메뉴 건너뛰기




Volumn 32, Issue 3, 2012, Pages 865-872

SN-38 overcomes chemoresistance of colorectal cancer cells induced by hypoxia, through HIF1alpha

Author keywords

Colorectal cancer; Hypoxia; Hypoxia inducible factor; Irinotecan; SN 38

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; FLUOROURACIL; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXALIPLATIN;

EID: 84863352583     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (30)

References (39)
  • 1
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia-a key regulatory factor in tumour growth
    • Harris AL: Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer 2: 38-47, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 2
    • 29344443251 scopus 로고    scopus 로고
    • The distribution of the anticancer drug doxorubicin in relation to blood vessels in solid tumors
    • DOI 10.1158/1078-0432.CCR-05-1664
    • Primeau AJ, Rendon A, Hedley D, Lilge L and Tannock IF: The distribution of the anticancer drug doxorubicin in relation to blood vessels in solid tumors. Clin Cancer Res 11: 8782-8788, 2005. (Pubitemid 43005929)
    • (2005) Clinical Cancer Research , vol.11 , Issue.24 , pp. 8782-8788
    • Primeau, A.J.1    Rendon, A.2    Hedley, D.3    Lilge, L.4    Tannock, I.F.5
  • 3
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL: Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3: 721-732, 2003.
    • (2003) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 5
    • 35048875691 scopus 로고    scopus 로고
    • Evaluation of HIF-1 inhibitors as anticancer agents
    • Semenza GL: Evaluation of HIF-1 inhibitors as anticancer agents. Drug Discov Today 12: 853-859, 2007.
    • (2007) Drug Discov Today , vol.12 , pp. 853-859
    • Semenza, G.L.1
  • 6
    • 73249130655 scopus 로고    scopus 로고
    • Expression of HIF-1alpha and VEGF in colorectal cancer: Association with clinical outcomes and prognostic implications
    • doi: 10.1186/1471-2407-9-432
    • Cao D, Hou M, Guan YS, Jiang M, Yang Y and Gou HF: Expression of HIF-1alpha and VEGF in colorectal cancer: association with clinical outcomes and prognostic implications. BMC Cancer 9: doi: 10.1186/1471-2407-9-432, 2009.
    • (2009) BMC Cancer , vol.9
    • Cao, D.1    Hou, M.2    Guan, Y.S.3    Jiang, M.4    Yang, Y.5    Gou, H.F.6
  • 8
    • 78650232336 scopus 로고    scopus 로고
    • Clinicopathological significance of p53, hypoxia-inducible factor 1alpha, and vascular endothelial growth factor expression in colorectal cancer
    • Kwon HC, Kim SH, Oh SY, Lee S, Kwon KA, Choi HJ, Park KJ, Kim HJ and Roh MS: Clinicopathological significance of p53, hypoxia-inducible factor 1alpha, and vascular endothelial growth factor expression in colorectal cancer. Anticancer Res 30: 4163-4168, 2010.
    • (2010) Anticancer Res , vol.30 , pp. 4163-4168
    • Kwon, H.C.1    Kim, S.H.2    Oh, S.Y.3    Lee, S.4    Kwon, K.A.5    Choi, H.J.6    Park, K.J.7    Kim, H.J.8    Roh, M.S.9
  • 10
    • 84855179551 scopus 로고    scopus 로고
    • Carbonic anhydrase IX, hypoxia-inducible factor-1alpha, ezrin and glucose transporter-1 as predictors of disease outcome in rectal cancer: Multivariate Cox survival models following data reduction by principal component analysis of the clinicopathological predictors
    • Korkeila EA, Sundstrom J, Pyrhonen S and Syrjanen K: Carbonic anhydrase IX, hypoxia-inducible factor-1alpha, ezrin and glucose transporter-1 as predictors of disease outcome in rectal cancer: multivariate Cox survival models following data reduction by principal component analysis of the clinicopathological predictors. Anticancer Res 31: 4529-4535, 2011.
