메뉴 건너뛰기




Volumn 32, Issue 2, 2012, Pages 83-91

PTPN2 is associated with Crohn's disease and its expression is regulated by NKX2-3

Author keywords

association; Crohn's disease; gene expression; NKX2 3; PTPN2

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX2.3; UNCLASSIFIED DRUG;

EID: 84863283197     PISSN: 02780240     EISSN: 18758630     Source Type: Journal    
DOI: 10.3233/DMA-2011-0867     Document Type: Article
Times cited : (16)

References (25)
  • 1
    • 44349124113 scopus 로고    scopus 로고
    • The genetics and immunopathogenesis of inflammatory bowel disease
    • DOI 10.1038/nri2340, PII NRI2340
    • J.H. Cho, The genetics and immunopathogenesis of inflammatory bowel disease, Nat Rev Immunol 8 (2008), 458-466. (Pubitemid 351733422)
    • (2008) Nature Reviews Immunology , vol.8 , Issue.6 , pp. 458-466
    • Cho, J.H.1
  • 2
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • WTCCC
    • WTCCC, Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447 (2007), 661-678.
    • (2007) Nature , vol.447 , pp. 661-678
  • 6
    • 0035313868 scopus 로고    scopus 로고
    • Combinatorial control of the specificity of protein tyrosine phosphatases
    • DOI 10.1016/S0955-0674(00)00196-4
    • N.K. Tonks and B.G. Neel, Combinatorial control of the specificity of protein tyrosine phosphatases, Curr Opin Cell Biol 13 (2001), 182-195. (Pubitemid 32209219)
    • (2001) Current Opinion in Cell Biology , vol.13 , Issue.2 , pp. 182-195
    • Tonks, N.K.1    Neel, B.G.2
  • 7
    • 1942489307 scopus 로고    scopus 로고
    • T-cell protein tyrosine phosphatase deletion results in progressive systemic inflammatory disease
    • DOI 10.1182/blood-2003-09-3153
    • K.M. Heinonen, F.P. Nestel, E.W. Newell, G. Charette, T.A. Seemayer, M.L. Tremblay and W.S. Lapp, T-cell protein ty-rosine phosphatase deletion results in progressive systemic inflammatory disease, Blood 103 (2004), 3457-3464. (Pubitemid 38525678)
    • (2004) Blood , vol.103 , Issue.9 , pp. 3457-3464
    • Heinonen, K.M.1    Nestel, F.P.2    Newell, E.W.3    Charette, G.4    Seemayer, T.A.5    Tremblay, M.L.6    Lapp, W.S.7
  • 8
    • 78651070199 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase N2 regulates tnfalpha-induced signalling and cytokine secretion in human intestinal epithelial cells
    • M. Scharl, D.F. McCole, A. Weber, S.R. Vavricka, P. Frei, S. Kellermeier, T. Pesch, M. Fried and G. Rogler, Protein tyrosine phosphatase N2 regulates TNFalpha-induced signalling and cytokine secretion in human intestinal epithelial cells, Gut 60 (2011), 189-197.
    • (2011) Gut , vol.60 , pp. 189-197
    • Scharl, M.1    McCole, D.F.2    Weber, A.3    Vavricka, S.R.4    Frei, P.5    Kellermeier, S.6    Pesch, T.7    Fried, M.8    Rogler, G.9
  • 10
    • 67651085303 scopus 로고    scopus 로고
    • Association of a nkx2-3 polymorphism with crohn's disease and expression of nkx2-3 is up-regulated in B cell lines and intestinal tissues with crohn's disease
    • W. Yu, Z. Lin, A.A. Kelly, J.P. Hegarty, L.S. Poritz, Y. Wang, T. Li, S. Schreiber and W.A. Koltun, Association of a Nkx2-3 polymorphism with Crohn's disease and expression of Nkx2-3 is up-regulated in B cell lines and intestinal tissues with Crohn's disease, Journal of Crohn's and Colitis 3 (2009), 189-195.
