Interaction analysis between genetic polymorphisms and pharmacodynamic effect in patients treated with adjunctive cilostazol to dual antiplatelet therapy: Results of the ACCEL-TRIPLE (Accelerated Platelet Inhibition by Triple Antiplatelet Therapy According to Gene Polymorphism) study

British Journal of Clinical Pharmacology

Volumn 73, Issue 4, 2012, Pages 629-640

  Kim, In Suk ^a   Jeong, Young Hoon ^b,c   Park, Yongwhi ^b   Yoon, Seong Eun ^b   Kwon, Tae Jung ^b   Park, Jeong Rang ^b   Hwang, Seok Jae ^b   Koh, Eun Ha ^b   Kwak, Choong Hwan ^b   Hwang, Jin Yong ^b   Kim, Sunjoo ^b  

^a Pusan National University School of Medicine   (South Korea)

^b Gyeongsang National University   (South Korea)

^c SINAI CENTER FOR THROMBOSIS RESEARCH   (United States)

Author keywords

Cilostazol; Clopidogrel; Genetic polymorphism; High on treatment platelet reactivity; Platelet

Indexed keywords

CILOSTAZOL; CYTOCHROME P450 2C19; CYTOCHROME P450 3A5; MULTIDRUG RESISTANCE PROTEIN 1;

ADULT; AGED; ALLELE; ARTICLE; DRUG EFFECT; FEMALE; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; LOSS OF FUNCTION MUTATION; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PERCUTANEOUS CORONARY INTERVENTION; PREDICTION; PREVALENCE; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION;

AGED; ARYL HYDROCARBON HYDROXYLASES; ASPIRIN; COHORT STUDIES; CYTOCHROME P-450 CYP3A; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; MALE; MIDDLE AGED; P-GLYCOPROTEIN; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; POLYMORPHISM, GENETIC; REGRESSION ANALYSIS; TETRAZOLES; TICLOPIDINE;

EID: 84863294046     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2011.04131.x     Document Type: Article

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