A highly conserved cytoplasmic cysteine residue in the α4 nicotinic acetylcholine receptor is palmitoylated and regulates protein expression

Journal of Biological Chemistry

Volumn 287, Issue 27, 2012, Pages 23119-23127

  Amici, Stephanie A ^a   McKay, Susan B ^a   Wells, Gregg B ^b   Robson, Jordan I ^a   Nasir, Muhammad ^a   Ponath, Gerald ^a   Anand, Rene ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b TEXAS A M COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4-LEVEL; CELL SURFACE EXPRESSION; CELL SURFACE PROTEINS; CELL SURFACES; CYSTEINE RESIDUES; CYTOPLASMIC LOOPS; ENZYME-LINKED IMMUNOASSAYS; EPIBATIDINE; FUNCTIONAL ACTIVITIES; HIGH AFFINITY BINDING; INTRACELLULAR LOOP; MEMBRANE RECEPTORS; METABOLIC LABELING; NICOTINIC ACETYLCHOLINE RECEPTORS; NICOTINIC ACETYLCHOLINE RECEPTORS (NACHR); PALMITOYLATION; POST-TRANSLATIONAL MODIFICATIONS; PROTEIN EXPRESSIONS; REGULATORY FACTORS; SITE DIRECTED MUTAGENESIS; SURFACE EXPRESSION; TOTAL PROTEIN; TRANS-MEMBRANE DOMAINS; WESTERN BLOTTING; WILD TYPES;

ACTIVATION ANALYSIS; ACYLATION; CELL MEMBRANES; ENZYME ACTIVITY; PROTEINS;

AMINO ACIDS;

CYSTEINE; EPIBATIDINE; MEMBRANE RECEPTOR; NICOTINIC RECEPTOR ALPHA4; TRITIUM;

ARTICLE; BINDING AFFINITY; CALCIUM BINDING; CALCIUM CELL LEVEL; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; EMBRYO; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE LOCATION; GENETIC CONSERVATION; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; INTRACELLULAR TRANSPORT; NERVE CELL; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN PROCESSING; RESIDUE ANALYSIS; SITE DIRECTED MUTAGENESIS; WILD TYPE;

ANIMALS; CALCIUM; COCULTURE TECHNIQUES; CYSTEINE; CYTOPLASM; HEK293 CELLS; HIPPOCAMPUS; HUMANS; LIPOYLATION; NEURONS; PALMITATES; PRIMARY CELL CULTURE; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RATS; RECEPTORS, CELL SURFACE; RECEPTORS, NICOTINIC; TRITIUM;

EID: 84863314479     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.328294     Document Type: Article

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