    • (2009) Journal of Crohn's and Colitis , vol.3 , pp. 189-195
    • Yu, W.1    Lin, Z.2    Kelly, A.A.3    Hegarty, J.P.4    Poritz, L.S.5    Wang, Y.6    Li, T.7    Schreiber, S.8    Koltun, W.A.9
  • 12
    • 84863789923 scopus 로고    scopus 로고
    • Genes differentially regulated by NKX2-3 in B cells between ulcerative colitis and Crohn's disease patients and possible involvement of EGR1
    • (accepted, in press)
    • W. Yu, Z. Lin, J.P. Hegarty, X. Chen, A.A. Kelly, Y. Wang, L.S. Poritz and W.A. Koltun, Genes differentially regulated by NKX2-3 in B cells between ulcerative colitis and Crohn's disease patients and possible involvement of EGR1, Inflammation (2011), (accepted, in press).
    • (2011) Inflammation
    • Yu, W.1    Lin, Z.2    Hegarty, J.P.3    Chen, X.4    Kelly, A.A.5    Wang, Y.6    Poritz, L.S.7    Koltun, W.A.8
  • 13
    • 79957541726 scopus 로고    scopus 로고
    • Nkx2-3 tran-scriptional regulation of endothelin-1 and VEGF signaling in human intestinal microvascular endothelial cells
    • W. Yu, J.P. Hegarty, A. Berg, X. Chen, G. West, A.A. Kelly, Y. Wang, L.S. Poritz, W.A. Koltun and Z. Lin, NKX2-3 Tran-scriptional Regulation of Endothelin-1 and VEGF Signaling in Human Intestinal Microvascular Endothelial Cells, PLoS One 6 (2011), e20454.
    • (2011) PLoS One , vol.6
    • Yu, W.1    Hegarty, J.P.2    Berg, A.3    Chen, X.4    West, G.5    Kelly, A.A.6    Wang, Y.7    Poritz, L.S.8    Koltun, W.A.9    Lin, Z.10
  • 16
    • 78149359520 scopus 로고    scopus 로고
    • Genes Regulated by Nkx2-3 in Sporadic and Inflammatory Bowel Disease-Associated Colorectal Cancer Cell Lines
    • W. Yu, Z. Lin, D.M. Pastor, J.P. Hegarty, X. Chen, A.A. Kelly, Y. Wang, L.S. Poritz and W.A. Koltun, Genes Regulated by Nkx2-3 in Sporadic and Inflammatory Bowel Disease-Associated Colorectal Cancer Cell Lines, Dig Dis Sci 55 (2010), 3171-3180.
    • (2010) Dig Dis Sci , vol.55 , pp. 3171-3180
    • Yu, W.1    Lin, Z.2    Pastor, D.M.3    Hegarty, J.P.4    Chen, X.5    Kelly, A.A.6    Wang, Y.7    Poritz, L.S.8    Koltun, W.A.9
  • 17
    • 61849135255 scopus 로고    scopus 로고
    • T-cell protein tyrosine phosphatase is a key regulator in immune cell signaling: Lessons from the knockout mouse model and implications in human disease
    • K.M. Doody, A. Bourdeau and M.L. Tremblay, T-cell protein tyrosine phosphatase is a key regulator in immune cell signaling: lessons from the knockout mouse model and implications in human disease, Immunol Rev 228 (2009), 325-341.
    • (2009) Immunol Rev , vol.228 , pp. 325-341
    • Doody, K.M.1    Bourdeau, A.2    Tremblay, M.L.3
  • 19
    • 34250675278 scopus 로고    scopus 로고
    • Current and future anti-TNF therapy for inflammatory bowel disease
    • DOI 10.1007/s11938-007-0013-3
    • M.T. Osterman and G.R. Lichtenstein, Current and Future Anti-TNF Therapy for Inflammatory Bowel Disease, Curr Treat Options Gastroenterol 10 (2007), 195-207. (Pubitemid 46938929)
    • (2007) Current Treatment Options in Gastroenterology , vol.10 , Issue.3 , pp. 195-207
    • Osterman, M.T.1    Lichtenstein, G.R.2
  • 20
    • 31144445210 scopus 로고    scopus 로고
    • Inflammatory bowel disease requires the interplay between innate and adaptive immune signals
