MUC1 contributes to BPDE-induced human bronchial epithelial cell transformation through facilitating EGFR activation

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Xu, Xiuling ^a   Bai, Lang ^a   Chen, Wenshu ^a   Padilla, Mabel T ^a   Liu, Yushi ^a   Kim, Kwang Chul ^b   Belinsky, Steven A ^a   Lin, Yong ^a  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MUCIN 1; PROTEIN KINASE B; BENZO[A]PYRENE 7,8 DIHYDRODIOL 9,10 OXIDE; MUC1 PROTEIN, HUMAN;

ARTICLE; CELL SURVIVAL; CELL TRANSFORMATION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME INACTIVATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; LUNG CARCINOGENESIS; MALIGNANT TRANSFORMATION; PROTEIN FUNCTION; RECEPTOR UPREGULATION; ANIMAL; BRONCHUS; CELL LINE; CYTOLOGY; DRUG EFFECT; METABOLISM; PHYSIOLOGY;

ANIMALIA;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANIMALS; BRONCHI; CELL LINE, TRANSFORMED; ENZYME ACTIVATION; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; MUCIN-1; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 84863348147     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033846     Document Type: Article

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