-
1
-
-
67651217289
-
-
Global cancer rates could increase by 50% to 15 million by 2020. http://www.who.int/mediacentre/news/releases/2003/pr27/en/.
-
Global cancer rates could increase by 50% to 15 million by 2020. http://www.who.int/mediacentre/news/releases/2003/pr27/en/.
-
-
-
-
2
-
-
67651218361
-
-
Ries LAG, Melbert D, Krapcho M, Stinchcomb DG, Howlader N, Horner MJ, et al., editors. SEER Cancer Statistics Review, 1975-2005, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2005/. Center for Cancer Control and Information Services, National Cancer Center, Japan http://ganjoho.ncc.go.jp/professional/statistics/statistics.html.
-
Ries LAG, Melbert D, Krapcho M, Stinchcomb DG, Howlader N, Horner MJ, et al., editors. SEER Cancer Statistics Review, 1975-2005, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2005/. Center for Cancer Control and Information Services, National Cancer Center, Japan http://ganjoho.ncc.go.jp/professional/statistics/statistics.html).
-
-
-
-
3
-
-
0026635436
-
Inhibition of N-nitrosodiethylamine- and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced tumorigenesis in A/J mice by green tea and black tea
-
Wang Z.Y., Hong J.Y., Huang M.T., Reuhl K.R., Conney A.H., and Yang C.S. Inhibition of N-nitrosodiethylamine- and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced tumorigenesis in A/J mice by green tea and black tea. Cancer Res 52 (1992) 1943-1947
-
(1992)
Cancer Res
, vol.52
, pp. 1943-1947
-
-
Wang, Z.Y.1
Hong, J.Y.2
Huang, M.T.3
Reuhl, K.R.4
Conney, A.H.5
Yang, C.S.6
-
4
-
-
0034019659
-
(-)-Epigallocatechin gallate can prevent cisplatin-induced lung tumorigenesis in A/J mice
-
Mimoto J., Kiura K., Matsuo K., Yoshino T., Takata I., Ueoka H., et al. (-)-Epigallocatechin gallate can prevent cisplatin-induced lung tumorigenesis in A/J mice. Carcinogenesis 21 (2000) 915-919
-
(2000)
Carcinogenesis
, vol.21
, pp. 915-919
-
-
Mimoto, J.1
Kiura, K.2
Matsuo, K.3
Yoshino, T.4
Takata, I.5
Ueoka, H.6
-
5
-
-
0032403140
-
Prevention of NNK-induced lung tumorigenesis in A/J mice by acetylsalicylic acid and NS-398
-
Rioux N., and Castonguay A. Prevention of NNK-induced lung tumorigenesis in A/J mice by acetylsalicylic acid and NS-398. Cancer Res 58 (1998) 5354-5360
-
(1998)
Cancer Res
, vol.58
, pp. 5354-5360
-
-
Rioux, N.1
Castonguay, A.2
-
6
-
-
0014082616
-
Experimental cancer of the lung. Inhibition by vitamin A of the induction of tracheobronchial squamous metaplasia and squamous cell tumors
-
Saffiotti U., Montesano R., Sellakumar A.R., and Borg S.A. Experimental cancer of the lung. Inhibition by vitamin A of the induction of tracheobronchial squamous metaplasia and squamous cell tumors. Cancer 20 (1967) 857-864
-
(1967)
Cancer
, vol.20
, pp. 857-864
-
-
Saffiotti, U.1
Montesano, R.2
Sellakumar, A.R.3
Borg, S.A.4
-
7
-
-
0021364617
-
Relation of serum vitamins A and E and carotenoids to the risk of cancer
-
Willett W.C., Polk B.F., Underwood B.A., Stampfer M.J., Pressel S., Rosner B., et al. Relation of serum vitamins A and E and carotenoids to the risk of cancer. N Engl J Med 310 (1984) 430-434
-
(1984)
N Engl J Med
, vol.310
, pp. 430-434
-
-
Willett, W.C.1
Polk, B.F.2
Underwood, B.A.3
Stampfer, M.J.4
Pressel, S.5
Rosner, B.6
-
8
-
-
0010607277
-
The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers
-
The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group
-
The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med 330 (1994) 1029-1035
-
(1994)
N Engl J Med
, vol.330
, pp. 1029-1035
-
-
-
9
-
-
0036362221
-
Epidermal growth factor receptor dependence in human tumors: more than just expression?