    • DOI 10.1038/sj.cr.7310009, PII 7310009
    • D. Shi, J. Das and G. Das, Inflammatory boweldisease requires the interplay between innate and adaptive immune signals, Cell Res 16 (2006), 70-74. (Pubitemid 43129310)
    • (2006) Cell Research , vol.16 , Issue.1 , pp. 70-74
    • Shi, D.1    Das, J.2    Das, G.3
  • 21
    • 0037769202 scopus 로고    scopus 로고
    • + myeloid cells lacking T cell protein tyrosine phosphatase inhibit lymphocyte proliferation by an IFN-γ- and nitric oxide-dependent mechanism
    • M. Dupuis, M. De Jesus Ibarra-Sanchez, M.L. Tremblay and P. Duplay, Gr-1+ myeloid cells lacking T cell protein tyro-sine phosphatase inhibit lymphocyte proliferation by an IFN-gamma-and nitric oxide-dependent mechanism, J Immunol 171 (2003), 726-732. (Pubitemid 36871382)
    • (2003) Journal of Immunology , vol.171 , Issue.2 , pp. 726-732
    • Dupuis, M.1    Ibarra-Sanchez, M.D.J.2    Tremblay, M.L.3    Duplay, P.4
  • 22
    • 34248334251 scopus 로고    scopus 로고
    • TC-PTP-deficient bone marrow stromal cells fail to support normal B lymphopoiesis due to abnormal secretion of interferon-γ
    • DOI 10.1182/blood-2006-08-044370
    • A. Bourdeau, N. Dube, K.M. Heinonen, J.F. Theberge, K.M. Doody and M.L. Tremblay, TC-PTP-deficient bone marrow stromal cells fail to support normal B lymphopoiesis due to abnormal secretion of interferon-{gamma}, Blood 109 (2007), 4220-4228. (Pubitemid 46743386)
    • (2007) Blood , vol.109 , Issue.10 , pp. 4220-4228
    • Bourdeau, A.1    Dube, N.2    Heinonen, K.M.3    Theberge, J.-F.4    Doody, K.M.5    Tremblay, M.L.6
  • 23
    • 0031647381 scopus 로고    scopus 로고
    • Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner
    • Y. Fu, W. Yan, T.J. Mohun and S.M. Evans, Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner, Development 125 (1998), 4439-4449. (Pubitemid 28564288)
    • (1998) Development , vol.125 , Issue.22 , pp. 4439-4449
    • Fu, Y.1    Yan, W.2    Mohun, T.J.3    Evans, S.M.4
  • 24
    • 0030899175 scopus 로고    scopus 로고
    • The mouse Nkx2-3 homeodomain gene is expressed in gut mesenchyme during pre- and postnatal mouse development
    • O. Pabst, A. Schneider, T. Brand and H.H. Arnold, The mouse Nkx2-3 homeodomain gene is expressed in gut mesenchyme during pre-and postnatal mouse development, Dev Dyn 209 (1997), 29-35. (Pubitemid 27188336)
    • (1997) Developmental Dynamics , vol.209 , Issue.1 , pp. 29-35
    • Pabst, O.1    Schneider, A.2    Brand, T.3    Arnold, H.-H.4
  • 25
    • 0037446534 scopus 로고    scopus 로고
    • Architectural defects in the spleens of Nkx2-3-deficient mice are intrinsic and associated with defects in both B cell maturation and T cell-dependent immune responses
    • D. Tarlinton, A. Light, D. Metcalf, R.P. Harvey and L. Robb, Architectural defects in the spleens of Nkx2-3-deficient mice are intrinsic and associated with defects in both B cell maturation and T cell-dependent immune responses, J Immunol 170 (2003), 4002-4010. (Pubitemid 36428161)
    • (2003) Journal of Immunology , vol.170 , Issue.8 , pp. 4002-4010
    • Tarlinton, D.1    Light, A.2    Metcalf, D.3    Harvey, R.P.4    Robb, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.