    • (2011) Anticancer Res , vol.31 , pp. 4529-4535
    • Korkeila, E.A.1    Sundstrom, J.2    Pyrhonen, S.3    Syrjanen, K.4
  • 11
    • 12144287046 scopus 로고    scopus 로고
    • Hypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and -Independent Mechanisms and Contributes to Drug Resistance
    • DOI 10.1128/MCB.24.7.2875-2889.2004
    • Erler JT, Cawthorne CJ, Williams KJ, Koritzinsky M, Wouters BG, Wilson C, Miller C, Demonacos C, Stratford IJ, and Dive C: Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance. Mol Cell Biol 24: 2875-2889, 2004. (Pubitemid 38381277)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.7 , pp. 2875-2889
    • Erler, J.T.1    Cawthorne, C.J.2    Williams, K.J.3    Koritzinsky, M.4    Wouters, B.G.5    Wilson, C.6    Miller, C.7    Demonacos, C.8    Stratford, I.J.9    Dive, C.10
  • 12
    • 58549084773 scopus 로고    scopus 로고
    • Hypoxia induces resistance to 5-fluorouracil in oral cancer cells via G(1) phase cell cycle arrest
    • Yoshiba S, Ito D, Nagumo T, Shirota T, Hatori M and Shintani S: Hypoxia induces resistance to 5-fluorouracil in oral cancer cells via G(1) phase cell cycle arrest. Oral Oncol 45: 109-115, 2009.
    • (2009) Oral Oncol , vol.45 , pp. 109-115
    • Yoshiba, S.1    Ito, D.2    Nagumo, T.3    Shirota, T.4    Hatori, M.5    Shintani, S.6
  • 14
    • 77954761483 scopus 로고    scopus 로고
    • Suppression of hypoxia-induced HIF-1alpha accumulation by VEGFR inhibitors: Different profiles of AAL993 versus SU5416 and KRN633
    • Ban HS, Uno M and Nakamura H: Suppression of hypoxia-induced HIF-1alpha accumulation by VEGFR inhibitors: Different profiles of AAL993 versus SU5416 and KRN633. Cancer Lett 296: 17-26, 2010.
    • (2010) Cancer Lett , vol.296 , pp. 17-26
    • Ban, H.S.1    Uno, M.2    Nakamura, H.3
  • 15
    • 77951581527 scopus 로고    scopus 로고
    • Inhibition of metastasis, angiogenesis, and tumor growth by Chinese herbal cocktail Tien-Hsien Liquid
    • doi: 10.1186/1471-2407-10-175
    • Chia JS, Du JL, Hsu WB, Sun A, Chiang CP and Wang WB: Inhibition of metastasis, angiogenesis, and tumor growth by Chinese herbal cocktail Tien-Hsien Liquid. BMC Cancer 10: doi: 10.1186/1471-2407-10-175, 2010.
    • (2010) BMC Cancer , vol.10
    • Chia, J.S.1    Du, J.L.2    Hsu, W.B.3    Sun, A.4    Chiang, C.P.5    Wang, W.B.6
  • 16
    • 78149432961 scopus 로고    scopus 로고
    • Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21
    • doi: 10.1186/1748-717X-5-107
    • El-Khatib M, Geara F, Haddadin MJ, and Gali-Muhtasib H: Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21. Radiat Oncol 5: doi: 10.1186/1748-717X-5-107, 2010.
    • (2010) Radiat Oncol , vol.5
    • El-Khatib, M.1    Geara, F.2    Haddadin, M.J.3    Gali-Muhtasib, H.4
  • 18
    • 34547098129 scopus 로고    scopus 로고
    • Targeting hypoxia cell signaling for cancer therapy
    • Melillo G: Targeting hypoxia cell signaling for cancer therapy. Cancer Metastasis Rev 26: 341-352, 2007.
