consolidation, and retrieval. Curr Opin Neurobiol 11: 180-187. (Pubitemid 32289404)
2. Alberini CM. 2005. Mechanisms of memory stabilization: Are consolidation and reconsolidation similar or distinct processes? Trends Neurosci 28: 51-56. (Pubitemid 40038802)
3. Aoki I, Naruse S, Tanaka C. 2004. Manganese-enhanced magnetic resonance imaging (MEMRI) of brain activity and applications to early detection of brain ischemia. NMR Biomed 17: 569-580. (Pubitemid 40124782)
4. Auerbach BD, Osterweil EK, Bear MF. 2011. Mutations causing syndromic autism define an axis of synaptic pathophysiology. Nature 480: 63-68.
5. Bailey CH, Bartsch D, Kandel ER. 1996. Toward a molecular definition of long-term memory storage. Proc Natl Acad Sci 93: 13445-13452. (Pubitemid 26424140)
6. Belelovsky K, Elkobi A, Kaphzan H, Nairn AC, Rosenblum K. 2005. A molecular switch for translational control in taste memory consolidation. Eur J Neurosci 22: 2560-2568. (Pubitemid 41758998)
7. Belelovsky K, Maroun M, Rosenblum K. 2007. MAPK activation in the hippocampus in vivo is correlated with experimental setting. Neurobiol Learn Mem 88: 58-64. (Pubitemid 46809810)
8. Belelovsky K, Kaphzan H, Elkobi A, Rosenblum K. 2009. Biphasic activation of the mTOR pathway in the gustatory cortex is correlated with and necessary for taste learning. J Neurosci 29: 7424-7431.
9. Bock N, Paiva F, Silva A. 2008. Fractionated manganese-enhanced MRI. NMR Biomed 21: 473-478. (Pubitemid 351895435)
10. Bureš JB, Bermúdez-Rattoni F, Yamamoto T. 1998. Conditioned taste aversion. Memory of special kind. Oxford University Press, New York.
11. Carlberg U, Nilsson A, Nygard O. 1990. Functional properties of phosphorylated elongation factor 2. Eur J Biochem 191: 639-645. (Pubitemid 20265772)
12. Chotiner JK, Khorasani H, Nairn AC, O'Dell TJ, Watson JB. 2003. Adenylyl cyclase-dependent form of chemical long-term potentiation triggers translational regulation at the elongation step. Neuroscience 116: 743-752. (Pubitemid 36160570)
13. Costa-Mattioli M, Gobert D, Stern E, Gamache K, Colina R, Cuello C, Sossin W, Kaufman R, Pelletier J, Rosenblum K, et al. 2007. eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory. Cell 129: 195-206. (Pubitemid 46507591)
14. Debiec J, LeDoux JE, Nader K. 2002. Cellular and systems reconsolidation in the hippocampus. Neuron 36: 527-538. (Pubitemid 35291098)
15. de Sousa PL, de Souza SL, Silva AC, de Souza RE, de Castro RM. 2007. Manganese-enhanced magnetic resonance imaging (MEMRI) of rat brain after systemic administration of MnCl2: Changes in T1 relaxation times during postnatal development. J Magn Reson Imaging 25: 32-38. (Pubitemid 46095198)
16. Dudai Y. 2004. The neurobiology of consolidations, or, how stable is the engram? Annu Rev Psychol 55: 51-86. (Pubitemid 40517787)
17. Elkobi A, Ehrlich I, Belelovsky K, Barki-Harrington L, Rosenblum K. 2008. ERK-dependent PSD-95 induction in the gustatory cortex is necessary for taste learning but not retrieval. Nat Neurosci 11: 1149-1151.
18. Eschenko O, Canals S, Simanova I, Beyerlein M, Murayama Y, Logothetis NK. 2009. Mapping of functional brain activity in freely behaving rats during voluntary running using manganese-enhanced MRI: Implication for longitudinal studies. Neuroimage 49: 2544-2555.
19. Franklin K, Paxinos G. 2007. The mouse brain in stereotaxic coordinates, 3rd ed. Academic Press, New York.
20. Gal-Ben-Ari S, Rosenblum K. 2011. Molecular mechanisms underlying memory consolidation of taste information in the cortex. Front Behav Neurosci 5: 87. doi: 10.3389/fnbeh.2011.00087.
21. Grünecker B, Kaltwasser SF, Peterse Y, Sämann PG, Schmidt MV, Wotjak CT, Czisch M. 2010. Fractionated manganese injections: Effects on MRI contrast enhancement and physiological measures in C57BL/6 mice. NMR Biomed 23: 913-921.
22. Houpt TA, Berlin R. 1998. Rapid labile and protein synthesis-independent short-term memory in conditioned taste aversion. Learn Mem 6: 37-46. (Pubitemid 29164544)
23. Inui-Yamamoto C, Yoshioka Y, Inui T, Sasaki KS, Ooi Y, Ueda K, Seiyama A, Ohzawa I. 2010. The brain mapping of the retrieval of conditioned taste aversion memory using manganese-enhanced magnetic resonance imaging in rats. Neuroscience 167: 199-204.
