메뉴 건너뛰기




Volumn 50, Issue 4, 2012, Pages 506-515

The herbal composition GGEx18 from Laminaria japonica, Rheum palmatum, and Ephedra sinica reduces obesity via skeletal muscle AMPK and PPARα

Author keywords

AMPK; C2C12; Fatty acid oxidation; GGEx18; Obesity; PPAR ; Skeletal muscle

Indexed keywords

AMP ACTIVATED PROTEIN KINASE ALPHA 1; AMP ACTIVATED PROTEIN KINASE ALPHA 2; ANTIOBESITY AGENT; CARNITINE PALMITOYLTRANSFERASE I; GYEONGSHINGANGJEEHWAN 18; HERBACEOUS AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE; MESSENGER RNA; OXIDOREDUCTASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 3; VERY LONG CHAIN ACYL COENZYME A DEHYDROGENASE;

EID: 84863284753     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2011.618502     Document Type: Article
Times cited : (15)

References (35)
  • 1
    • 79960556876 scopus 로고    scopus 로고
    • Reduced leptin secretion by fucoidan-added kochujang and anti-adipogenic effect of fucoidan in mouse 3T3-l1 adipocytes
    • Ahn IS, Do MS, Choi BH, Kong CS, Kim SO, Han MS, Park KY. (2006). Reduced leptin secretion by fucoidan-added Kochujang and anti-adipogenic effect of fucoidan in mouse 3T3-L1 adipocytes. J Food Sci 11:31-35.
    • (2006) J Food Sci , vol.11 , pp. 31-35
    • Ahn, I.S.1    Do, M.S.2    Choi, B.H.3    Kong, C.S.4    Kim, S.O.5    Han, M.S.6    Park, K.Y.7
  • 2
    • 0032489437 scopus 로고    scopus 로고
    • Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor α (PPARα)
    • DOI 10.1074/jbc.273.10.5678
    • Aoyama T, Peters JM, iritani N, Nakajima T, Furihata K, Hashimoto T, Gonzalez FJ. (1998). Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha). J Biol Chem, 273, 5678-5684. (Pubitemid 28124039)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.10 , pp. 5678-5684
    • Aoyama, T.1    Peters, J.M.2    Iritani, N.3    Nakajima, T.4    Furihata, K.5    Hashimoto, T.6    Gonzalez, F.J.7
  • 4
    • 0035098157 scopus 로고    scopus 로고
    • An herbal supplement containing Ma Huang-Guarana for weight loss: A randomized, double-blind trial
    • DOI 10.1038/sj.ijo.0801539
    • Boozer CN, Nasser JA, Heymsfeld SB, Wang V, Chen G, Solomon JL. (2001). An herbal supplement containing Ma Huang-Guarana for weight loss: A randomized, double-blind trial. Int J Obes Relat Metab Disord, 25, 316-324. (Pubitemid 32209805)
    • (2001) International Journal of Obesity , vol.25 , Issue.3 , pp. 316-324
    • Boozer, C.N.1    Nasser, J.A.2    Heymsfield, S.B.3    Wang, V.4    Chen, G.5    Solomon, J.L.6
  • 5
    • 0347318052 scopus 로고    scopus 로고
    • The AMP-activated protein kinase cascade - A unifying system for energy control
    • DOI 10.1016/j.tibs.2003.11.005
    • Carling D. (2004). The AMP-activated protein kinase cascade-a unifying system for energy control. Trends Biochem Sci, 29, 18-24. (Pubitemid 38068476)
    • (2004) Trends in Biochemical Sciences , vol.29 , Issue.1 , pp. 18-24
    • Carling, D.1
  • 6
    • 0028960787 scopus 로고
    • Skeletal muscle utilization of free fatty acids in women with visceral obesity
    • Colberg SR, Simoneau JA, Taete FL, Kelley DE. (1995). Skeletal muscle utilization of free fatty acids in women with visceral obesity. J Clin Invest, 95, 1846-1853.
    • (1995) J Clin Invest , vol.95 , pp. 1846-1853
    • Colberg, S.R.1    Simoneau, J.A.2    Taete, F.L.3    Kelley, D.E.4
  • 7
    • 33745822416 scopus 로고    scopus 로고
    • Metformin counters the insulin-induced suppression of fatty acid oxidation and stimulation of triacylglycerol storage in rodent skeletal muscle