    • (2007) Cancer Metastasis Rev , vol.26 , pp. 341-352
    • Melillo, G.1
  • 19
    • 79953201844 scopus 로고    scopus 로고
    • Noscapine sensitizes chemoresistant ovarian cancer cells to cisplatin through inhibition of HIF-1alpha
    • Su W, Huang L, Ao Q, Zhang Q, Tian X, Fang Y and Lu Y: Noscapine sensitizes chemoresistant ovarian cancer cells to cisplatin through inhibition of HIF-1alpha. Cancer Lett 305: 94-99, 2011.
    • (2011) Cancer Lett , vol.305 , pp. 94-99
    • Su, W.1    Huang, L.2    Ao, Q.3    Zhang, Q.4    Tian, X.5    Fang, Y.6    Lu, Y.7
  • 20
    • 84895521117 scopus 로고    scopus 로고
    • Scutellaria barbata inhibits angiogenesis through downregulation of HIF-1 alpha in lung tumor
    • doi: 10.1002/tox.21763
    • Shiau AL, Shen YT, Hsieh JL, Wu CL and Lee CH: Scutellaria barbata inhibits angiogenesis through downregulation of HIF-1 alpha in lung tumor. Environ Toxicol doi: 10.1002/tox.21763, 2012.
    • (2012) Environ Toxicol
    • Shiau, A.L.1    Shen, Y.T.2    Hsieh, J.L.3    Wu, C.L.4    Lee, C.H.5
  • 21
    • 0041464531 scopus 로고    scopus 로고
    • Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells
    • Palayoor ST, Tofilon PJ and Coleman CN: Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells. Clin Cancer Res 9: 3150-3157, 2003. (Pubitemid 37006311)
    • (2003) Clinical Cancer Research , vol.9 , Issue.8 , pp. 3150-3157
    • Palayoor, S.T.1    Tofilon, P.J.2    Coleman, C.N.3
  • 22
    • 33745242315 scopus 로고    scopus 로고
    • Antiangiogenic potential of the mammalian target of rapamycin inhibitor temsirolimus
    • DOI 10.1158/0008-5472.CAN-05-2825
    • Del Bufalo D, Ciuffreda L, Trisciuoglio D, Desideri M, Cognetti F, Zupi G and Milella M: Antiangiogenic potential of the Mammalian target of rapamycin inhibitor temsirolimus. Cancer Res 66: 5549-5554, 2006. (Pubitemid 43927103)
    • (2006) Cancer Research , vol.66 , Issue.11 , pp. 5549-5554
    • Del, B.D.1    Ciuffreda, L.2    Trisciuoglio, D.3    Desideri, M.4    Cognetti, F.5    Zupi, G.6    Milella, M.7
  • 23
    • 77955038334 scopus 로고    scopus 로고
    • The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex
    • Li X and Fan Z: The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex. Cancer Res 70: 5942-5952, 2010.
    • (2010) Cancer Res , vol.70 , pp. 5942-5952
    • Li, X.1    Fan, Z.2
  • 25
    • 0017692623 scopus 로고
    • Partial synchronization of L1210 cells by 5-fluorouracil and its use in drug combinations
    • Bhuyan BK, Blowers CL, Neil GL, Bono VH and Day KJ: Partial synchronization of L1210 cells by 5-fluorouracil and its use in drug combinations. Cancer Res 37: 3204-3208, 1977. (Pubitemid 8169979)
    • (1977) Cancer Research , vol.37 , Issue.9 , pp. 3204-3208
    • Bhuyan, B.K.1    Blowers, C.L.2    Neil, G.L.3
  • 26
    • 50449109440 scopus 로고    scopus 로고
    • Overcoming S-phase checkpoint-mediated resistance: Sequence-dependent synergy of gemcitabine and 7-ethyl-10-hydroxycamptothecin (SN-38) in human carcinoma cell lines
    • Galvez-Peralta M, Dai NT, Loegering DA, Flatten KS, Safgren SL, Wagner JM, Ames MM, Karnitz LM and Kaufmann SH: Overcoming S-phase checkpoint-mediated resistance: sequence-dependent synergy of gemcitabine and 7-ethyl-10- hydroxycamptothecin (SN-38) in human carcinoma cell lines. Mol Pharmacol 74: 724-735, 2008.