-
Arteaga C.L. Epidermal growth factor receptor dependence in human tumors: more than just expression?. Oncologist 7 Suppl 4 (2002) 31
-
(2002)
Oncologist
, vol.7
, Issue.SUPPL. 4
, pp. 31
-
-
Arteaga, C.L.1
-
10
-
-
0036645063
-
Novel targets for lung cancer therapy. Part I
-
Dy G.K., and Adjei A.A. Novel targets for lung cancer therapy. Part I. J Clin Oncol 20 (2002) 2881-2894
-
(2002)
J Clin Oncol
, vol.20
, pp. 2881-2894
-
-
Dy, G.K.1
Adjei, A.A.2
-
11
-
-
0010432660
-
Uracil mustard: a potent inducer of lung tumors in mice
-
Abell C.W., Falk H.L., Shimkin M.B., Weisburger E.K., Weisburger J.H., and Gubareff N. Uracil mustard: a potent inducer of lung tumors in mice. Science 147 (1965) 1443-1445
-
(1965)
Science
, vol.147
, pp. 1443-1445
-
-
Abell, C.W.1
Falk, H.L.2
Shimkin, M.B.3
Weisburger, E.K.4
Weisburger, J.H.5
Gubareff, N.6
-
12
-
-
0028566646
-
Lung tumor induction in A/J mice by the tobacco smoke carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene: a potentially useful model for evaluation of chemopreventive agents
-
Hecht S.S., Isaacs S., and Trushin N. Lung tumor induction in A/J mice by the tobacco smoke carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene: a potentially useful model for evaluation of chemopreventive agents. Carcinogenesis 15 (1994) 2721-2725
-
(1994)
Carcinogenesis
, vol.15
, pp. 2721-2725
-
-
Hecht, S.S.1
Isaacs, S.2
Trushin, N.3
-
13
-
-
0029956857
-
Inhibited transformation of immortalized human bronchial epithelial cells by retinoic acid is linked to cyclin E down-regulation
-
Langenfeld J., Lonardo F., Kiyokawa H., Passalaris T., Ahn M.J., Rusch V., et al. Inhibited transformation of immortalized human bronchial epithelial cells by retinoic acid is linked to cyclin E down-regulation. Oncogene 13 (1996) 1983-1990
-
(1996)
Oncogene
, vol.13
, pp. 1983-1990
-
-
Langenfeld, J.1
Lonardo, F.2
Kiyokawa, H.3
Passalaris, T.4
Ahn, M.J.5
Rusch, V.6
-
14
-
-
0027159063
-
Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung
-
Rusch V., Baselga J., Cordon-Cardo C., Orazem J., Zaman M., Hoda S., et al. Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung. Cancer Res 53 suppl. 10 (1993) 2379-2385
-
(1993)
Cancer Res
, vol.53
, Issue.SUPPL. 10
, pp. 2379-2385
-
-
Rusch, V.1
Baselga, J.2
Cordon-Cardo, C.3
Orazem, J.4
Zaman, M.5
Hoda, S.6
-
15
-
-
0036152814
-
Evidence for the epidermal growth factor receptor as a target for lung cancer prevention
-
Lonardo F., Dragnev K.H., Freemantle S.J., Ma Y., Memoli N., Sekula D., et al. Evidence for the epidermal growth factor receptor as a target for lung cancer prevention. Clin Cancer Res 8 (2002) 54-60
-
(2002)
Clin Cancer Res
, vol.8
, pp. 54-60
-
-
Lonardo, F.1
Dragnev, K.H.2
Freemantle, S.J.3
Ma, Y.4
Memoli, N.5
Sekula, D.6
-
16
-
-
0036139727
-
Pharmacodynamic studies of the epidermal growth factor receptor inhibitor ZD1839 in skin from cancer patients: histopathologic and molecular consequences of receptor inhibition
-