    • DOI 10.1152/ajpendo.00272.2005
    • Collier CA, Bruce CR, Smith AC, Lopaschuk G, Dyck DJ. (2006). Metformin counters the insulin-induced suppression of fatty acid oxidation and stimulation of triacylglycerol storage in rodent skeletal muscle. Am J Physiol Endocrinol Metab, 291, E182-E189. (Pubitemid 44035324)
    • (2006) American Journal of Physiology - Endocrinology and Metabolism , vol.291 , Issue.1
    • Collier, C.A.1    Bruce, C.R.2    Smith, A.C.3    Lopaschuk, G.4    Dyck, D.J.5
  • 8
    • 57049132274 scopus 로고    scopus 로고
    • Safety of ephedra and related anorexic medications
    • Fleming RM. (2008). Safety of ephedra and related anorexic medications. Expert Opin Drug Saf, 7, 749-759.
    • (2008) Expert Opin Drug Saf , vol.7 , pp. 749-759
    • Fleming, R.M.1
  • 9
    • 51449094922 scopus 로고    scopus 로고
    • Effects of an amp-activated protein kinase inhibitor, compound c, on adipogenic diferentiation of 3T3-l1 cells
    • Gao Y, Zhou Y, Xu A, Wu D. (2008). Effects of an AMP-activated protein kinase inhibitor, compound C, on adipogenic diferentiation of 3T3-L1 cells. Biol Pharm Bull, 31, 1716-1722.
    • (2008) Biol Pharm Bull , vol.31 , pp. 1716-1722
    • Gao, Y.1    Zhou, Y.2    Xu, A.3    Wu, D.4
  • 10
    • 0034700454 scopus 로고    scopus 로고
    • Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids
    • DOI 10.1056/NEJM200012213432502
    • Haller CA, Benowitz NL. (2000). Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids. N Engl J Med, 343, 1833-1838. (Pubitemid 32104128)
    • (2000) New England Journal of Medicine , vol.343 , Issue.25 , pp. 1833-1838
    • Haller, C.A.1    Benowitz, N.L.2
  • 11
    • 50049091255 scopus 로고    scopus 로고
    • Ampk: A key regulator of energy balance in the single cell and the whole organism
    • Hardie DG. (2008). AMPK: A key regulator of energy balance in the single cell and the whole organism. Int J Obes (Lond), 32 Suppl 4, S7-12.
    • (2008) Int J Obes (Lond) , vol.32 , Issue.SUPPL. 4
    • Hardie, D.G.1
  • 12
    • 0031717105 scopus 로고    scopus 로고
    • The AMP-activated/SNF1 protein kinase subfamily: Metabolic sensors of the eukaryotic cell?
    • DOI 10.1146/annurev.biochem.67.1.821
    • Hardie DG, Carling D, Carlson M. (1998). The AMP-activated/SNF1 protein kinase subfamily: Metabolic sensors of the eukaryotic cell? Annu Rev Biochem, 67, 821-855. (Pubitemid 28411146)
    • (1998) Annual Review of Biochemistry , vol.67 , pp. 821-855
    • Hardie, D.G.1    Carling, D.2    Carlson, M.3
  • 13
    • 33745225026 scopus 로고    scopus 로고
    • AMP-activated protein kinase - Development of the energy sensor concept
    • DOI 10.1113/jphysiol.2006.108944
    • Hardie DG, Hawley SA, Scott JW. (2006). AMP-activated protein kinase-development of the energy sensor concept. J Physiol (Lond), 574, 7-15. (Pubitemid 43905792)
    • (2006) Journal of Physiology , vol.574 , Issue.1 , pp. 7-15
    • Hardie, D.G.1    Hawley, S.A.2    Scott, J.W.3
  • 14
    • 77950241905 scopus 로고    scopus 로고
    • Hypolipidemic effect of fucoidan from Laminaria japonica in hyperlipidemic rats
    • Huang L, Wen K, Gao X, Liu Y. (2010). Hypolipidemic effect of fucoidan from Laminaria japonica in hyperlipidemic rats. Pharm Biol, 48, 422-426.
    • (2010) Pharm Biol , vol.48 , pp. 422-426
    • Huang, L.1    Wen, K.2    Gao, X.3    Liu, Y.4
  • 17