    • (2008) Mol Pharmacol , vol.74 , pp. 724-735
    • Galvez-Peralta, M.1    Dai, N.T.2    Loegering, D.A.3    Flatten, K.S.4    Safgren, S.L.5    Wagner, J.M.6    Ames, M.M.7    Karnitz, L.M.8    Kaufmann, S.H.9
  • 27
    • 48849114378 scopus 로고    scopus 로고
    • Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential
    • Wallin A, Svanvik J, Holmlund B, Ferreud L and Sun XF: Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential. Oncol Rep 19: 1493-1498, 2008.
    • (2008) Oncol Rep , vol.19 , pp. 1493-1498
    • Wallin, A.1    Svanvik, J.2    Holmlund, B.3    Ferreud, L.4    Sun, X.F.5
  • 29
    • 77950207236 scopus 로고    scopus 로고
    • Suppression of cyclin D1 by hypoxia-inducible factor-1 via direct mechanism inhibits the proliferation and 5-fluorouracil-induced apoptosis of A549 cells
    • Wen W, Ding J, Sun W, Wu K, Ning B, Gong W, He G, Huang S, Ding X, Yin P, Chen L, Liu Q, Xie W and Wang H: Suppression of cyclin D1 by hypoxia-inducible factor-1 via direct mechanism inhibits the proliferation and 5-fluorouracil-induced apoptosis of A549 cells. Cancer Res 70: 2010-2019, 2010.
    • (2010) Cancer Res , vol.70 , pp. 2010-2019
    • Wen, W.1    Ding, J.2    Sun, W.3    Wu, K.4    Ning, B.5    Gong, W.6    He, G.7    Huang, S.8    Ding, X.9    Yin, P.10    Chen, L.11    Liu, Q.12    Xie, W.13    Wang, H.14
  • 30
    • 33845605116 scopus 로고    scopus 로고
    • The involvement of hypoxia-inducible factor-1alpha in the susceptibility to gamma-rays and chemotherapeutic drugs of oral squamous cell carcinoma cells
    • DOI 10.1002/ijc.22294
    • Sasabe E, Zhou X, Li D, Oku N, Yamamoto T and Osaki T: The involvement of hypoxia-inducible factor-1alpha in the susceptibility to gamma-rays and chemotherapeutic drugs of oral squamous cell carcinoma cells. Int J Cancer 120: 268-277, 2007. (Pubitemid 44956835)
    • (2007) International Journal of Cancer , vol.120 , Issue.2 , pp. 268-277
    • Sasabe, E.1    Zhou, X.2    Li, D.3    Oku, N.4    Yamamoto, T.5    Osaki, T.6
  • 33
    • 0035145591 scopus 로고    scopus 로고
    • Kip1 regulate cell cycle reentry after hypoxic stress but are not necessary for hypoxia-induced arrest
    • DOI 10.1128/MCB.21.4.1196-1206.2001
    • Green SL, Freiberg RA and Giaccia AJ: p21(Cip1) and p27(Kip1) regulate cell cycle reentry after hypoxic stress but are not necessary for hypoxia-induced arrest. Mol Cell Biol 21: 1196-1206, 2001. (Pubitemid 32114968)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.4 , pp. 1196-1206
    • Green, S.L.1    Freiberg, R.A.2    Giaccia, A.J.3
  • 34
    • 1242271198 scopus 로고    scopus 로고
    • Topoisomerase I-Mediated Inhibition of Hypoxia-Inducible Factor 1: Mechanism and Therapeutic Implications
    • DOI 10.1158/0008-5472.CAN-03-3139
    • Rapisarda A, Uranchimeg B, Sordet O, Pommier Y, Shoemaker RH and Melillo G: Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications. Cancer Res 64: 1475-1482, 2004. (Pubitemid 38235619)
    • (2004) Cancer Research , vol.64 , Issue.4 , pp. 1475-1482
    • Rapisarda, A.1    Uranchimeg, B.2    Sordet, O.3    Pommier, Y.4    Shoemaker, R.H.5    Melillo, G.6