Albanell J., Rojo F., Averbuch S., Feyereislova A., Mascaro J.M., Herbst R., et al. Pharmacodynamic studies of the epidermal growth factor receptor inhibitor ZD1839 in skin from cancer patients: histopathologic and molecular consequences of receptor inhibition. J Clin Oncol 20 (2002) 110
-
(2002)
J Clin Oncol
, vol.20
, pp. 110
-
-
Albanell, J.1
Rojo, F.2
Averbuch, S.3
Feyereislova, A.4
Mascaro, J.M.5
Herbst, R.6
-
17
-
-
67651215159
-
-
Gefitinib Iressa 250 mg Tablet No. 28 New Drug Approval Package (NAP) Japan Pharmaceutical Education Center, Yakuji Nipposha, Tokyo, Japan; 2003.
-
Gefitinib Iressa 250 mg Tablet No. 28 New Drug Approval Package (NAP) Japan Pharmaceutical Education Center, Yakuji Nipposha, Tokyo, Japan; 2003.
-
-
-
-
18
-
-
0019846242
-
Mutagenicity, tumorigenicity, and electrophilic reactivity of the stereoisomeric platinum(II) complexes of 1,2-diaminocyclohexane
-
Leopold W.R., Batzinger R.P., Miller E.C., Miller J.A., and Earhart R.H. Mutagenicity, tumorigenicity, and electrophilic reactivity of the stereoisomeric platinum(II) complexes of 1,2-diaminocyclohexane. Cancer Res 41 11 Pt 1 (1981) 4368-4377
-
(1981)
Cancer Res
, vol.41
, Issue.11 PART 1
, pp. 4368-4377
-
-
Leopold, W.R.1
Batzinger, R.P.2
Miller, E.C.3
Miller, J.A.4
Earhart, R.H.5
-
19
-
-
34548477938
-
Point mutation of K-ras gene in cisplatin-induced lung tumours in A/J mice
-
Hisamoto A., Kondo E., Kiura K., Okada T., Hosokawa S., Mimoto J., et al. Point mutation of K-ras gene in cisplatin-induced lung tumours in A/J mice. Lung Cancer 58 (2007) 15-20
-
(2007)
Lung Cancer
, vol.58
, pp. 15-20
-
-
Hisamoto, A.1
Kondo, E.2
Kiura, K.3
Okada, T.4
Hosokawa, S.5
Mimoto, J.6
-
20
-
-
0024437222
-
Relationship between the formation of promutagenic adducts and the activation of the K-ras protooncogene in lung tumors from A/J mice treated with nitrosamines
-
Belinsky S.A., Devereux T.R., Maronpot R.R., Stoner G.D., and Anderson M.W. Relationship between the formation of promutagenic adducts and the activation of the K-ras protooncogene in lung tumors from A/J mice treated with nitrosamines. Cancer Res 49 (1989) 5305-5311
-
(1989)
Cancer Res
, vol.49
, pp. 5305-5311
-
-
Belinsky, S.A.1
Devereux, T.R.2
Maronpot, R.R.3
Stoner, G.D.4
Anderson, M.W.5
-
21
-
-
2342624080
-
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
-
Paez J.G., Jänne P.A., Lee J.C., Tracy S., Greulich H., Gabriel S., et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304 (2004) 1497-1500
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Jänne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
-
22
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch T.J., Bell D.W., Sordella R., Gurubhagavatula S., Okimoto R.A., Brannigan B.W., et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350 (2004) 2129-2139
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
-
23
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W., Miller V., Zakowski M., Doherty J., Politi K., Sarkaria I., et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 101 (2004) 13306-13311