    • 0032553545 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor controls the hepatic CYP4A induction adaptive response to starvation and diabetes
    • DOI 10.1074/jbc.273.47.31581
    • Kroetz DL, Yook P, Costet P, Bianchi P, Pineau T. (1998). Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes. J Biol Chem, 273, 31581-31589. (Pubitemid 28533182)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.47 , pp. 31581-31589
    • Kroetz, D.L.1    Yook, P.2    Costet, P.3    Bianchi, P.4    Pineau, T.5
  • 20
    • 79953220498 scopus 로고    scopus 로고
    • Reduction of lipid accumulation in HepG2 cells by luteolin is associated with activation of AMPK and mitigation of oxidative stress
    • Liu JF, Ma Y, Wang Y, Du ZY, Shen JK, Peng HL. (2011). Reduction of lipid accumulation in HepG2 cells by luteolin is associated with activation of AMPK and mitigation of oxidative stress. Phytother Res, 25, 588-596.
    • (2011) Phytother Res , vol.25 , pp. 588-596
    • Liu, J.F.1    Ma, Y.2    Wang, Y.3    Du, Z.Y.4    Shen, J.K.5    Peng, H.L.6
  • 21
    • 33745815985 scopus 로고    scopus 로고
    • AMP-activated protein kinase signaling in metabolic regulation
    • DOI 10.1172/JCI29044
    • Long YC, Zierath JR. (2006). AMP-activated protein kinase signaling in metabolic regulation. J Clin Invest, 116, 1776-1783. (Pubitemid 44033297)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 1776-1783
    • Yun, C.L.1    Zierath, J.R.2
  • 22
    • 33646512418 scopus 로고    scopus 로고
    • Roles of skeletal muscle and peroxisome proliferator-activated receptors in the development and treatment of obesity
    • López-Soriano J, Chiellini C, Mafei M, Grimaldi PA, Argilés JM. (2006). Roles of skeletal muscle and peroxisome proliferator-activated receptors in the development and treatment of obesity. Endocr Rev, 27, 318-329.
    • (2006) Endocr Rev , vol.27 , pp. 318-329
    • López-Soriano, J.1    Chiellini, C.2    Mafei, M.3    Grimaldi, P.A.4    Argilés, J.M.5
  • 24
    • 0032752951 scopus 로고    scopus 로고
    • Markers of capacity to utilize fatty acids in human skeletal muscle: Relation to insulin resistance and obesity and effects of weight loss
    • Simoneau JA, Veerkamp JH, Turcotte LP, Kelley DE. (1999). Markers of capacity to utilize fatty acids in human skeletal muscle: relation to insulin resistance and obesity and effects of weight loss. FASEB J, 13, 2051-2060. (Pubitemid 29517635)
    • (1999) FASEB Journal , vol.13 , Issue.14 , pp. 2051-2060
    • Simoneau, J.-A.1    Veerkamp, J.H.2    Turcotte, L.P.3    Kelley, D.E.4
  • 25
    • 34250182374 scopus 로고    scopus 로고
    • Leptin stimulates fatty acid oxidation and peroxisome proliferator- activated receptor α gene expression in mouse C2C12 myoblasts by changing the subcellular localization of the α2 form of amp-activated protein kinase
    • DOI 10.1128/MCB.02222-06
    • Suzuki A, Okamoto S, Lee S, Saito K, Shiuchi T, Minokoshi Y. (2007). Leptin stimulates fatty acid oxidation and peroxisome proliferator-activated receptor alpha gene expression in mouse C2C12 myoblasts by changing the subcellular localization of the alpha2 form of AMP-activated protein kinase. Mol Cell Biol, 27, 4317-4327. (Pubitemid 46906556)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.12 , pp. 4317-4327
    • Suzuki, A.1    Okamoto, S.2    Lee, S.3    Saito, K.4    Shiuchi, T.5    Minokoshi, Y.6
  • 26
    • 33745204479 scopus 로고    scopus 로고
    • AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues
    • DOI 10.1113/jphysiol.2006.113217
