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Volumn 3, Issue 3, 2012, Pages 379-384

Structure-based optimization of the piperazino-containing 1,3 -disubstituted ureas affording sub-nanomolar inhibitors of soluble epoxide hydrolase

(6) Huang, Shao Xu a Cao, Bin a Morisseau, Christophe b Jin, Yi c Hammock, Bruce D b Long, Ya Qiu a

a SHANGHAI INSTITUTE OF MATERIA MEDICA (China)

b UNIVERSITY OF CALIFORNIA (United States)

c YUNNAN UNIVERSITY (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADAMANTANE DERIVATIVE; BENZENE DERIVATIVE; CARBONYL DERIVATIVE; EPOXIDE HYDROLASE; EPOXIDE HYDROLASE INHIBITOR; HYDROLASE INHIBITOR; PIPERAZINE DERIVATIVE; UNCLASSIFIED DRUG; UREA DERIVATIVE; WATER;

ARTICLE; DRUG SOLUBILITY; DRUG STRUCTURE; ENZYME INHIBITION; HYDROPHILICITY; LIPOPHILICITY; PHARMACOPHORE; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

EID: 84863268463 PISSN: 20402503 EISSN: 20402511 Source Type: Journal
DOI: 10.1039/c2md00288d Document Type: Article

Times cited : (14)

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