  • 35
    • 13744263516 scopus 로고    scopus 로고
    • Anti-angiogenic effects of SN38 (active metabolite of irinotecan): Inhibition of hypoxia-inducible factor 1 alpha HIF-1alpha/vascular endothelial growth factor (VEGF) expression of glioma and growth of endothelial cells
    • DOI 10.1007/s00432-004-0642-z
    • Kamiyama H, Takano S, Tsuboi K and Matsumura A: Anti-angiogenic effects of SN38 (active metabolite of irinotecan): inhibition of hypoxia-inducible factor 1 alpha (HIF-1alpha)/vascular endothelial growth factor (VEGF) expression of glioma and growth of endothelial cells. J Cancer Res Clin Oncol 131: 205-213, 2005. (Pubitemid 40238935)
    • (2005) Journal of Cancer Research and Clinical Oncology , vol.131 , Issue.4 , pp. 205-213
    • Kamiyama, H.1    Takano, S.2    Tsuboi, K.3    Matsumura, A.4
  • 36
    • 77956060677 scopus 로고    scopus 로고
    • Metronomic treatment of malignant glioma xenografts with irinotecan (CPT-11) inhibits angiogenesis and tumor growth
    • Takano S, Kamiyama H, Mashiko R, Osuka S, Ishikawa E and Matsumura A: Metronomic treatment of malignant glioma xenografts with irinotecan (CPT-11) inhibits angiogenesis and tumor growth. J Neurooncol 99: 177-185, 2010.
    • (2010) J Neurooncol , vol.99 , pp. 177-185
    • Takano, S.1    Kamiyama, H.2    Mashiko, R.3    Osuka, S.4    Ishikawa, E.5    Matsumura, A.6
  • 37
    • 63149114714 scopus 로고    scopus 로고
    • Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target of rapamycin/hypoxia-inducible factor-1alpha axis
    • Pencreach E, Guerin E, Nicolet C, Lelong-Rebel I, Voegeli AC, Oudet P, Larsen AK, Gaub MP and Guenot D: Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target of rapamycin/hypoxia-inducible factor-1alpha axis. Clin Cancer Res 15: 1297-1307, 2009.
    • (2009) Clin Cancer Res , vol.15 , pp. 1297-1307
    • Pencreach, E.1    Guerin, E.2    Nicolet, C.3    Lelong-Rebel, I.4    Voegeli, A.C.5    Oudet, P.6    Larsen, A.K.7    Gaub, M.P.8    Guenot, D.9
  • 38
    • 0025996996 scopus 로고
    • Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11
    • Kawato Y, Aonuma M, Hirota Y, Kuga H and Sato K: Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11. Cancer Res 51: 4187-4191, 1991.
    • (1991) Cancer Res , vol.51 , pp. 4187-4191
    • Kawato, Y.1    Aonuma, M.2    Hirota, Y.3    Kuga, H.4    Sato, K.5
  • 39
    • 0031046059 scopus 로고    scopus 로고
    • CPT-11 in human colon-cancer cell lines and xenograft: Characterization of cellular sensitivity determinants
    • DOI 10.1002/(SICI)1097-0215(19970127)70:3<335::AID-IJC15>3.0.CO;2-E
    • Jansen WJ, Zwart B, Hulscher ST, Giaccone G, Pinedo HM and Boven E: CPT-11 in human colon cancer cell lines and xenografts: characterization of cellular sensitivity determinants. Int J Cancer 70: 335-340, 1997. (Pubitemid 27099604)
    • (1997) International Journal of Cancer , vol.70 , Issue.3 , pp. 335-340
    • Jansen, W.J.M.1    Zwart, B.2    Hulscher, S.T.M.3    Giaccone, G.4    Pinedo, H.M.5    Boven, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.