    • Xue B, Kahn BB. (2006). AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues. J Physiol (Lond), 574, 73-83. (Pubitemid 43905798)
    • (2006) Journal of Physiology , vol.574 , Issue.1 , pp. 73-83
    • Xue, B.1    Kahn, B.B.2
  • 27
    • 75849147916 scopus 로고    scopus 로고
    • Anti-diabetic effects of emodin involved in the activation of ppargamma on high-fat diet-fed and low dose of streptozotocin-induced diabetic mice
    • Xue J, Ding W, Liu Y. (2010). Anti-diabetic effects of emodin involved in the activation of PPARgamma on high-fat diet-fed and low dose of streptozotocin-induced diabetic mice. Fitoterapia, 81, 173-177.
    • (2010) Fitoterapia , vol.81 , pp. 173-177
    • Xue, J.1    Ding, W.2    Liu, Y.3
  • 28
    • 0000174206 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptor α-induced transactivation by the nuclear orphan receptor TAK1/TR4
    • DOI 10.1074/jbc.273.18.10948
    • Yan ZH, Karam WG, Staudinger JL, Medvedev A, Ghanayem Bi, Jetten AM. (1998). Regulation of peroxisome proliferator-activated receptor alpha-induced transactivation by the nuclear orphan receptor TAK1/TR4. J Biol Chem, 273, 10948-10957. (Pubitemid 28204934)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.18 , pp. 10948-10957
    • Yan, Z.H.1    Karam, W.G.2    Staudinger, J.L.3    Medvedev, A.4    Ghanayem, B.I.5    Jetten, A.M.6
  • 29
    • 67651102871 scopus 로고    scopus 로고
    • The role of pparalpha in lipid metabolism and obesity: Focusing on the effects of estrogen on pparalpha actions
    • Yoon M. (2009). The role of PPARalpha in lipid metabolism and obesity: Focusing on the effects of estrogen on PPARalpha actions. Pharmacol Res, 60, 151-159.
    • (2009) Pharmacol Res , vol.60 , pp. 151-159
    • Yoon, M.1
  • 30
    • 77956859765 scopus 로고    scopus 로고
    • PPARa in obesity: Sex diference and estrogen involvement
    • Yoon M. (2010). PPARa in obesity: sex diference and estrogen involvement. PPAR Res, 2010, 584296.
    • (2010) PPAR Res , vol.2010 , pp. 584296
    • Yoon, M.1
  • 32
    • 78449312140 scopus 로고    scopus 로고
    • Evaluation of 8-Week body weight control program including sea tangle (Laminaria japonica) supplementation in korean female college students
    • You JS, Sung MJ, Chang KJ. (2009). Evaluation of 8-week body weight control program including sea tangle (Laminaria japonica) supplementation in Korean female college students. Nutr Res Pract, 3, 307-314.
    • (2009) Nutr Res Pract , vol.3 , pp. 307-314
    • You, J.S.1    Sung, M.J.2    Chang, K.J.3
  • 33
    • 0036195453 scopus 로고    scopus 로고
    • Therapeutic potential of CPT I inhibitors: Cardiac gene transcription as a target
    • DOI 10.1517/13543784.11.3.345
    • Zarain-Herzberg A, Rupp H. (2002). Terapeutic potential of CPT i inhibitors: Cardiac gene transcription as a target. Expert Opin Investig Drugs, 11, 345-356. (Pubitemid 34213389)
    • (2002) Expert Opinion on Investigational Drugs , vol.11 , Issue.3 , pp. 345-356
    • Zarain-Herzberg, A.1    Rupp, H.2
  • 34
    • 77954290399 scopus 로고    scopus 로고
    • Screening for anti-lipase properties of 37 traditional Chinese medicinal herbs
    • Zheng CD, Duan YQ, Gao JM, Ruan ZG. (2010). Screening for anti-lipase properties of 37 traditional Chinese medicinal herbs. J Chin Med Assoc, 73, 319-324.
    • (2010) J Chin Med Assoc , vol.73 , pp. 319-324
    • Zheng, C.D.1    Duan, Y.Q.2    Gao, J.M.3    Ruan, Z.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.