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
Doherty, J.4
Politi, K.5
Sarkaria, I.6
-
24
-
-
10844231985
-
Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications
-
Kosaka T., Yatabe Y., Endoh H., Kuwano H., Takahashi T., and Mitsudomi T. Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications. Cancer Res 64 (2004) 8919-8923
-
(2004)
Cancer Res
, vol.64
, pp. 8919-8923
-
-
Kosaka, T.1
Yatabe, Y.2
Endoh, H.3
Kuwano, H.4
Takahashi, T.5
Mitsudomi, T.6
-
25
-
-
38949200943
-
Occurrence of mutations in the epidermal growth factor receptor gene in X-ray-induced rat lung tumors
-
Kitahashi T., Takahashi M., Yamada Y., Oghiso Y., Yokohira M., Imaida K., et al. Occurrence of mutations in the epidermal growth factor receptor gene in X-ray-induced rat lung tumors. Cancer Sci 99 (2008) 241-245
-
(2008)
Cancer Sci
, vol.99
, pp. 241-245
-
-
Kitahashi, T.1
Takahashi, M.2
Yamada, Y.3
Oghiso, Y.4
Yokohira, M.5
Imaida, K.6
-
26
-
-
33846702126
-
Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation
-
Uchida A., Hirano S., Kitao H., Ogino A., Rai K., Toyooka S., et al. Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation. Cancer Sci 98 (2007) 357-363
-
(2007)
Cancer Sci
, vol.98
, pp. 357-363
-
-
Uchida, A.1
Hirano, S.2
Kitao, H.3
Ogino, A.4
Rai, K.5
Toyooka, S.6
-
27
-
-
33846274624
-
Effect of an epidermal growth factor receptor inhibitor in mouse models of lung cancer
-
Yan Y., Lu Y., Wang M., Vikis H., Yao R., Wang Y., et al. Effect of an epidermal growth factor receptor inhibitor in mouse models of lung cancer. Mol Cancer Res 4 (2006) 971-981
-
(2006)
Mol Cancer Res
, vol.4
, pp. 971-981
-
-
Yan, Y.1
Lu, Y.2
Wang, M.3
Vikis, H.4
Yao, R.5
Wang, Y.6
-
28
-
-
0041887251
-
Epidermal growth factor receptor tyrosine kinase inhibition augments a murine model of pulmonary fibrosis
-
Suzuki H., Aoshiba K., Yokohori N., and Nagai A. Epidermal growth factor receptor tyrosine kinase inhibition augments a murine model of pulmonary fibrosis. Cancer Res 63 (2003) 5054-5059
-
(2003)
Cancer Res
, vol.63
, pp. 5054-5059
-
-
Suzuki, H.1
Aoshiba, K.2
Yokohori, N.3
Nagai, A.4
-
29
-
-
33748304169
-
Gefitinib prevents bleomycin-induced lung fibrosis in mice
-
Ishii Y., Fujimoto S., and Fukuda T. Gefitinib prevents bleomycin-induced lung fibrosis in mice. Am J Respir Crit Care Med 174 (2006) 550-556
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 550-556
-
-
Ishii, Y.1
Fujimoto, S.2
Fukuda, T.3
-
30
-
-
67651237922
-
Lung carcinogenesis induced by NNK in Ogg1 knockout mice
-
Igarashi M, Yoshida M, Watanabe M, Abe M, Sugano S, Nakae D. Lung carcinogenesis induced by NNK in Ogg1 knockout mice. Proceedings of the 66th Annual Meeting of the Japanese Cancer Association. 2007.
-
(2007)
Proceedings of the 66th Annual Meeting of the Japanese Cancer Association
-
-
Igarashi, M.1
Yoshida, M.2
Watanabe, M.3
Abe, M.4
Sugano, S.5
Nakae, D.6
|