24. Kanhema T, Dagestad G, Panja D, Tiron A, Messaoudi E, Ha° vik B, Ying SW, Nairn AC, Sonenberg N, Bramham CR. 2006. Dual regulation of translation initiation and peptide chain elongation during BDNF-induced LTP in vivo: Evidence for compartment-specific translation control. J Neurochem 99: 1328-1337. (Pubitemid 44730089)
25. Kuo YT, Herlihy AH, So PW, Bhakoo KK, Bell JD. 2005. In vivo measurements of T1 relaxation times in mouse brain associated with different modes of systemic administration of manganese chloride. J Magn Reson Imaging 21: 334-339. (Pubitemid 40446425)
26. Lin YJ, Koretsky AP. 1997. Manganese ion enhances T1-weighted MRI during brain activation: An approach to direct imaging of brain function. Magn Reson Med 38: 378-388. (Pubitemid 27386335)
27. Marin P, Nastiuk KL, Daniel N, Girault JA, Czernik AJ, Glowinski J, Nairn AC, Premont J. 1997. Glutamate-dependent phosphorylation of elongation factor-2 and inhibition of protein synthesis in neurons. J Neurosci 17: 3445-3454. (Pubitemid 27200574)
28. Merhav M, Rosenblum K. 2008. Facilitation of taste memory acquisition by experiencing previous novel taste is protein-synthesis dependent. Learn Mem 15: 501-507. (Pubitemid 352008672)
29. Miller SA, Dykes DD, Polesky HF. 1988. A simple salting out procedure for extracting DNA from human nucleated cells. Nucl Ac Res 16: 1215. doi: 10.1093/nar/16.3.1215.
30. Núñez-Jaramillo L, Ramírez-Lugo L, Herrera-MoralesW, Miranda MI. 2010. Taste memory formation: Latest advances and challenges. Behav Brain Res 207: 232-248.
31. Park S, Park JM, Kim S, Kim JA, Shepherd JD, Smith-Hicks CL, Chowdhury S, Kaufmann W, Kuhl D, Ryazanov AG, et al. 2008. Elongation factor 2 and fragile Xmental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD. Neuron 59: 70-83. (Pubitemid 351905855)
32. Pautler RG. 2004. In vivo, trans-synaptic tract-tracing utilizing manganese-enhanced magnetic resonance imaging (MEMRI). NMR Biomed 17: 595-601. (Pubitemid 40124784)
33. Pautler RG, Silva AC, Koretsky AP. 1998. In vivo neuronal tract tracing using manganese-enhanced magnetic resonance imaging. Magn Reson Med 40: 740-748. (Pubitemid 28493653)
34. Proud CG. 2000. Control of elongation phase of protein synthesis. In Translation control of gene expression (ed. N Sonenberg et al.), pp. 719-739. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
35. Redpath NT, Proud CG. 1993. Cyclic AMP-dependent protein kinase phosphorylates rabbit reticulocyte elongation factor-2 kinase and induces calcium-independent activity. Biochem J 293: 31-34. (Pubitemid 23223143)
36. Richter JD, Klann E. 2009. Making synaptic plasticity and memory last: Mechanisms of translational regulation. Genes Dev 23: 1-11.
37. Rosenblum K. 2008. Conditioned taste aversion and taste learning: Molecular mechanisms. In Learning and memory: A comprehensive reference (ed. J Byrne), pp. 217-234. Elsevier Academic Press, Waltham, MA.
38. Rosenblum K, Meiri N, Dudai Y. 1993. Taste memory: The role of protein synthesis in gustatory cortex. Behav Neur Biol 59: 49-56. (Pubitemid 23092523)
39. Scheetz AJ, Nairn AC, Constantine-Paton M. 2000. NMDA receptor-mediated control of protein synthesis at developing synapses. Nat Neurosci 3: 211-216. (Pubitemid 30140781)
40. Serrano F, Deshazer M, Smith KD, Ananta JS, Wilson LJ, Pautler RG. 2008. Assessing transneuronal dysfunction utilizing manganese-enhanced MRI (MEMRI). Magn Reson Med 60: 169-175. (Pubitemid 351956621)
41. Silva AC, Bock NA. 2008. Manganese-enhanced MRI: An exceptional tool in translational neuroimaging. Schizophr Bull 34: 595-604. (Pubitemid 351957573)
42. Silva AC, Lee JH, Aoki I, Koretsky AP. 2004. Manganese-enhanced magnetic resonance imaging (MEMRI): Methodological and practical considerations. NMR Biomed 17: 532-543. (Pubitemid 40124779)
43. Smith EM, Proud CG. 2008. cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner. EMBO J 27: 1005-1016. (Pubitemid 351508149)
44. Sonenberg N, Hershey WB, Mathews MB. 2000. Translation control of gene expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
45. Sutton M, Taylor A, Ito H, Pham A, Schuman E. 2007. Postsynaptic decoding of neural activity: eEF2 as a biochemical sensor coupling miniature synaptic transmission to local protein synthesis. Neuron 55: 648-661. (Pubitemid 47223643)
46. Verpelli C, Piccoli G, Zanchi A, Gardoni F, Huang K, Brambilla D, Di Luca M, Battaglioli E, Sala C. 2010. Synaptic activity controls dendritic spine morphology by modulating eEF2-dependent BDNF synthesis. J Neurosci 30: 5830-5842.
47. Weng JC, Chen JH, Yang PF, Tseng WY. 2007. Functional mapping of rat barrel activation following whisker stimulation using activity-induced manganese-dependent contrast. Neuroimage 36: 1179-1188.
48. Yamaguchi H, Matsushita M, Nairn AC, Kuriyan J. 2001. Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity. Mol Cell 7: 1047-1057. (Pubitemid 32525751)
49. Yu X, Nieman BJ, Sudarov A, Szulc KU, Abdollahian DJ, Bhatia N, Lalwani AK, Joyner AL, Turnbull DH. 2011. Morphological and functional midbrain phenotypes in Fibroblast Growth Factor 17 mutant mice detected by Mn-enhanced MRI. Neuroimage 56: 1251-1258.